Rapid method development to overcome challenges of bi-specific antibody purification
European Pharmaceutical Review
JUNE 27, 2022
For development purposes, bsAbs can be divided into two distinct categories depending on the presence or absence of the crystallizable fragment (Fc) region. Tustian AD, Endicott C, Adams B, et al. Consistent with mAbs, bsAbs that possess an Fc region enable the use of well?established High-throughput column chromatography screening.
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