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Hiya. Today, we explore how traditionally underserved sickle cell patients became early recipients of a futuristic gene-editing therapy, see another generative AI drug discovery deal forged, and more.

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The need-to-know this morning

• Roche is paying $2.7 billion for Carmot Therapeutics, a privately held company developing treatments for obesity.
• Eyepoint Pharmaceuticals saw its share price nearly quadruple in pre-market trading after its treatment for macular degeneration met its goals in a Phase 2 study.
• The FDA approved Eli Lilly’s Jaypirca as a treatment for chronic lymphocytic leukemia, widening its availability beyond mantle cell lymphoma.

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