Trending Articles

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Opinion: Measles is coming back. My sister Marcie isn’t

STAT

At the end of February 1960, my healthy, precocious sister Marcie was halfway through the fourth grade when she contracted measles from a classmate who lived down the street. Their cases were among the nearly 500,000 that year , before the measles vaccination program began in the U.S. in 1963. For every 1,000 people who get measles, one develops measles encephalitis , which can cause permanent brain damage.

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As drug shortages reach record highs, regulators float next steps

PharmaVoice

With many chemo and ADHD drugs stuck in stubborn shortages, several agencies are looking for new solutions to boost supplies.

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As AI proliferates in pharma, regulators look to catch up in clinical trials

PharmaVoice

The FDA’s newly launched Center for Clinical Trial Innovation potentially opens the door for more efficient and expanded AI use, but leaves pharmas wanting more guidance.

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Hot off the press: Bridge to EM curriculum (2nd edition) released

ALiEM - Pharm Pearls

It has been 3 years since the 8-week, self-guided Bridge to Emergency Medicine (EM) curriculum was launched to help graduating medical students prepare for EM residency. The curriculum has been viewed over 43,000 times and we have awarded over 5,000 ALiEMU course certificates. It is now a part of many residency programs’ intern boot camp. Launching the 2nd edition of Bridge to EM (2024) We are thrilled to announce that we launching the second edition of the curriculum.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Revealed: key files shredded as UK government panic grew over infected blood deaths lawsuit

The Guardian - Pharmaceutical Industry

Lost documents prevented victims from finding out the truth, official inquiry told Disastrous failures that caused the contaminated blood scandal were denied by ministers for decades after officials destroyed, lost and blocked access to key documents, memos submitted to the official inquiry reveal. Several batches of files involving the work of a blood safety advisory committee were shredded as the government faced the threat of legal action, documents show.

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Can a Device Be Found Not Substantially Equivalent Because of Cybersecurity Risks? A Review of FDA’s Draft Guidance on Cybersecurity in Medical Devices

FDA Law Blog: Biosimilars

By Lisa M. Baumhardt, Senior Medical Device Regulation Expert & Adrienne R. Lenz, Principal Medical Device Regulation Expert — FDA recently issued a draft guidance which would update the agency’s Cybersecurity in Medical Devices: Quality System Considerations and Content of Premarket Submissions guidance. The draft guidance provides recommendations on what is required to meet cybersecurity obligations under section 524B of the Food, Drug and Cosmetic Act (FD&C).

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AstraZeneca admits Covid-19 vaccine may cause blood clots in “very rare” cases

Pharmaceutical Technology

AstraZeneca has maintained that while the vaccine may, in “very rare” cases, cause TTS, the casual mechanism for this effect remains unknown.

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Prevention revolution: How digital tools can help us get ahead of health problems

pharmaphorum

Discover how digital tools can provide insights to help us. Digital technology could be a game-changer that offers the elusive promise of tackling the root cause, not just the conditions themselves, when it comes to human health.

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Bluebird preps for first commercial use of sickle cell gene therapy

BioPharma Dive

A 12-year-old boy in the Washington, D.C., area is set become the first patient treated with Lyfgenia since its U.S. approval last December.

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STAT+: Alzheimer’s risk gene APOE4 may cause a distinct form of the disease, study suggests

STAT

For more than 30 years, Alzheimer’s researchers have thought of APOE4 as a major genetic risk factor for most cases of the devastating neurologic disease. But a new study published on Monday argues that this gene variant plays an even more important role than scientists had realized and causes a distinct form of Alzheimer’s. Researchers analyzed data from more than 13,000 people, including nearly 800 APOE4 homozygotes, people who carry two copies of the gene variant.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Takeover target? Activist investor believes Novavax tech would be in ‘better hands’ with Big Pharma

PharmaVoice

With its next earnings report looming, pushback from an investor is adding pressure on Novavax to boost performance.

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Latus Bio secures $54m for CNS gene therapy development

Pharmaceutical Business Review

The financing round is co-led by 8VC and DCVC Bio, with contributions from Samsung Life Science Fund, The Children’s Hospital of Philadelphia Foundation, Benjamin Franklin Technology Partners, Modi Ventures, and Gaingels. Latus Bio, emerging from the lab of co-founder professor Beverly Davidson at the Children’s Hospital of Philadelphia, is utilising proprietary technologies to develop CNS gene therapy candidates.

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Boehringer will use Walgreens trials unit for obesity trial

pharmaphorum

Walgreens’ plans to disrupt the clinical trials sector have taken a step forward with a high-profile partnership with Boehringer Ingelheim

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Amgen shares soar as executives outline obesity drug push

BioPharma Dive

The company said data for its Wegovy competitor was promising enough to move the drug into late-stage testing, triggering a stock jump that added billions to Amgen’s market value.

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WHO’s top scientist learned a hard lesson about H5N1 two decades ago: Stopping it takes more than biology

STAT

Jeremy Farrar, now the World Health Organization’s chief scientist, was working in Vietnam 20 years ago when the H5N1 virus started to spread across Asia — at that point in poultry. He recalls there was a reluctance among farmers to cull their chickens because they weren’t being compensated for them. Movement of infected birds to evade culling only served to disseminate the virus, which in the years since has spread to all continents except Australia.

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Bayer secures full ownership of Bayer Zydus Pharma, acquires remaining 25 per cent stakes

Express Pharma

Bayer Pharmaceuticals and Zydus Lifesciences announced the successful conclusion of their joint venture (JV) – Bayer Zydus Pharma. The 50:50 joint venture was established on January 28, 2011, for the sales and marketing of pharmaceutical products in India. Bayer is now securing full ownership of the entity, as per pre-agreed JV terms. A press statement from Bayer informed, “The JV successfully leveraged the strengths of both companies to better serve the fast-growing Indian market.

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Have your say on PCN pharmacy and you could win a £200 voucher

The Pharmacist

Together with our sister publications, The Pharmacist has launched a survey to hear what pharmacists think about the last five years of change in primary care. The State of Primary Care Survey asks how the changes to the NHS — the launch of primary care networks (PCNs) in 2019 and the shift to integrated care systems (ICSs) in 2022 […] The post Have your say on PCN pharmacy and you could win a £200 voucher appeared first on The Pharmacist.

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Activist investor urges changes to Novavax board

pharmaphorum

Shah Capital has stepped up its campaign for change at vaccine producer Novavax, lobbying against the re-election of three directors and executive pay packages in a letter to fellow stockholders. The hedge fund says it wants to send a “strong and clear message” to the board at Novavax, reiterating the claim – first made a few weeks ago – that the company is “being hindered by an overly conservative board and management that clings to failed strategies.

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Reunion raises over $100M to build a better psychedelic drug

BioPharma Dive

The funding will help Reunion pay for a mid-stage study testing its most advanced medicine — essentially a synthetic version of the hallucinogenic psilocin — in women with postpartum depression.

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Meet the scientist sending tumors into space

STAT

What happens when you catapult cancer into space? Or shoot stem cells toward the stars? Catriona Jamieson, a hematologist and director of the Sanford Stem Cell Institute at the University of California, San Diego, has done both. Through collaborations with organizations like NASA, her lab has sent tumors and stem cells aboard private spaceflights like SpaceX CRS-24 and the recent Axiom-3 mission to be studied in the International Space Station.

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Angle signs AstraZeneca deal to develop prostate cancer assay

Pharmaceutical Technology

UK liquid biopsy company, Angle, has agreed a supplier agreement with AstraZeneca to develop a Parsotix-based Androgen Receptor (AR) assay for use in prostate cancer studies.

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Sharp spike in pharma, healthcare funding in April 2024, touches $332 mn

Express Pharma

API Holdings secured the biggest deal ($216 million), followed by La Renon ( $70 million) and Biodeal Pharmaceuticals ($13.2 million). Funding was raised by 291 per cent for the sector in April 2024, 1045 per cent higher than the same month last year ($29 million) , accounting for $332 million, over 15 rounds in total. As per the data presented by Tracxn.com, API Holdings secured the biggest deal by raising $216 million in healthcare, healthtech and life sciences.

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Pace, acceleration, and precision are the name of the game

pharmaphorum

Security and privacy within biotech are critical points of consideration and discussion as the industry continues to innovate at speed, and it is such aspects that are central to today’s podcast with Zach Powers, chief information security officer at Benchling, the R&D cloud platform for the biotech industry.

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GSK raises forecasts on strong vaccine, HIV drug sales

BioPharma Dive

Sales of the shingles vaccine Shingrix and the RSV shot Arexvy helped fuel quarterly revenue totals that surpassed analyst expectations, though the company warned momentum could slow in the months ahead.

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CDC’s top flu scientist says the risk to the public from H5N1 is low, but she isn’t sleeping well. Here’s why

STAT

Vivien Dugan isn’t getting much sleep these days. The director of the influenza division at the Centers for Disease Control and Prevention, Dugan is leading the team of CDC scientists that is working with partners — in the U.S. Department of Agriculture, the Food and Drug Administration, and state and local health departments — to respond to the H5N1 bird flu outbreak in dairy cattle.

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Final April price concessions published by DHSC

The Pharmacist

The Department of Health and Social Care (DHSC) has published its final list of price concessions for April 2024. The final update comes after the end of month and follows concerns raised by Community Pharmacy England (CPE) over potential delays to concessions announcements adding ‘another layer of complexity’ to the process. The first April price […] The post Final April price concessions published by DHSC appeared first on The Pharmacist.

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SSRIs In Pregnancy

Med Ed 101

Depression is one of the top three health disorders in adults ages 18-34 with approximately 21.3% of these adults having depression. This means that many women suffer from depression during their peak childbearing years and will begin medication to treat it. Uncontrolled depression or anxiety may lead to issues in pregnancy. Thus, there is always […] The post SSRIs In Pregnancy appeared first on Med Ed 101.

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Top charities team up with $300m for climate, health equity

pharmaphorum

The Novo Nordisk Foundation, the Bill & Melinda Gates Foundation, and Wellcome have joined forces to tackle some of the most pressing threats to human health and wellbeing. The new initiative gets underway with $300 million in funding over three years earmarked for handling infectious diseases and antimicrobial resistance (AMR), addressing climate change, and raising our understanding of how nutrition can impact immunity, disease, and the development of children.

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Pfizer’s strong Vyndaqel sales draw attention to rare disease drug’s patent life

BioPharma Dive

Sales of the transthyretin amyloidosis treatment widely beat Wall Street forecasts in the first quarter. The company aims to extend its patent exclusivity.

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Texas dairy farm worker’s case may be first where bird flu virus spread from mammal to human, scientists say

STAT

A new report on the first human bird flu case tied to the outbreak in cows in the United States suggests that the Texas man may be the first detected case of the H5N1 virus transmitting from a mammal to a person. Nearly 900 people in 23 countries have been infected with the H5N1 bird flu virus since it started spreading from Southeast Asia in late 2003.

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From banking to biotech - Renée Aguiar-Lucander's unique path in science

Outsourcing Pharma

RenÃe Aguiar-Lucander, CEO of Calliditas, is driving the advancement and launch of TARPEYO â the companyâs medication targeting rare disease IgA nephropathy. We spoke with RenÃe about her journey from investment banking to science and the joy of bringing therapies to patients.

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Pharmacy concerns after data reveals drop in Welsh GP practices

The Pharmacist

A decline in the number of GP practices in Wales has prompted the Royal Pharmaceutical Society (RPS) to call for government investment, amid concern over the ability of pharmacists working in general practice to deliver high-quality care. Official figures show there were 374 active GP practices in Wales at the end of 2023, which represents […] The post Pharmacy concerns after data reveals drop in Welsh GP practices appeared first on The Pharmacist.

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MHRA ‘sandbox’ to pilot AI regulation will go live soon

pharmaphorum

The MHRA's regulatory sandbox for artificial intelligence as medical device technologies, AI-Airlock, will go live this spring, according to a new strategy document

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Novartis to buy Mariana Oncology in radiopharmaceutical expansion

BioPharma Dive

The $1 billion dollar acquisition will add to Novartis’ pipeline of the targeted radiation drugs, giving it a potential lung cancer treatment.

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Opinion: An AI-based second opinion service could improve clinical decision-making today

STAT

Millions of Americans rely on the internet to answer questions about their own health. The public release of powerful artificial intelligence models like ChatGPT has only accelerated these trends. In a large survey , more than half of American adults reported putting their own health information into a large language model (LLM). And there’s reason to believe these models might bring real value to these people, such as the case of a mother who, after seeing 17 physicians and receiving no

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