Trending Articles

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STAT+: Gene therapies for deafness dredge up an old question: Do deaf people want a ‘cure’?

STAT

When Yilai Shu was training to be an otolaryngologist in Shanghai, in the mid 2000s, he often met parents with congenitally deaf kids. “They always asked me, ‘Do you have any drugs to treat our kids?’ said Shu, who is hearing and a professor at Fudan University in China. “That’s what really inspired me to think about developing a drug.

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As weight loss booms, drugmakers look for an edge with oral options

PharmaVoice

Supply of GLP-1 medications falls well short of demand, and oral versions of the drugs loom over Eli Lilly and Novo Nordisk’s dominance.

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AZ’s Dato-DXd misses survival endpoint in lung cancer trial

pharmaphorum

The overall survival (OS) data has come in from the TROPION-Lung01 study of AstraZeneca and Daiichi Sankyo’s datopotamab deruxtecan (Dato-DXd) in lung cancer – and the result likely isn’t what they were hoping for.

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Researchers combine herpes virus with cancer vaccine to treat brain cancer in children

Pharma Times

High-grade gliomas are rare, malignant tumours which account for up to 12% of all childhood brain tumours

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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With Duchenne decision ahead, FDA’s Marks pushes for speedy gene therapy approvals

BioPharma Dive

But the head of the FDA’s CBER office didn’t tip where the agency stands on potentially broadening use of Sarepta’s Duchenne gene therapy Elevidys.

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Opinion: The world needs the new pandemic treaty

STAT

At the height of the Covid-19 pandemic, 25 heads of government issued an extraordinary call for a new international treaty for preventing, preparing for, and responding to pandemics. For two years, World Health Organization member states have been negotiating an international agreement scheduled for adoption at the World Health Assembly this month. Yet, late Friday in Geneva, negotiations ground to a halt.

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Tony Blair Institute weighs in on use of NHS patient data

pharmaphorum

A think tank set up by former UK Prime Minister Tony Blair has called for the formation of a public-private trust that could oversee the sharing of anonymised patient data with trusted researchers.

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Biogen Agrees to Acquire HI-BIO for $1.15 Billion

Pharmaceutical Commerce

The deal features felzartamab, an investigational anti-CD38 monoclonal antibody, whose clinical outcomes have shown potential to tackle various immune-mediated diseases.

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ASCO24: An early look at cancer drug study results

BioPharma Dive

Clinical trial abstracts posted by ASCO Thursday give a peek at anticipated datasets from Immunocore, Merck & Co., J&J and Arcus Biosciences.

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New evidence supports fear that drinking raw milk containing bird flu viruses may be dangerous

STAT

A new study published Friday provides more evidence of the potential danger of drinking unpasteurized, or raw, milk containing H5N1 avian flu viruses. The work , published in the New England Journal of Medicine, showed that mice that were fed milk from H5N1-infected cows became very ill.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Asahi Kasei Medical completes new assembly plant for Planova virus removal filters

Express Pharma

Asahi Kasei Medical has completed the construction of its third assembly plant for Planova virus removal filters in Nobeoka, Miyazaki, Japan, and held its completion ceremony on May 24, 2024. The bioprocess business of Asahi Kasei Medical comprises Planova virus removal filters and equipment used in the manufacturing process of biotherapeutic products such as biopharmaceuticals and plasma derivatives, biosafety testing services, and biopharmaceutical Contract Development and Manufacturing (CDMO)

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ASCO: AffyImmune claims a first with CAR-T for solid tumours

pharmaphorum

AffyImmune Therapeutics has recorded what it says is the first documented complete response in a patient with a solid tumour treated with CAR-T therapy. The case comes from a phase 1 study of its ICAM-1 targeting CAR-T autologous candidate AIC100 in patients with relapsed/refractory poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC), which will be reported at the ASCO congress next week.

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King’s Doctoral Training Centre to investigate MS symptom management

Pharma Times

The lifelong autoimmune disease affects more than 150,000 people living in the UK

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Orna, a circular RNA specialist, acquires a buzzy startup

BioPharma Dive

After laying off staff late last year, Orna is expanding through the purchase of ReNAgade Therapeutics, which was built around technology designed to more effectively deliver RNA-based medicines.

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New data show the HPV vaccine prevents cancer in men, too. Why don’t more people get it?

STAT

You’d think if there were a vaccine that would prevent tens of thousands of cases of cancer a year, people would want it for themselves and for their kids. But new data being released Thursday ahead of the annual meeting of the American Society of Clinical Oncology show that just isn’t the case.

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Pharma companies urged to act on antimicrobials to combat drug resistance

Express Pharma

A new report from the Access to Medicine Foundation calls for urgent changes in research and development (R&D) to ensure new antibiotics and antifungals reach patients facing drug-resistant infections. The report examines five late-stage antimicrobial projects targeting severe drug-resistant pathogens, revealing that structured advance planning for access and stewardship is not yet standard among companies.

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GSK’s twice-yearly asthma drug clears two phase 3 trials

pharmaphorum

GSK’s follow-up to its severe asthma therapy Nucala has shown its value in a pair of phase 3 trials, reducing exacerbations compared to placebo with dosing once every six months. The company says new IL-5 inhibitor depemokimab (formerly GSK3511294) has the potential to become the first ultra-long-acting biologic for severe asthma with a six-monthly dosing schedule.

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Small Changes, Big Results: Incorporating Retrieval for Retention into Your Teaching

Pulses

By: Morgan Crawford, PharmD/MS Candidate 2024 and David E. Matthews, PharmD, BCACP On New Year’s Eve, did you make a “New Year’s resolution?” If so, have you managed to keep it? While most resolutions fail , successful ones often involve small, sustainable improvements. Consider this common resolution: to exercise regularly and build strength. A successful individual would not visit the gym for 8 hours daily for the first week of January and then claim to have accomplished their resolution for

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Certain menopausal hormone therapy could raise ovarian cancer risk, study finds

BioPharma Dive

The findings, from two trials involving tens of thousands of women, could influence guidelines around the use of hormonal treatment for menopausal symptoms.

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STAT+: Ozempic cut risk of death in diabetes patients with chronic kidney disease

STAT

Novo Nordisk’s Ozempic cut the risk of death in a trial of patients with type 2 diabetes and chronic kidney disease, suggesting it may offer some added benefits over other classes of drugs approved to treat this population. Specifically, the diabetes drug cut the risk of cardiovascular-related deaths by 29% and all-cause deaths by 20%. Given the study parameters, this implies that over three years, 39 people would need to be treated to prevent one death from any cause, according to new re

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Gerresheimer to acquire Blitz LuxCo Sarl, for EUR 800 million

Express Pharma

Gerresheimer Glas GmbH, an indirect subsidiary of Gerresheimer AG, has signed a purchase agreement with funds advised by Triton for the acquisition of Blitz LuxCo Sarl, the holding company of the Bormioli Pharma Group (Bormioli Pharma). The purchase price is based on a determined enterprise value of around EUR 800 million, which corresponds to an adj.

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Nippon Shinyaku’s DMD drug fails confirmatory trial

pharmaphorum

The future of Nippon Shinyaku’s Duchenne muscular dystrophy (DMD) therapy Viltepso has been thrown into doubt after it failed a confirmatory clinical trial

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New patent for Ferring Pharms drug NOCDURNA

Drug Patent Watch

Annual Drug Patent Expirations for NOCDURNA Nocdurna is a drug marketed by Ferring Pharms Inc and is included in one NDA. It is available from one supplier.

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Swixx BioPharma expands to Latin America through strategic acquisition of Biopas

Outsourcing Pharma

Swixx BioPharma AG, a platform dedicated to unlocking access to e medicines, has announced its strategic expansion into Latin America.

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Michigan reports a human case of bird flu, the nation’s second linked to H5N1 outbreak in dairy cows

STAT

A second human case of bird flu infection linked to the current H5N1 outbreak in dairy cows has been detected, in a farm worker who had exposure to infected cows, Michigan state health authorities announced on Wednesday. In a statement , health officials said the individual had mild symptoms and has recovered. Evidence to date suggests this is a sporadic infection, with no signs of ongoing spread, the statement said.

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PharmaLytica Expo to be held on May 30, 2024

Express Pharma

PharmaLytica Expo, the flagship event within South India’s pharmaceutical industry, is scheduled from May 30 to June, 2024, at HITEX, Hyderabad. Organised by Informa Markets in India, this event marksits 10th edition, providing a business platform for showcasing the latest industry trends, innovations, and business opportunities across Pharma Machinery & Packaging, Lab Analytical & Cleanroom, and Pharma Ingredients segments.

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US senators accuse pharma firms of abusing patent system

pharmaphorum

Lawmakers across the political divide have accused the pharma industry of abusing the patent system to keep the prices of their products as high as possible.

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Sanofi, Formation Bio and OpenAI announce first-in-class AI collaboration

World Pharma News

Sanofi, Formation Bio and OpenAI are collaborating to build AI-powered software to accelerate drug development and bring new medicines to patients more efficiently. The three teams will bring together data, software and tuned models to develop custom, purpose-built solutions across the drug development lifecycle. This represents a first collaboration of its kind within the pharma and life sciences industries.

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Pharmacies given powers to substitute whooping cough antibiotic amid supply disruption

The Pharmacist

The government has reactivated pharmacy powers to swap doses of clarithromycin due to ‘significant ongoing disruption’ to supplies. Pharmacies had been warning they were having to turn patients away and ask for new prescriptions from GPs amid increased demand for the antibiotic due to rising rates of whooping cough. Dr Leyla Hannbeck, the chief executive […] The post Pharmacies given powers to substitute whooping cough antibiotic amid supply disruption appeared first on The Pharmacist.

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Wastewater testing specifically for bird flu virus will scale up nationally in coming weeks

STAT

Less than a month ago, researchers reported for the first time the ability to scan wastewater for signs of the H5 influenza virus currently sickening dairy cows in at least nine states across the U.S. That technology is now at the threshold of real-world use. WastewaterSCAN, an infectious disease-tracking sewage surveillance network led by Stanford University and Emory University in partnership with Verily Life Sciences, has begun scaling up H5-specific testing of samples from all of its 190 sit

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Taro shareholders approve merger with Sun Pharma

Express Pharma

Sun Pharmaceutical Industries and Taro Pharmaceutical Industries, announced that the merger agreement between Taro and Sun Pharma was approved by the affirmative vote of Taro shareholders (including a vote of the majority of shares held by Taro shareholders unaffiliated with Sun Pharma) at an Extraordinary General Meeting and an Ordinary Class Meeting on May 22, 2024.

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Click buys Better assets to speed its digital obesity drive

pharmaphorum

Digital health firm Click Therapeutics has bought the assets of Better Therapeutics to speed up development of a prescription digital therapeutic for obesity

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Bristol Myers Squibb Plans 10-Year Strategy to Expand Access to Medications

PharmaTech

The company is collaborating with the Access to Oncology Medicines Coalition to expand patient access to immuno-oncology therapy Opdivo.

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New GPhC guide on gender services for children and young people

The Pharmacist

A new resource to support pharmacists and pharmacy technicians when providing services to children and young people with gender incongruence or dysphoria has been published by the regulator. The General Pharmaceutical Council (GPhC) has set out a range of questions pharmacy professionals should consider when making decisions about the supply of medicines in this context […] The post New GPhC guide on gender services for children and young people appeared first on The Pharmacist.

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When should we start making H5N1 vaccine, and who will make that decision? In short, it’s complicated

STAT

If the H5N1 bird flu virus ever acquires the ability to transmit easily to and among people — keep your fingers crossed that it doesn’t — the world is going to need serious amounts of vaccine. Like, lakes of the stuff. Some manufacturers have been working with H5N1 viruses for years, producing small batches of doses that have undergone preliminary human testing.

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