Pharmaceutical Technology

OCTOBER 14, 2022

In 2016, the companies entered a strategic partnership to develop novel messenger RNA (mRNA) based PCVs. The mRNA-4157/V940 has been designed to stimulate an immune response by producing T-cell responses depending on the mutational signature of a patient's tumour.

Vaccines 115

Vaccines Research Laboratories Immunization Immunity 115

pharmaphorum

JANUARY 27, 2022

The first patient has been treated with an implantable bioelectronic device developed by Galvani Therapeutics, set up by GlaxoSmithKline and Alphabet’s Verily Life Sciences in 2016. Galvani is using its device to stimulate the splenic nerve, which sends signals to the spleen.

Immunization 110

Immunization Immunity 110

European Pharmaceutical Review

AUGUST 9, 2023

While injectable biologic therapies are an effective option for CSU that is uncontrolled by these drugs, less than 20 percent of patients worldwide are treated with them, according to a 2016 British Journal of Dermatology paper and research shared by Novartis. In REMIX-2, the clinical trial enrolled 455 participants with CSU.

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Immunization Immunity Pharmaceutical Companies Pharmaceutical Companies 94

European Pharmaceutical Review

DECEMBER 1, 2022

In order to speed up the regulatory process for advanced medicinal therapy products (ATMPS), the European Union (EU) implemented the priority medicines (PRIME) scheme in 2016. Since the COVID-19 pandemic, there has been a spike in interest in mRNA therapeutics, due to the success of mRNA vaccines treating the virus, observed GlobalData.

Vaccines 98

Vaccines Immunization Immunity 98

European Pharmaceutical Review

JANUARY 26, 2023

CAR T-cell therapy engineers a patient’s own immune cells (T-cells) to detect, target and destroy cancer cells. Could CAR T therapies be manufactured in one day?

Chemotherapy 124

Chemotherapy Immunization Immunity 124

pharmaphorum

JANUARY 7, 2022

Sanofi and Exscientia first started working together in 2016, initially on a fairly small-scale programme focused on bispecific small-molecule drugs for metabolic diseases, with a total value of around $275 million. The French drugmaker is paying $100 million upfront in the deal, but the total value could swell to a massive $5.2

Immunization 110

Immunization Immunity 110

European Pharmaceutical Review

AUGUST 26, 2022

Moderna has filed patent infringement lawsuits alleging that Pfizer and BioNTech’s COVID-19 vaccine Comirnaty ® infringes patents Moderna filed between 2010 and 2016 covering its foundational messenger RNA (mRNA) technology. ” But why sue now?

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Vaccines Immunization Immunity 98

European Pharmaceutical Review

DECEMBER 20, 2022

This technology is creating an entirely new class of molecules to induce synthetic immunity against cancer by harnessing NK cell effector functions against cancer cells and also providing proliferation and activation signals targeted to NK cells. Building on Sanofi’s and Innate Pharma’s original license agreement.

Immunization 98

Immunization Immunity 98

The Thyroid Pharmacist

JUNE 30, 2023

However, low doses of this medication (hence, low dose naltrexone or LDN), have been found to modulate the immune system and have shown promise in improving cases of autoimmune disease. These include Crohn’s, MS, and Hashimoto’s, as well as other immune system-related conditions such as cancer and HIV/AIDS. Doses of 1.5-4.5

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Compounding Immunization Immunity Compounding Pharmacies 98

pharmaphorum

SEPTEMBER 2, 2020

Vopratelimab is a monoclonal antibody that binds to and activates the Inducible T Cell CO-Stimulator (ICOS), a protein on the surface of certain T cells that is believed to stimulate an immune response against a patient’s cancer. In 2016 Celgene signed a $2.6

Immunization 71

Immunization Immunity 71

pharmaphorum

JUNE 9, 2021

After transplant, the 10 subjects in the study will take immunosuppressant drugs to prevent their immune system from rejecting the transplant. They will be followed up for two years, looking at safety, tolerability, the survival of the cells and the impact on Parkinson’s symptoms, with final results due in November 2023.

Immunization 91

Immunization Immunity 91

European Pharmaceutical Review

JUNE 13, 2023

In IgAN, autoimmune reaction to an abnormal form of IgA results in formation of immune complexes that deposit in the kidney. These immune complexes trigger inflammation and kidney damage. This then leads to progressive loss of renal function, according to a 2016 paper published in Nature Reviews Disease Primers. The post £2.5b

Immunity 52

Immunity Immunization 52

European Pharmaceutical Review

SEPTEMBER 5, 2024

2 These are cells commonly found in the stroma of the tumour, which play an important role in inhibiting the body’s own immune response to the tumour, mediated through CD8+ T-cells (tumour-infiltrating lymphocytes). Research in the last few years has shown NOX4 in tumour cells is linked to the growth of cancer-associated fibroblasts (CAFs).

Immunity 59

Immunity Immunization Diabetes 59

Pharmaceutical Technology

FEBRUARY 8, 2023

Since 2016, the facility has been manufacturing lentiviral vectors (LVV) and drug product for the ongoing programmes of Genenta. Under the deal, AGC Biologics will be responsible for manufacturing the cell therapy lentivirus-based product for the ongoing clinical programmes of Genenta Science.

Immunization 52

Immunization Immunity 52

The Thyroid Pharmacist

DECEMBER 28, 2022

Vitamin D supports the immune system by enhancing the pathogen-fighting effects of white blood cells, which are important parts of immune defense. Supplementing with vitamin D can especially help to improve mood and cognitive function during the winter months, as well as improve immune function. I recommend doses of 1.5

Immunization 111

Immunization Immunity Clinical Pharmacology Doctor of Pharmacy 111

pharmaphorum

JANUARY 6, 2023

While cTTP represents a tiny patient population for TAK-755, Takeda is also running trials of the drug in other indications, including a phase 2 study in acquired or immune-mediated TTP (iTTP) and phase 1 in sickle cell disease (SCD), which if positive could expand the number of patients eligible for treatment.

Immunization 59

Immunization Immunity 59

pharmaphorum

JUNE 26, 2025

Skip to main content Thursday 26 June 2025 BlueSky linkedin youtube rss User account menu Subscribe Channels Channels Digital Market Access Oncology Patients R&D Sales & Marketing Spotlight on Content type Content type Digital -News -Views & Analysis -Deep Dive -Webinars -Podcasts -Video -White Papers -Event Market Access -News -Views & (..)

Diabetes 59

Diabetes Pharmaceutical Companies Pharmaceutical Companies Biosimilars 59

pharmaphorum

JULY 1, 2025

billion, expanding its pipeline with a potential first-in-class treatment for autoimmune diseases as well as adding a novel RNA delivery system to its portfolio. billion, expanding its pipeline with a potential first-in-class treatment for autoimmune diseases as well as adding a novel RNA delivery system to its portfolio.

Diabetes 66

Diabetes Pharmaceutical Companies Pharmaceutical Companies Immunization 66

pharmaphorum

MARCH 11, 2022

For now, people in England without COVID symptoms can order one pack of seven LFTs every three days – previously it was one per day – until free access ends at the end of the month for anyone aged under 75 or with weakened immune systems. The situation isn’t clear in other areas of the UK.

Immunization 59

Immunization Immunity 59

The Thyroid Pharmacist

MAY 15, 2025

Additionally, high blood sugar can impair immune function, making it harder for the body to fight off infections. Takeaway Supporting a healthy gut microbiome may help reduce UTIs and also promote better thyroid function and immune balance in autoimmune conditions! August 22, 2016. Pediatr Res. 2023;93(4):1096-1104. Nature News.

Immunization 59

Immunization Immunity Labelling Compounding 59

pharmaphorum

MARCH 29, 2021

We are even at a point where some cancer medicines are created for each individual patient using their own immune system. “We have gone from making drugs for breast cancer to making drugs that are targeted to just specific types of breast cancer that express certain genetic markers.

Drug Development 93

Drug Development Immunization Immunity 93

pharmaphorum

SEPTEMBER 22, 2020

The biotech’s R&D focus has been on inflammasomes – intracellular groups of proteins that act as part of the innate immune system to respond to pathogens but can also run amok and cause inflammatory diseases.

Immunization 59

Immunization Immunity 59

RX Note

FEBRUARY 2, 2023

After primary infection, 90% of individuals with intact immunity control further replication control of the bacilli, which may then be cleared or enter a "latent" phase. Introduction Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis and is transmitted primarily by inhalation.

Immunization 52

Immunization Immunity Hospitals 52

European Pharmaceutical Review

FEBRUARY 22, 2023

Of the 175 new drugs approved by the US Food and Drug Administration (FDA) between 2016 and 2019, most were biologics. Biologics represent an increasingly large part of the pharmaceutical industry. 2 Most biotherapeutics are delivered parenterally, with some exceptions being ocular or inhaled formulations.

Biosimilars 105

Biosimilars Diabetes Immunization Immunity 105

pharmaphorum

JUNE 26, 2025

Skip to main content Thursday 26 June 2025 BlueSky linkedin youtube rss User account menu Subscribe Channels Channels Digital Market Access Oncology Patients R&D Sales & Marketing Spotlight on Content type Content type Digital -News -Views & Analysis -Deep Dive -Webinars -Podcasts -Video -White Papers -Event Market Access -News -Views & (..)

Vaccines 71

Vaccines Diabetes Pharmaceutical Companies Pharmaceutical Companies 71

European Pharmaceutical Review

OCTOBER 5, 2023

LNPs offer advantages such as reduced toxicity compared to adenovirus-based delivery methods, simplified manufacturing processes, and avoidance of immune responses and preexisting neutralising antibody issues. Prior to her role at AskBio, Sheila co-founded Bamboo Therapeutics and served as CEO until its acquisition by Pfizer in August 2016.

Immunization 104

Immunization Immunity 104

European Pharmaceutical Review

AUGUST 22, 2022

based vaccine technology to tackle diseases beyond COVID-19, such as influenza, cancer and AIDS (Acquired Immune Deficiency Syndrome), among others. Moving forward, biopharma companies are exploring the possible extension of the platform?based threatening diseases in the near future. Platform technologies for modern vaccine manufacturing.

Vaccines 98

Vaccines Immunization Immunity 98

The Thyroid Pharmacist

AUGUST 19, 2022

8) In very simple terms, this theory hypothesizes that our immune system begins to attack our own thyroid gland because we are infected with a pathogenic organism (like a bacterium, parasite , or virus ), that looks similar to components of the thyroid gland. Molecular mimicry is one of the leading theories of autoimmune disease. (8)

Health and Personal Care Stores 98

Health and Personal Care Stores Immunization Immunity Dosage 98

National Association of Boards of Pharmacy

OCTOBER 5, 2022

I have been a pharmacist for eight years, working in a community pharmacy, and have worked in the District of Columbia since 2016. We have been reviewing each chapter of the District of Columbia’s Pharmacy Laws and Regulations , which include pharmacist-in-charge requirements, immunizations, 90-day refills, and tech-check-tech.

Pharmacy Technician 52

Pharmacy Technician Community Pharmacies Communication Immunization 52

The Thyroid Pharmacist

NOVEMBER 4, 2022

12) For anyone looking to support immune health, hormone balance, and metabolic health, in addition to their thyroid, this is a great option. (37-39) doi:10.1155/2016/9537632. doi:10.1155/2016/1849162. doi:10.1155/2016/3204083. Brain Behav Immun. The influence of selenium on immune responses. 2012.01.006.

Diabetes 98

Diabetes Dosage Compounding Immunization 98

RX Note

AUGUST 4, 2023

Apart from Malaysian Clinical Practice Guidelines , other recommended local references include: ADR Reporters Guide Ampang Protocol, 2012 Anticoagulation MTAC Protocol, 2020 Antidote Quick Guide, 2022 Cancer Drug Counselling A Guide for Pharmacist, 2017 Clinical Pharmacokinetics Pharmacy Handbook, 2019 Code of Ethics for Pharmacists, 2018 Critical (..)

Hospitals 52

Hospitals Inpatient Community Pharmacies Dosage 52

pharmaphorum

JUNE 24, 2021

That list includes gosuranemab , Roche/AC Immune’s semorinemab which bombed in the phase 2 TAURIEL trial in early-stage Alzheimer’s last year, and TauRx’ tau aggregation inhibitor LMTX which wasn’t able to improve on placebo in a 2016 study. billion.

Immunization 45

Immunization Immunity 45

The Thyroid Pharmacist

JUNE 9, 2023

Food allergies are generated by the IgE branch of the immune system, and reactions will usually show up within minutes of ingesting the reactive food. Food sensitivities, on the other hand, are governed by different branches of the immune system: the IgA, IgM, and IgG branches. 2006;16(3):249-258. doi:10.1089/thy.2006.16.249;

Immunization 98

Immunization Immunity Adverse Reactions 98

The Thyroid Pharmacist

MARCH 24, 2023

While this medication can be helpful for many people and their symptoms, it does not address the underlying root causes of the condition, and may also mask the underlying inflammation that can perpetuate the immune system imbalance and lead to other chronic conditions. 2016 Jul-Aug;38(4):357-60.; J Psychosoc Nurs Ment Health Serv.

Compounding 98

Compounding Immunization Immunity Dosage 98

The Thyroid Pharmacist

OCTOBER 7, 2022

I knew he was right — sugar can contribute to a yeast overgrowth, lowered immunity, blood sugar issues, weight gain, diabetes, and a whole host of health problems (1-3) — but I was a sugar addict, and it was devastating to think that I would have to let go of this old friend and not have any sweetness in my life. doi:10.1155/2016/9132052.

Diabetes 98

Diabetes Immunization Immunity Labelling 98

FDA Law Blog: Biosimilars

NOVEMBER 1, 2023

Even so, the entry of a stay pending final judgment may not be sufficient to immunize parties who rely on LDTs from the PR’s consequences.

Hospitals 81

Hospitals Immunization Immunity 81

PharmaShots

FEBRUARY 13, 2023

In SM, activated mast cells release histamine and other proteins that promote allergic reactions, inflammation, and other immune responses, and people living with the disease. These effects can profoundly impact the quality of life, as patients can. In Europe, there are approximately 40,000 people living with SM.

Chemotherapy 40

Chemotherapy Immunization Immunity Diabetes 40