Anna Yeo/STAT

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason on Signal at JasonMast.05.

Novartis said Thursday it purchased gene therapy startup Kate Therapeutics for up to $1.1 billion in upfront payments and milestones. 

It’s a rare buyout for a field that has quieted over the last couple years, amid a wider biotech downturn and questions about both the effectiveness and profitability of these one-time treatments. 

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With the deal, Novartis will acquire a pipeline of preclinical gene therapies for three different genetic neuromuscular diseases, along with the underlying technology used to create them. Most notably, it joins a high-stakes, fast-moving race to develop a better gene therapy for Duchenne muscular dystrophy than a Sarepta treatment that has divided both regulators and scientists. 

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