BioPharma Dive

AUGUST 11, 2025

GoodRx research shows an average 39% list price increase for all prescription medications since 2014, and in 2024 Americans paid $61 billion in OOP costs for their prescription medications. Formulary designs continuously evolve and formulary exclusions and other restrictions increase each year, increasing patients’ cost burden.

Drug Pricing

ALiEM - Pharm Pearls

NOVEMBER 1, 2023

 Deferoxamine binds with ferric iron (Fe3+) to form ferrioxamine, a water-soluble compound excreted in the urine. As Intensive Care Med 2014; 40(1):104. PMID Iron toxicity treated with deferoxamine Background Deferoxamine is the treatment for severe iron toxicity [1]. Deferoxamine Treasure Island (FL): StatPearls Publishing; 2023 Jan–.

Clinical Pharmacology

pharmaphorum

NOVEMBER 29, 2022

By enabling strong CD8 T-cell infiltration in cold tumor tissues, NT-I7, a compound developed by NeoImmuneTech, is capable of promoting a microenvironment that contributes to clinical efficacy, when combined with a CPI. Dr Se Hwan Yang, PhD, President and Chief Executive Officer, founded NeoImmuneTech in January 2014. Creation: Jan.

Immunization

pharmaphorum

JULY 8, 2021

Hoos is leaving GSK after nine years, a period that saw a complete revamp of the unit including the wholesale divestment of cancer drugs to Novartis in a $16 billion deal announced in 2014 – which completed as he took over the division.

Compounding

European Pharmaceutical Review

DECEMBER 21, 2022

Although some psychedelics have a long history in traditional medicine, regulatory agencies must evaluate psychedelic compounds the same way they assess any other drug. Psychedelic compounds are assessed by regulators the same way as any other drug. Expediated pathways available for psychedelics.

Compounding

European Pharmaceutical Review

JULY 13, 2023

While this is essential in the interrogation of novel compounds for which we know very little about their efficacy and safety, it is also true that some biomedical research is highly wasteful. 3 Moreover, some studies have suggested that co-administration of these compounds can modulate the effects of one another at a receptor level.

Compounding

Pharmacy Joe

OCTOBER 25, 2023

The removal appears to be in response to the publication of a 2021 article in the International Journal of Pharmaceutical Compounding. The list was originally compiled and updated by John Mitchell, PharmD, who passed away on June 10, 2014.

Dosage

PharmD Live

MAY 30, 2024

The side effects can compound, resulting in a greater negative impact on a patient’s health than the individual effects of one medication alone. US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014. Adverse Drug Reactions (ADRs) Adverse drug reactions are a major concern in polypharmacy. Campbell, N.

Clinical Pharmacology

RX Note

MARCH 23, 2023

Today, stability information can be obtained from manufacturer’s labelling information (such as in the package insert), the USP compounding monographs, or peer-reviewed articles and references , such as articles in American Journal of Health-System Pharmacy, the International Journal of Pharmaceutical Compounding.

Compounding

Express Pharma

JUNE 28, 2024

In 2014, the market size for Ayurveda products was around $3 billion. He shared that this growth is underpinned by robust regulatory frameworks, often mirroring US standards and a holistic approach to isolating compounds in traditional medicines. By 2021, a survey revealed the market size had surged to $18.2

Hospitals

pharmaphorum

MAY 7, 2021

For nearly 25 years, Jeremy has focused on aiding the biopharmaceutical and health sciences industry in the development of key compounds and new therapies. He has been reporting on the pharma industry since 2014 and has worked at a number of leading publications in the UK. About the interviewee. Jeremy Edwards is CEO of Xperiome.

Drug Development

RX Note

JULY 8, 2023

Typically, new drugs are discovered through new insights into a disease process, unanticipated effects of existing treatment and tests of many novel molecular compounds. Lead optimization studies are carried out to identify compounds with the "best" properties (activity, toxicity, pharmacokinetic, physiochemical, etc.)

Drug Development

PharmaShots

FEBRUARY 22, 2023

In the US, Trulicity is protected by a compound patent (2027) and by biologics data protection (2026). million patients’ journeys with type 2 diabetes since 2014. Active Ingredient: dulaglutide Dosage Forms & Strengths: Injection: 0.75 mL, 3 mg/0.5 Trulicity has been a part of over 2.8

Diabetes

RX Note

JANUARY 21, 2023

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)

Compounding

The Thyroid Pharmacist

AUGUST 18, 2023

Benefits and Uses of Curcumin Turmeric’s medicinal benefits can mostly be attributed to compounds called curcuminoids. Combining curcumin with piperine, an alkaloid found in black pepper, extends the life of curcumin in the body, making its compounds more therapeutically effective. 2014 Jul;69:182-201 [2] Prasad S, Aggarwal BB.

Dosage

Eye on FDA

AUGUST 2, 2022

And since 2014 the Office of Prescription Drug Promotion (OPDP) has broken double digits only 3 times, producing only 6 letters in both 2020 an 2021. The characterization of investigative data resulted in a violation related to promotion of an unapproved compound. In 1998, there were 156 letters issued in a single year.

Communication

pharmaphorum

JUNE 7, 2022

The Hong Kong-based startup – one of an emerging crop of companies which are using artificial intelligence platforms to discover and design new therapeutic compounds – took its first drug into clinical trials in February.

Compounding

pharmaphorum

JULY 9, 2014

The global pharmaceutical market passes a significant milestone in 2014: reaching one trillion US dollars in total value.

Compounding

RX Note

JUNE 5, 2023

Workplace activity involves how healthcare workers use and handle the drug in the workplace - such as opening shipments, compounding, administering or cleaning up after use or spills. Oral hazardous drugs No crushing or compounding may be done in an unprotected environment. Consider having spill-response exercises or drills.

Compounding

pharmaphorum

JANUARY 9, 2023

It also has potential in NDD, although it was discontinued as a treatment of fragile X syndrome in 2014 after disappointing phase 2b trial results. The market potential of the CUD and NDD indications alone could top 2 billion euros ($2.12 billion) globally, the company noted. Lynn Durham.

Compounding

pharmaphorum

JANUARY 8, 2021

According to the figures compiled in the third quarter of last year, pharma brands were projected to spend around $10 billion in 2020 on digital advertising aimed at all groups including doctors, a compound annual growth rate of more than 13% since 2014.

Communication

European Pharmaceutical Review

JANUARY 18, 2024

Insomnia market Dual orexin receptor antagonists (DORAs) [dual orexin receptor antagonists (DORAs)]… offer a new mechanism of action [in treating insomnia]” Across the seven major markets, the insomnia market is anticipated to grow at a compound annual growth rate (CAGR) of 2.6 percent from $3.2 billion in 2022 to $4.1

Drug Pricing

Pharmaceutical Technology

JANUARY 23, 2023

Out of the seven biologics approved to treat moderate to severe CD in adults, only the anti-TNFαs, Remicade (infliximab), and Humira (adalimumab), have been approved for paediatric patients, with Humira receiving the most recent approval in 2014.

Labelling

European Pharmaceutical Review

SEPTEMBER 25, 2023

NMR relaxation methods distinguish between components (phases or compounds) that have different molecular mobilities For monoclonal antibodies, identification methodologies can employ chromatography, spectroscopy, isoelectric focusing, capillary electrophoresis and peptide mapping techniques. 2014; 53(48): 7515–22. Chromatography.

Compounding

European Pharmaceutical Review

DECEMBER 21, 2022

Organic compounds are arguably the foundation of the pharmaceutical industry. All traditional small molecule pharmaceuticals include carbon building blocks” Organic compounds are arguably the foundation of the pharmaceutical industry. Chem Commun 2014, 50, 9650‒9652. Org Process Res Dev 2022, 26, 9, 2685–2693.

Compounding

pharmaphorum

JANUARY 23, 2023

AbbVie paid Morphic $100 million upfront to claim a share of the programme in 2018, and stumped up another $20 million to opt into specific compounds in 2020, but pulled out altogether last year. The collaboration was focused on development of alpha V beta 6 drugs for fibrotic diseases, including idiopathic pulmonary fibrosis (IPF).

Compounding

pharmaphorum

JANUARY 18, 2021

This has been compounded with the looming spectre of Brexit, which has meant the NHS lost some of its valuable workforce from overseas. Karina founded Acumentice in 2014, with a view to share this expertise through the development of clear and sustainable methodologies and frameworks.

Compounding

The Happy PharmD

OCTOBER 28, 2024

billion in revenue by 2014, it paled in comparison to the colossal figures of CVS and Walgreens, which raked in $139 billion and $76 billion, respectively. Target’s overall profit margins were low, compounded by costly operational issues and the aftermath of shutting down its Canadian operations, which resulted in a $2.5

Compounding

Pharmacy Joe

OCTOBER 25, 2023

The removal appears to be in response to the publication of a 2021 article in the International Journal of Pharmaceutical Compounding. The list was originally compiled and updated by John Mitchell, PharmD, who passed away on June 10, 2014.

Dosage

pharmaphorum

JANUARY 27, 2023

An additional note of optimism is that UK biotechs achieved pivotal milestones in their development, with Verona Pharma reporting a successful phase 3 trial for Ensifentrine, the first novel compound in over 10 years to address the ongoing needs of more than 380 million patients worldwide suffering from Chronic Obstructive Pulmonary Disease (COPD).

Compounding

RX Note

JUNE 5, 2023

Phenylketonuria Risk Aspartame is catabolized to phenylalanine among other compounds, making it unsafe for consumption in individuals with phenylketonuria. Stability at High Temperature Aspartame is unstable at high temperatures and cannot be used for baking or cooking.

Packaging

The Pharmacist Blog

MARCH 28, 2015

compound interest with higher debt working against the pharmacist not accounted for). missed opportunity for compound interest). missed opportunity for free money and compound interest). Key take aways: save early, invest early, compound interest is your friend, minimize debt, live smart, and avoid being sucked into consumerism.

Pharmacy Technician

European Pharmaceutical Review

FEBRUARY 28, 2023

Pathways for N-Nitroso Compound Formation: Secondary Amines and Beyond. 1,2 Of the limited number of N -nitrosamines in the Lhasa Cancer Potency Database (LCPD), less than four percent are NDSRIs. EMA/409815/2020 Rev.13. López-Rodríguez R, McManus JA, Murphy NS, et al. Org Proc Res Dev. 2020; 24(9): 1558–1585. Cross KP, Ponting DJ.

Compounding

pharmaphorum

FEBRUARY 18, 2021

Eli Lilly’s Humalog compound and formulation patents expired in 2013 and 2014, respectively. The history of insulin captures one of the mystifying complexities of the pharmaceutical market — how long-standing drugs become more expensive with time and competition fails to hold down prices.

Prescription Filling

European Pharmaceutical Review

JULY 4, 2024

The intricate nature of botanical products further compounds the challenge, demanding a paradigm shift in regulatory interpretation and QC standards. In the UK, the dichotomy between traditional herbal registration and MA delineates the regulatory framework for herbal medicines, catering to both minor and major health conditions.

Drug Development

Quality Matters

MARCH 1, 2024

USP has a long-standing history of healthcare standards including those for compounding preparations that are tailored to meet the unique needs of patients who may not otherwise have access to their medications. Washington (DC): 2014; pharmacogenomics working group whose mission is to develop a 56. Nature 520, 609–611 (2015).

Labelling

The Thyroid Pharmacist

NOVEMBER 4, 2022

While the human body (via the liver and kidneys) can produce up to 4 g/day of inositol, it has been found that the overly processed, high glucose (and low fiber) Western diets that many people follow, only provide about 1 g/day of the compound. (7). 2014 Jan;29(1):55-63. Recommended Dosage and Precautions. Int J Endocrinol.

Diabetes