Wed.Oct 18, 2023

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Zuckerberg and Chan announce a New York biohub to build disease-fighting cellular machines

STAT

Meta founder Mark Zuckerberg and his wife, pediatrician and philanthropist Priscilla Chan, announced on Wednesday plans to invest $250 million over 10 years to establish a new “biohub” in New York City focused on building a new class of cellular machines that can surveil the body and snuff out disease. The new initiative, publicly revealed at the 2023 STAT Summit and previewed exclusively to STAT, is the latest program from the Chan Zuckerberg Initiative, or CZI, a company the coup

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NICE recommends Roche’s Columvi for advanced lymphoma in UK

Pharma Times

Around 700 people in the UK could benefit from the new treatment - News - PharmaTimes

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Trending Sources

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STAT+: In an unusual arrangement, UnitedHealth’s board chair also owns a personal investment firm

STAT

Stephen Hemsley, the former CEO of UnitedHealth Group and its current board chair, also owns an investment firm that manages his own portfolio of UnitedHealth stock and oversees other wealthy individuals’ accounts that have held shares of companies that have direct business with or indirect ties to United. It’s an unusual arrangement for someone in such a prominent role at one of the largest health care corporations in the world, according to several experts in securities and corpo

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UKRI awards £10m in funding to tackle antimicrobial resistance

Pharma Times

UK researchers can apply to receive a share of £3m to set up transdisciplinary networks - News - PharmaTimes

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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STAT+: The Ozempic panic: Why a market frenzy over new weight loss drugs defies logic

STAT

There’s a specter haunting Wall Street. It started in biotech, where companies making drugs for the obesity-related liver disease NASH saw their valuations crash on the assumption that GLP-1 weight loss treatments would cut them out of the market. Then the Ozempic panic came for dialysis firms, whose stocks fell about 20% in a single day on the news that Novo Nordisk’s medicine had delayed the progression of kidney disease in a study enrolling people with type 2 diabetes.

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For women’s health, Organon changed the financial language

PharmaVoice

Organon is partnering with governments, banks, NGOs and investors on programs to improve women’s health through results-based financing.

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Hyloris wins painkiller approval amidst amplified anti-opioid efforts

Pharmaceutical Technology

The FDA approved Hyloris’s non-opioid painkiller as the agency increases efforts to mitigate an opioid crisis.

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STAT+: Senate Finance targets Medicare Advantage brokers

STAT

Senate Finance Committee members from both parties took aim Wednesday at insurance brokers that sell plans for large Medicare Advantage insurers. Older adults at times have more than 100 plan options, and brokers help them choose the right one. But brokers can be incentivized by large insurance companies to aggressively sell plans that are a poor fit for the Medicare beneficiaries they’re supposed to help.

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Medical drone delivery set for global take off

pharmaphorum

Medical drone delivery set for global take off Mike.

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Lotte Knudsen, who pushed Novo Nordisk into the Ozempic era, wins STAT Innovation award

STAT

Back in the 1990s, scientist Lotte Bjerre Knudsen was tasked with revitalizing a floundering program at Novo Nordisk that had been trying to harness the newly-discovered GLP-1 hormone into viable diabetes drug candidates. At the time, many of Knudsen’s bosses had already lost hope for the program. Novo’s focus, after all, was on insulin, and the naturally occurring GLP-1 hormone had too short a half-life to use as a drug.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Seagen wins future royalties in Enhertu patent dispute

pharmaphorum

Seagen wins future royalties in Enhertu patent dispute Phil.

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STAT+: Why doesn’t everyone lose weight on Ozempic-type drugs? Researchers look for genetic clues

STAT

DALLAS — Treatments like Ozempic, Wegovy, and Mounjaro have been hailed for showing 15% to over 20% weight loss in trials, but those are just averages. In reality, there are big variations in how much weight people lose on the therapies, and it’s unclear what explains those differences. One way researchers are trying to figure this out is by focusing on genes.

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First-in-class phosphate absorption inhibitor approved by FDA

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved XPHOZAH ® (tenapanor), the first and only phosphate absorption inhibitor. Ardelyx’s first-in-class oral treatment is indicated to reduce serum phosphorus in adults with chronic kidney disease ( CKD ) on dialysis as add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant to phosphate binder therapy.

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STAT+: Biotech power broker John Maraganore offers advice to the next crop of entrepreneurs

STAT

During a nearly two-decade stint as Alnylam’s founding CEO, John Maraganore took a promising but unproven approach for treating genetic disease and built a new class of medicines and what is now a nearly $21 billion company. His next goal? Helping the next generation of budding biotech entrepreneurs. Since stepping down as Alnylam CEO in 2021, Maraganore has spent much of his time passing down his knowledge to up-and-coming biotech CEOs.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Evident Vascular raises $35m, and other digital financings

pharmaphorum

Evident Vascular raises $35m, and other digital financings Phil.

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Opinion: Listen: Why long Covid might predate the pandemic

STAT

Since the early days of the pandemic, long Covid has haunted us: Even a mild acute infection might leave you with life-altering consequences. And for many, that has, sadly, turned out to be the case. While research suggests long Covid rates are falling, it still affects millions. In June 2023, 6% of Americans reported experiencing long Covid. But what if long Covid isn’t the right way to think about what they are going through?

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Balancing the health ecosystem: Putting the patient first

pharmaphorum

Balancing the health ecosystem: Putting the patient first Mike.

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How rising stars in science and medicine think about mentorship and bouncing back from rejection

STAT

At the age of 26, Lauren Ghazal was diagnosed with Hodgkin’s lymphoma just months into her Ph.D. program in nursing theory at New York University. She experienced firsthand how the financial burden of undergoing cancer treatment, along with the emotional and physical toll of the disease itself, can lead to overwhelming distress in patients. Now, as an assistant professor at the University of Rochester in the School of Nursing, she researches health and quality of life outcomes among young

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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More than 31,000 ARRS staff recruited since 2019

The Pharmacist

More than 31,000 staff – including pharmacists, mental health practitioners and social prescribers – have been recruited to work in general practice under the Additional Roles Reimbursement Scheme (ARRS) since 2019. The total was announced today by NHS England (NHSE), alongside a video to raise awareness of the roles available to patients, after a new […] The post More than 31,000 ARRS staff recruited since 2019 appeared first on The Pharmacist.

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STAT+: In drug development, large pharma companies’ staying power provides them an edge, Lilly’s chief medical officer says

STAT

Among drugmakers, big pharma has a reputation of being stodgy and old-fashioned, while biotech startups are seen as rife with fresher thinking — companies where innovative solutions are actually hatched and are then acquired by those older, bigger firms. But at the STAT Summit on Wednesday, Daniel Skovronsky, the chief scientific and medical officer at Eli Lilly, discussed how Lilly has been able to crack both obesity and Alzheimer’s , two areas that have long stumped drug develope

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Elements in precision oncology

pharmaphorum

Elements in precision oncology Mike.

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Wegovy doesn’t work for everyone, and no one’s quite sure why

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with a critical look at the mounting Ozempic panic, the case against a former meme stock, and a biotech pivot with a warm reception.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Lisata receives orphan drug designation for pancreatic cancer therapy

Pharmaceutical Technology

Lisata has received orphan drug designation from the EMA's Committee for Orphan Medicinal Products for LSTA1 to treat pancreatic cancer.

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Opinion: STAT+: Preventive drugs may be the best solution to the antibiotic resistance crisis

STAT

The antibiotics crisis is a silent pandemic that threatens to knock modern society back into the medieval age of therapeutic leaches and serum therapy. A world where an accidental scratch in the rose garden can kill. Why is the supply of new antibiotics so thin, and growing thinner? A high-profile Wall Street Journal article recently highlighted what everyone knows: There is huge need but no market demand.

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Sanofi treatment could slow type 1 diabetes progression

European Pharmaceutical Review

TZIELD (teplizumab-mzwv) has demonstrated TZIELD’s potential to slow disease progression in newly diagnosed children and adolescents with Stage 3 type 1 diabetes. Data from the Phase III PROTECT clinical trial , presented at the 2023 Annual ISPAD Conference, showed that superior beta cell preservation was observed compared to placebo. As the primary endpoint, 94.9 percent of participants in the TZIELD group maintained peak C-peptide levels ≥0.2 pmol/mL.

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STAT+: Pharmalittle: Biotech investors push to extend time before Medicare price negotiations; RiteAid closings could cause pharmacy deserts

STAT

Good morning, everyone, and how are you today? We are doing just fine, thank you. After all, the birds are still chirping and a cool breeze is wafting by the surprisingly sedate Pharmalot campus. Moreover, this marks the middle of the week, which means we have managed to survive this far. And this calls for celebration, yes? So please join us as we hoist another cup of delicious stimulation.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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BrainStorm, after setbacks, withdraws approval application for ALS drug

BioPharma Dive

A panel of FDA advisers last month found BrainStorm’s data unconvincing. The company now says a Phase 3b study will be needed for its NurOwn cell therapy to have a shot at an approval.

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STAT+: Biotech investors push to extend time before pills are subject to price negotiations

STAT

The fight over drug prices is far from over. Investors in biopharma companies, who lobbied vigorously — but unsuccessfully — against allowing Medicare to negotiate drug prices, are trying a new tactic to preserve their profits. A group called the Incubate Coalition, comprising the venture capital firms that bankroll most biotech startups, is pressing US lawmakers to extend by four years the time that pills can be on the market before they become subject to price negotiations w

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Exclusive: Lack of pharmacy representation on ICBs, warns health committee chair

The Pharmacist

Integrated care boards (ICBs) do not have ‘enough’ pharmacy representation, the Health and Social Care Committee chair Steve Brine has told The Pharmacist. The former pharmacy minister and Conservative MP for Winchester also said he felt primary care networks (PCNs) were ‘way too GP dominated’. Mr Brine was speaking to The Pharmacist following an address […] The post Exclusive: Lack of pharmacy representation on ICBs, warns health committee chair appeared first on The Pharmacist.

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Ardelyx wins FDA approval for phosphate absorption inhibitor

Pharmaceutical Technology

The company also secured $50m in debt financing to support the commercial launch of Xphozah in November 2023.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.