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STAT+: Drug may make chemotherapies less effective in cancer patients with obesity — but many doctors are in the dark

STAT

This means chemotherapies may be less effective when interacting with the medicine, but some clinicians, and their patients, are unaware of that possibility. A drug used to combat fungal infections in cancer patients comes with a big caveat — research shows the medicine can last twice as long as in people with obesity.

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STAT+: Jazz Pharmaceuticals to acquire Chimerix and its experimental brain cancer drug

STAT

It responds poorly to chemotherapy and is usually driven by a mutation that can’t be drugged with traditional approaches. The tumor, known as diffuse midline glioma, or DMG (and sometimes as DIPG depending on where it’s found), has flummoxed researchers for decades. Median survival is generally cited as less than a year. 

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Opinion: STAT+: Biotech investors: Stop expecting CRISPR science to make big leaps

STAT

An increasing challenge in the treatment of oral cancer is that tumors become resistant to chemotherapy. The medical promise of CRISPR gene editing can be seen most easily in current research on oral cancer, which affects more than 50,000 Americans every year.

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Study shows benefits of pharmacy sore throat service over GP consultation

The Pharmacist

The study, published in the Journal of Antimicrobial Chemotherapy, found that pharmacy-led sore throat treatment provides a safe, effective, and cost-efficient alternative to GP consultations. The research, […] The post Study shows benefits of pharmacy sore throat service over GP consultation appeared first on The Pharmacist.

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Asahi Kasei Pharma starts Phase III study of CIPN prevention therapy

Express Pharma

Asahi Kasei Pharma has started trial drug administration in a Phase III study of ART-123 in Japan (generic name: thrombomodulin alfa; marketed as Recomodulin Injection in Japan) for the prevention of chemotherapy-induced peripheral neuropathy (CIPN) related symptoms.

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USC-licensed startup NeOnc Technologies gets NASDAQ listing

Express Pharma

This is different from traditional chemotherapy which is usually given orally and intravenously. The molecule were delivering is inhaled through the nose, crosses the nasal passage, interacts with the olfactory nerve and then enters the cerebrospinal fluid and circulates throughout the brain.

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STAT+: Pharmalittle: We’re reading about a Merck drug-label controversy, Astellas pulling an application, and more

STAT

This means chemotherapies may be less effective when interacting with the medicine, but some clinicians, and their patients, are unaware of that possibility , STAT explains. The information, however, is not in the label because the drug — originally manufactured by Merck — was never fully tested in this population.

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