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Janssen files its first CAR-T therapy cilta-cel in Europe

pharmaphorum

BMS and bluebird had been hoping for a label allowing third-line use. Janssen entered into a worldwide collaboration and license agreement for cilta-cel with the drug’s originator – China’s Legend Biotech – in December 2017.

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Positive safety data for long-term use of MS drug Kesimpta

pharmaphorum

The findings were based on an ALITHIOS Phase 3b open-label extension study of Kesimpta, a targeted B-cell therapy that Novartis says, “delivers superior efficacy with a similar safety and tolerability profile compared with teriflunomide, a first-line treatment for MS.”. years vs initiation two years later. billion in 2019.

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Almirall/Lilly lebrikizumab offers potential long-term management of atopic dermatitis

pharmaphorum

As Dr Thyssen further explained, “[i]t all started with the approval of the first biologic in 2017, and has been followed by the approval of other drugs, including one biologic and [three] oral drugs, in the past [one to two] years.

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Targeting tumours with novel radiopharmaceuticals

European Pharmaceutical Review

Granzyme B is an enzyme released by activated immune cells and using this as a in vivo imaging biomarker has great potential to monitor immune cell activation in a variety of inflammatory diseases, autoimmune diseases, cancer and infections. References Meeting rising demands of a new radiotheranostic era. Internet] Jaafar-Thiel, L.

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Is Stevia Good or Bad for Hashimoto’s Disease?

The Thyroid Pharmacist

I knew he was right — sugar can contribute to a yeast overgrowth, lowered immunity, blood sugar issues, weight gain, diabetes, and a whole host of health problems (1-3) — but I was a sugar addict, and it was devastating to think that I would have to let go of this old friend and not have any sweetness in my life. What About Other Sweeteners?

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Top 9 Takeaways From 2232 People With Hashimoto’s

The Thyroid Pharmacist

Vitamin D supports the immune system by enhancing the pathogen-fighting effects of white blood cells, which are important parts of immune defense. When it leaks into the bloodstream, the body does not recognize it, and labels the structure as a foreign invader and attacks it. It’s also great for boosting our immunity!

Immunity 111
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Hashimoto’s and Graves’ Remission after Helicobacter Pylori Eradication

The Thyroid Pharmacist

8) In very simple terms, this theory hypothesizes that our immune system begins to attack our own thyroid gland because we are infected with a pathogenic organism (like a bacterium, parasite , or virus ), that looks similar to components of the thyroid gland. Molecular mimicry is one of the leading theories of autoimmune disease. (8)