Sat.Apr 29, 2023 - Fri.May 05, 2023

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What explains rare heart condition among young men after Covid vaccines? A new study offers clues

STAT

A new study sheds light on what may be causing very rare cases of heart inflammation in young men after receiving an mRNA Covid vaccine. Early hypotheses as to what was driving the heart inflammation, called myocarditis , included an allergic response to the vaccine, vaccine-induced antibodies, or an autoimmune response in which the immune system attacks the body’s own healthy tissue by mistake.

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A CEO’s quest to solve a 400-year-old medical mystery — and he’s also a patient

PharmaVoice

The CEO of Ventoux Biosciences has the disease that his company is aiming to treat, and it's driving him to find better medications.

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FDA approves first RSV vaccine, clearing GSK’s Arexvy for older adults

BioPharma Dive

The decision represents the first fruits of a scientific breakthrough a decade ago that gave drugmakers, among them GSK, Pfizer and Moderna, a blueprint for an effective shot against the virus.

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Advice For New Pharmacists: Lessons Form The Front Lines

ID Stewardship

In this article advice for new pharmacists is provided by a pharmacist with 15 years of experience and answers are sourced from commentary on Twitter as well. Composed By: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 1 May 2023 Recently while attending the American Pharmacist Association’s annual meeting in Phoenix, AZ I walked by a grown man at a breakfast bar wearing a head-to-toe onesie patterned with Dunkin’ Doughnuts (DD) logos.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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For Eli Lilly’s head scientist, Alzheimer’s results cap a 25-year scientific quest

STAT

If you flip to the 1,031st page of the May 1998 edition of the Journal of Cell Biology, you’ll find the first scientific byline for Daniel Skovronsky, then a young trainee at the University of Pennsylvania, on an article describing how beta-amyloid, a vexing molecule thought to play a role in Alzheimer’s disease, was more complicated than the field understood.

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Taking your biotech global? Here’s how you can navigate cultural norms

PharmaVoice

What’s so different about doing pharma business in the U.K. versus Japan? One of Moderna’s top brass shares her tips for navigating choppy cultural waters.

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More Trending

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New PhRMA Ad Campaign Sheds Light on PBM Abuses

PhRMA

The Pharmaceutical Research and Manufacturers of America (PhRMA) today launched a new ad campaign that continues to shed light on the role of pharmacy benefit managers (PBMs) in driving up health care costs and denying coverage of lifesaving medicines.

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Opinion: Do masks work? Randomized controlled trials are the worst way to answer the question

STAT

Early in the Covid-19 pandemic, before we had vaccines and effective medical procedures, the only ways to prevent transmission of the virus were behavioral measures like face masks and social distancing. There was (and continues to be) a desperate hunger for definitive studies telling us how well specific measures would work, with specific publics, in specific settings, for specific strains of the novel and changing virus.

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From science to strategy, this exec is painting Genmab’s bigger picture into the next decade

PharmaVoice

Martine van Vugt, recently named Genmab’s chief strategy officer and executive vice president, aims to usher in the company’s next wave of "knock your socks off" antibodies.

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Sanofi strikes a $150M deal for Maze’s Pompe disease drug

BioPharma Dive

The cash influx extends Maze’s financial runway into 2025, giving the South San Francisco company time to advance other drug candidates into testing.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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'Utterly devastating’: Cost-of-living crisis hits OTC medicines access

The Pharmacist

In Shilpa Shah’s area of North-East London, people ‘can't afford to be ill’. With many people accessing free prescriptions, community pharmacists in the area tend to give advice and recommend home remedies for self-limiting minor ailments, instead of over-the-counter treatments that patients would have to pay for. For a sore throat, patients might be told […] The post 'Utterly devastating’: Cost-of-living crisis hits OTC medicines access appeared first on The Pharmacist.

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CDC to cut back on Covid data it collects as public health emergency ends

STAT

The ending of the public health emergency for Covid-19 will force the Centers for Disease Control and Prevention to cut back on the data it collects to analyze how much illness the SARS-CoV-2 virus is causing in the future, the CDC announced Friday. But some of the data metrics the CDC will no longer be able to collect are of lesser value now than they were at earlier points in the pandemic, agency officials explained in a press briefing Thursday in advance of Friday’s release of two arti

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Emalex aims at a first-in-class breakthrough for Tourette syndrome

PharmaVoice

With its phase 3 candidate, the biotech believes it can move the field beyond antipsychotics to a more effective approach.

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Lilly drug slows Alzheimer’s decline in large study

BioPharma Dive

The company plans to quickly submit an application for U.S. approval based on the trial results, which showed a consistent benefit to treatment with the drug, called donanemab.

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Americans want state policymakers to lower out-of-pocket costs

PhRMA

Too many Americans are struggling to access and afford their health care. While policy debates about how to address these issues can seem never ending, American adults largely agree on what state policymakers should be doing to help deliver relief to patients at the pharmacy counter.

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Opinion: Long waits to see a doctor are a public health crisis

STAT

In 2004, the physician search firm Merritt Hawkins first issued their Survey of Physician Appointment Wait Times. That year, the national average wait to get in to see a new physician was 21 days, an unacceptable amount of time to wait to access care. But that number has only gotten worse. In their 2022 survey , the wait for a new patient appointment increased to an average of 26 days.

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Attracting up-and-coming talent in biotech

PharmaVoice

The CEO of a Bay-area startup shares his strategies for growing a team from the ground up.

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Pfizer turns focus to new drugs as COVID vaccine revenue falls

BioPharma Dive

The drugmaker beat Wall Street’s first quarter forecasts despite a sales drop that puts pressure on it to succeed with upcoming market launches.

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Astellas Pharma agrees to buy Iveric bio for about $5.9bn

Pharmaceutical Technology

Astellas Pharma has entered into a definitive agreement to buy US-based biopharmaceutical company Iveric bio, in a deal valued at nearly $5.9bn. Under the deal terms, the company, through Astellas US Holding’s wholly owned subsidiary Berry Merger Sub, will acquire all the outstanding Iveric Bio shares for $40.00 in cash for each share. Both the companies’ Boards of Directors have unanimously approved the deal.

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STAT+: What to know about the upcoming readout of Eli Lilly’s experimental Alzheimer’s therapy

STAT

Eli Lilly is nearing the readout from a pivotal study of its experimental treatment for Alzheimer’s disease. The approval of a similar medicine earlier this year has wrung risk from the outcome, but for the same reason, expectations for strong results are higher. The Lilly drug, called donanemab, is an antibody that targets accumulated plaques in the brain called amyloid.

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A biopharma CEO opens up about executive salaries — and why he wants to change the status quo

PharmaVoice

With leaders at the biggest biopharma companies bringing in millions, the CEO of Corvus Pharmaceuticals opted for a pay cut to pour more funds into science.

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Valneva, Pfizer push back timeline for Lyme disease vaccine

BioPharma Dive

After issues with a contract research group, the partners now expect to file an approval application for their shot in 2026, one year later than initially anticipated.

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Pharma á la carte – 05/04/2023

The Honest Apothecary

Here I share some of the latest news, articles, editorials, or blog posts that fall generally under the theme of Pharma or healthcare. I might throw in a something off-topic from time to time which I found while wandering throughout the endless hallways and corridors of the internet. All article shared will be free to read and not locked behind an annoying paywall.

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STAT+: Sam Waksal and Jeremy Levin plot ‘the turnaround story of the century’

STAT

Over glasses of Chablis at Fleming by Le Bilboquet in Manhattan, two longtime friends and biotech lifers hashed out the deal that will bring their wending and colorful careers back together after three decades. Jeremy Levin, the professorial executive who has become one of the industry’s loudest voices on matters of social justice, is getting back into business with Sam Waksal, a hit-making drug developer with a gift for eloquence and a biography that doubles as biotech’s great unp

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Episode 813: Can you give lactated ringer’s solution to a patient with elevated lactate?

Pharmacy Joe

In this episode, I’ll discuss giving lactated ringer’s solution to a patient with elevated lactate. Episode 813: Can you give lactated ringer’s solution to a patient with elevated lactate? Subscribe on iTunes , Android , or Stitcher Lactated ringers is considered a suitable fluid for resuscitation in sepsis. In fact, it is becoming more common to use it as a resuscitation fluid as it contains a more physiologic level of chloride than normal saline and is not expected to cause hyperchlorem

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Ovid partners with Waksal startup to develop drugs for rare brain disorders

BioPharma Dive

Founded by Sam Waksal, Graviton Biosciences is developing drugs that block an enzyme called ROCK2, which drew the interest of neurology-focused Ovid.

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Why Mankind Pharma’s IPO could be a milestone

Express Pharma

Mankind Pharma’s successful IPO raises hope for IPO-wannabes but the real hard work starts after the IPO party ends. Most companies face an IPO hangover, with share prices dipping post the IPO as they struggle to meet raised investor expectations. Will Mankind Pharma buck this trend? Mankind Pharma’s IPO was oversubscribed 15.32 times, thanks largely to qualified institutional buyers (QIBs).

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Study: Ingredient found in salad bowls and burger wrappers less safe than previously thought

STAT

A compostable salad bowl seems like an Earth-friendly way to enjoy a healthy lunch. But the toxic chemicals used in containers like molded-fiber salad bowls, sandwich wrappers, and French fry pouches may be leaching into food despite efforts to make those materials safer, according to the results of a study published in March in the journal Environmental Science and Technology.

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Forge Biologics and Labcorp partner for gene therapies development

Pharmaceutical Technology

Forge Biologics and global life sciences company Labcorp have announced a strategic adeno-associated virus (AAV) gene therapy development and manufacturing collaboration. Gene therapy clients will gain access to coordinated scientific expertise, drug development services and AAV manufacturing capabilities, advancing the development of new gene therapies.

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Initial launches with $75M and a new idea for targeting problematic proteins

BioPharma Dive

The company was co-founded by, among others, Jamie Cate, husband of CRISPR pioneer Jennifer Doudna, and Kevan Shokat, a chemical biologist whose previous work helped lead to KRAS-targeting cancer drugs.

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How is Your Follow-Through as a Leader?

The Honest Apothecary

Do you find yourself frequently needing to remind your boss about something they were supposed to do? Or are you, perhaps, frequently guilty of dropping the ball on a piece of a project that you needed to get done? Maybe your particular struggle is in responding to requests for information or feedback. Or do people need to reach out to you 2, 3, 4 times or more to try and get your input or advice?

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Report on medical access finds one-third of Black Americans live in ‘cardiology deserts’

STAT

Many Black Americans would have to travel across county lines just to find an open spot with a cardiologist, a new analysis found. About 16.8 million Black Americans — roughly 1 in 3 — live in counties with little or no access to heart specialists, according to a report from GoodRx, a telehealth company that provides drug discounts and also researches health trends.

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How will green chemistry transform the future of pharma manufacturing

Express Pharma

The idea of green chemistry was initially developed as a response to the Pollution Prevention Act of 1990, which declared that US national policy should eliminate pollution by improved design including cost-effective changes in products, processes, use of raw materials, and recycling instead of treatment and disposal. The 12 Principles of Green Chemistry were published in 1998, providing the new field with a clear set of guidelines for further development.

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Apellis reports strong start for new vision loss drug

BioPharma Dive

Higher-than-expected sales of the geographic atrophy therapy Syfovre pushed shares in Apellis higher, and could add to speculation about a takeover.

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Vertex secures FDA clearance for infants’ cystic fibrosis therapy

Pharmaceutical Technology

Vertex Pharmaceuticals has received approval from the US Food and Drug Administration (FDA) for KALYDECO (ivacaftor) to treat children with cystic fibrosis (CF) aged between one and four months. The approval allows KALYDECO to be used in infants who have at least one mutation in their cystic fibrosis transmembrane conductance regulator (CFTR) gene that is responsive to the therapy, on the basis of clinical and/or in vitro assay results.