Drug Patent Watch

DECEMBER 18, 2024

According to a 2021 study by the Tufts Center for the Study of Drug Development, the average cost to develop a new drug is a staggering $2.6 A robust patent strategy often involves filing multiple applications at different stages of drug development. billion[1].

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European Pharmaceutical Review

MARCH 22, 2023

The technology is an additive manufacturing process which enables the development and production of complex formulations and geometrical structures of oral dosage forms to optimise the release profiles of common pharmaceuticals in addition to new drug developments.

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PharmaTech

APRIL 13, 2025

3D screen printing provides innovative drug development capabilities that are difficult or impossible to achieve with traditional methods, including complex multi-layered formulations, precision control over drug release profiles, and near-endless possibilities in the geometric shaping of dosage forms.

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Express Pharma

JANUARY 17, 2025

As environmental concerns continue to intensify, the pressure on the pharmaceutical industry to reduce its overall environmental impact, particularly in final dosage forms, is growing proportionately. Lonzas comprehensive sustainability approach spans the entire value chain, from raw material selection to end-of-life solutions.

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Dosage Pharmaceutical Manufacturing Packaging Drug Development 104

PharmaTech

JUNE 5, 2025

News All News Bio/Pharma News Publications All Publications PharmTech PharmTech Europe Resources Marketplace ICH Q9 Revision: A Comprehensive Resource on Quality Risk Management Peer-Reviewed Research PharmTech Products Pharma Insights Sponsored Podcasts Sponsored Videos Sponsored eBooks Whitepapers Webcasts Multimedia All Videos Ask the Expert Behind (..)

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Express Pharma

OCTOBER 19, 2023

The company informed that it is equipped to support the clinical manufacturing of a wide range of dosage forms, including oral solids, liquids, topicals, and films. We look forward to leveraging these capabilities to support our customers’ drug development needs, enabling them to bring life-changing medicines to patients worldwide.”

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BioPharma Dive

JULY 17, 2023

With this highly marketable dosage form, scientists can effectively formulate poorly soluble drugs and supplements, while reducing development time and costs.

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PharmaTech

JUNE 5, 2025

How the trade tariffs are fueling the shift back to oral solid dosage (OSD) products like tablets and capsules. Learn more about: Techceuticals and PharmParts, value-add businesses that focus on novel technologies, comprehensive training, and simplicity for CDMOs.

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Pharmaceutical Technology

JUNE 15, 2023

Drug development is already a difficult endeavor, with the vast majority of R&D efforts failing to produce a market-worthy product. Even reaching the clinical trial phase offers no guarantees, as only 12% of such drugs receive U.S. While this process is essential, it’s also slow, expensive and unpredictable.

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PharmaTech

JANUARY 7, 2025

This executive summary focuses on dose-flexible manufacturing strategies and their role in drug development. However, flexible dosing strategies are often neglected or not prioritized early in development.

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European Pharmaceutical Review

APRIL 9, 2024

The 31,600 square meter facility produces some 40 million finished solid dosage forms each year, including tablets, capsules and pellets. The acquisition will strengthen the CDMO’s position in the Netherlands, where it already owns a manufacturing facility in Bladel and an injectable drug development centre in Leiden.

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Pharmaceutical Manufacturing Dosage Drug Development 98

European Pharmaceutical Review

JUNE 29, 2023

Achievement of the first dose in human patients is a “milestone” for AI-driven drug discovery and drug development , stated Feng Ren, PhD, co-CEO and Chief Scientific Officer of Insilico Medicine. In February 2021, the small molecule drug INS018_055 started a first-in-human study for IPF in November 2021.

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Pharmaceutical Technology

DECEMBER 6, 2022

HPAPIs may now represent more than 30% of the drug development pipeline. Within that figure, GlobalData estimates that around 60% of pipeline HPAPIs are developed to target oncology. Nowadays, you have drugs against cancer which have a very high impact even at a very low dosage.”.

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European Pharmaceutical Review

JUNE 28, 2023

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved a first-of-its-kind trial to run this year to test psychedelic drugs as a treatment for major depressive disorder (MDD). The clinical trial will combine dosages of a new psilocin-based drug with specialist therapy.

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Quality Matters

MAY 17, 2023

Paradigm Shift in Drug Development: Analytical Quality by Design and Analytical Procedure Life Cycle In today’s pharmaceutical manufacturing environment, companies face increasing pressure to respond to changing demands across the global medicines supply chain while still maintaining the quality of their drug products.

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PharmaTech

NOVEMBER 5, 2023

To help improve adherence in children, drug developers need to consider innovative new dosage forms that can deliver flexible and convenient medications for young patients.

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PharmaTech

FEBRUARY 14, 2023

But to overcome the challenges of adherence in children, drug developers need to consider innovative new dosage forms that can deliver flexible and convenient medications for young patients.

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European Pharmaceutical Review

JUNE 28, 2022

Chromatography can be used throughout the drug development process, from the identification od potential drug candidates (with HPLC enabling high throughput screening) to ensuring drug formulation purity, analysing the bioavailability and release time of novel drug formulations to determine dosages to devising manufacturing techniques.

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FDA Law Blog: Biosimilars

APRIL 2, 2024

This proposal is clearly intended to address difficulties in formulating generic drugs with the same quantity and quality of inactive ingredients as required by regulation for certain dosage forms. “FDA FDA believes this change would effectuate timelier and more cost-efficient generic drug development.”

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Pharmaceutical Technology

SEPTEMBER 8, 2022

Pharmaceutical solid dosage forms are the most popular in the pharmaceutical industry and are one of the most used drug delivery methods across patient groups. Growth of oral solid dosage contract manufacturing in the pharmaceutical industry.

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Pharmacy Is Right For Me

APRIL 4, 2023

There are so many different types of careers within the field of pharmacy—from research and drug development to pharmacy informatics! And when the medication was delivered to her home, she realized the dosage no longer matched her regimen. This patient received a 30-day supply of insulin before discharge.

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pharmaphorum

JULY 13, 2022

The lack of measurability in neurological diseases plagues pharma every step of the way when it comes to drug development. Just recruiting for a trial of a drug that’s meant to intervene at an early stage of Parkinson’s or Alzheimer’s is difficult, because patients are almost never diagnosed until they’re symptomatic.

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Syner-G

SEPTEMBER 20, 2023

By: Mayuri Mutha, Senior Manager, CMC Development & Project Management Joseph Sclafani PhD, Director, CMC Development & Project Management Drug development is a complex, expensive, and multistage process which could take 10 to 15 years to bring a new molecule from discovery to commercialization.

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European Pharmaceutical Review

JANUARY 4, 2023

WuXi STA , a subsidiary of WuXi AppTec, has announced that its first continuous manufacturing ( CM ) line for oral solids is in operation at its drug product site in Wuxi city, China. A report has estimated that the oral solid dosage (OSD) contract manufacturing market will be valued at $54.7 Oral solids. billion by 2030.

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Express Pharma

APRIL 19, 2023

With a focus on optimising patient experience with next-generation oral dosage forms, the US facility complements the cutting-edge research activities of Roquette’s existing pharma innovation centers in France and Singapore. Expert training, troubleshooting and scale-up advice will be priorities at the facility.

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Pharmaceutical Technology

JANUARY 22, 2023

Nicklas Westerholm, the CEO and president of orphan drug developer Egetis Therapeutics, says disease awareness amongst paediatric neurologists and endocrinologists is low for MCT8 deficiency. The FDA will weigh the concerns and benefits of this drug before its PDUFA date in October.

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Communication Dosage Drug Development 126

Syner-G

JULY 7, 2023

It guarantees delivery of the right drug and the right dosage at precisely the right time , tailored specifically for that person. Drug developers must establish stable, robust, and cost-efficient manufacturing processes, especially for rare disorders with small patient populations and limited therapeutic options.

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European Pharmaceutical Review

JUNE 24, 2022

But what are the key potential changes and how could they impact drug developers and manufacturers? He noted that within the proposals, there is likely to be a differentiation in incentives for drug development in the orphan and unmet medical need areas. Key areas of potential legislative change. Future outlook.

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Pharmaceutical Technology

AUGUST 3, 2022

The potential to use these scientific breakthroughs to make a real difference to patients’ lives is what drives many highly skilled scientists to the world of drug development. Yet commercialising a drug is no easy journey, hence why just 10% of new drug candidates succeed in making it to market.

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Pharmaceutical Technology

SEPTEMBER 14, 2022

The dose form manufacturing follows API manufacturing to produce the final dosage form (FDF such as tablets and injectables. These companies offer services such as formulation development, process optimisation, analytical method development, qualification, validation and testing, regulatory guidance and several other solutions and products.

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pharmaphorum

OCTOBER 11, 2022

eligible dosages, how the drug is administered, and frequencies of drug intake). In the general case, RCTs are the optimal approach to clinical research and drug development. Various sophisticated methods are possible and sensitivity analyses should be applied to check on the robustness of results. Discussion.

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Viseven

AUGUST 15, 2024

The traditional model of drug development and healthcare delivery is undergoing a seismic shift, with patient engagement emerging as a critical factor in achieving better health outcomes and driving innovation. This change is further driven by major regulatory bodies emphasizing Patient-Focused Drug Development (PFDD).

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PharmaState Academy

OCTOBER 20, 2023

a) It has no impact b) It improves medication taste c) It simplifies dosage instructions d) It provides discounts on medications 9 / 20 According to a study in the Journal of General Internal Medicine, what percentage of patients feel rushed during doctor's appointments?

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Pharmaceutical Technology

FEBRUARY 13, 2023

Given the plethora of new chemical entity (NCE) candidates, pharmaceutical research groups frequently face challenges when selecting the most promising candidate for development purposes. With all this in mind, how do drug developers know which strategy and approach is right for their molecule at this early stage?

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Pharmaceutical Technology

FEBRUARY 13, 2023

This makes early R&D less risky, as many lead compounds are discontinued due to inadequate pharmacokinetic profiles and require excessively high dosages to be pharmaceutically active.

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Pharmaceutical Technology

JULY 18, 2022

Compaction simulation is arguably the most important when dealing with oral solid dosage forms. The single-punch tableting press enables drug developers to test formulations at full production speed, replicating the parameters of all types of industrial rotary press.

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Pharmaceutical Technology

FEBRUARY 21, 2023

For Skyepharma, a CDMO specialising in oral solid dosage forms, notable reductions in costly product waste was one advantage. Versatility Finding a versatile R&D tablet press is key for flexible drug development. Testing a formulation on MEDELPHARM’s single-punch tablet press required just 0.9kg of powder.

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