pharmaphorum

FEBRUARY 3, 2022

It said the medical cannabis market in Germany is valued at approximately €122 million, growing at around 25% last year and with a compound annual growth rate estimated at 55 % since the market was liberalised in 2017. The two drugs were developed by medical cannabis pioneer GW Pharma, which was acquired by Jazz last year.

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Compounding 119

pharmaphorum

JANUARY 11, 2023

Anima uses its mRNA Lightning platform to discover small molecules and determine their mechanisms of action for diseases previously deemed undruggable, with scientists searching for compounds that target proteins with roles in regulating mRNA, so as to affect disease states through post-transcriptional regulation (i.e.

Compounding 105

Compounding 105

pharmaphorum

NOVEMBER 3, 2021

The report refers to data collected across 350+ global pharma companies between November 2020 through January 2021, and notes a 70% compound average growth rate in the volume of content managed in Veeva Vault PromoMats since 2018.

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Compounding Communication Pharmaceutical Companies Pharmaceutical Companies 98

European Pharmaceutical Review

NOVEMBER 28, 2024

When the General Data Protection Regulation (GDPR) 1 came into effect in 2018, this appeared to accelerate the migration out of Europe for pharmaceutical clinical trials. This was not so much due to non-compliance but stemmed from regulatory ambiguity.

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Documentation Compounding 105

pharmaphorum

JULY 13, 2022

Bicycle said that none of the compounds in its in-house oncology pipeline, including its immuno-oncology candidates, are included in the Genentech collaboration. Genentech has been looking at the platform since 2020 under the terms of a deal worth up to $1.7

Immunity 105

Immunity Immunization Compounding 105

European Pharmaceutical Review

FEBRUARY 21, 2023

After the substance became legal in the UK in 2018, pharmaceutical companies have faced numerous obstacles to attain a fairer position in the industry. As well as having potential in helping to treat conditions such as chronic pain, developments in the field show the compound could help treat a wider variety of conditions.

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Pharmaceutical Companies Pharmaceutical Companies Compounding Drug Development 132

European Pharmaceutical Review

SEPTEMBER 28, 2022

In 2018, one batch of the generic drug valsartan was recalled due to unacceptable levels of the nitrosamine impurity NDMA. Nitrosamine impurities are undesirable organic compounds with genotoxic, carcinogenic and mutagenic activity. This was the first of numerous recalls due to N -nitrosamine impurities in these types of drug.

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Compounding Pharmaceutical Companies Pharmaceutical Companies 105

Pharmaceutical Business Review

AUGUST 31, 2023

A small molecular compound and a novel type of calcimimetics discovered by Mitsubishi Tanabe Pharma Corporation, Orkedia Tablets suppresses parathyroid hormone (PTH) secretion as it acts on the calcium receptors on parathyroid gland cells.

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Dosage Compounding 52

Quality Matters

AUGUST 22, 2023

Nitrosamines are naturally occurring chemical compounds that people are regularly exposed to at low levels in consumer products and in the environment. In this two-part Quality Matters blog series, we take a look at the FDA’s recent guidance on nitrosamines and what it means for industry.

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Compounding 98

RX Note

MARCH 23, 2023

Today, stability information can be obtained from manufacturer’s labelling information (such as in the package insert), the USP compounding monographs, or peer-reviewed articles and references , such as articles in American Journal of Health-System Pharmacy, the International Journal of Pharmaceutical Compounding.

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Compounding Sterile Compounds Packaging Labelling 52

Pharmaceutical Business Review

OCTOBER 24, 2024

Ketamine has been listed on the drug shortage list of the FDA since February 2018, leading to an increase in the availability of compounded ketamine products not approved by the regulator for psychiatric disorders. Importantly, the FDA has not requested any new preclinical and clinical studies.

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Compounding Hospitals 52

RX Note

JANUARY 21, 2023

Regardless, this post is solely created as a collection of recommended reference.

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Compounding Community Pharmacies Clinical Pharmacology Dosage 40

European Pharmaceutical Review

OCTOBER 19, 2023

The development of novel radiotherapeutics ushered in a new era in targeted treatment 1 for cancer, with two separate radiotherapeutic approvals in Europe and the US, in 2018 and 2022. With alpha particles, you must be very careful how the drug is made to ensure that the compound remains stable between manufacturing and use.

Chemotherapy 105

Chemotherapy Compounding Immunity Immunization 105

pharmaphorum

MAY 26, 2021

Most recently, it partnered with UK startup Inspira on a project to develop an inhaled therapy for COVID-19 based on a plant-derived compound shown to kill the SATS-CoV-2 virus in lab studies, with clinical trials due to start next year. In 2018, there were rumours that the biotech might be acquired by GSK.

Compounding 64

Compounding 64

European Pharmaceutical Review

MAY 3, 2023

A market report has shown that the digital biomanufacturing market is anticipated to grow at a compound annual growth rate (CAGR) of 11 percent between 2023-2035, driven largely by digital transformation. The report also identified that the rising popularity of cloud-based technologies is expected to capture a large portion of the market.

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Compounding 105

pharmaphorum

FEBRUARY 10, 2022

But the goals of maintaining that momentum and reaping the rewards of 21 st century processes rely on the sector attracting and retaining the staff – a proposition that’s becoming increasingly difficult thanks to a stubborn digital skills gap that is being compounded by the COVID brain drain. Digital skills gap. COVID brain drain.

Compounding 105

Compounding 105

The Thyroid Pharmacist

JUNE 30, 2023

Interview With Dr. Mark Mandel To learn more, I decided to interview Dr. Mark Mandel, PharmD, compounding pharmacist, LDN expert, and fellow Midwestern University Chicago College of Pharmacy grad, on the effects of LDN in people with Hashimoto’s and autoimmunity. The transdermal formulation is recommended for children with autism.

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Compounding Immunity Immunization Compounding Pharmacies 98

pharmaphorum

FEBRUARY 2, 2022

The litigation extends back to 2018, when ViiV – a joint venture majority owned by GlaxoSmithKline alongside Pfizer and Shionogi – accused Gilead of infringing its patents on HIV integrase inhibitor dolutegravir. A patent dispute between ViiV Healthcare and Gilead Sciences has been resolved, with Gilead agreeing to pay a $1.25

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Compounding 72

LifeProNow

MARCH 10, 2023

Working alongside a leading university, researchers will also receive access to in-house expertise, compounds, novel tools and technologies and mentoring support to develop their ideas and innovate. This improvement moves AstraZeneca well above the current industry average success rate of 14% in the 2018-2020 timeframe.

Compounding 100

Compounding 100

LifeProNow

MARCH 12, 2023

Working alongside a leading university, researchers will also receive access to in-house expertise, compounds, novel tools and technologies and mentoring support to develop their ideas and innovate. This improvement moves AstraZeneca well above the current industry average success rate of 14% in the 2018-2020 timeframe.

Compounding 100

Compounding 100

RX Note

NOVEMBER 19, 2023

In the rotation, you will be Trained in aseptic techniques to compound sterile preparations inside laminar flow cabinet Trained to ensure the appropriateness of the PN solution supplied in terms of its composition. There is also a chapter of nutritional support in Critical Care Pharmacy Handbook, 2020.

Hospitals 52

Hospitals Documentation Compounding 52

RX Note

MARCH 23, 2023

Introduction Despite the shifting of pharmacy focus to pharmaceutical care, the practice of compounding pharmaceutical formulations remains an essential skill for pharmacists. Ora-Blend Ora-Blend is a flavoured oral suspending vehicle used to simplify the process involved in the extemporaneous compounding of oral suspensions.

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Compounding Health and Personal Care Stores Hospitals Dosage 52

pharmaphorum

FEBRUARY 24, 2021

The main object of the deal is Merck’s MEK 1/2 inhibitor pimasertib, a drug it originally licensed from Santhera Pharmaceuticals more than a decade ago, bringing the drug to phase 2 in melanoma and ovarian cancer and running trials in various other solid tumours and blood cancers before shelving it in 2018.

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Chemotherapy Compounding 83

RX Note

APRIL 8, 2023

ASHP Injectable Drug Information, 2022 Australian Injectable Drug Handbooks, 2020 - free trial is available Davis's Drug Guide for Nurses, 2022 Elsevier's 2023 Intravenous Medications, 2022 External Stability for Parenteral Drugs, 2022 GlobalRPh IV Dilutions Medication Reference and Infusion Guidelines Injectable Drugs Guide, 2011 King Guide Pediatric (..)

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Compounding Hospitals 52

Pharmaceutical Business Review

OCTOBER 9, 2024

The HEAL Initiative is an NIH-wide effort launched in April 2018, aiming to accelerate scientific solutions to the crisis of opioid and stimulant use disorders and pain management. These collaborations have led to the discovery of several novel compounds that are now either in clinical trials or advanced preclinical development stages.

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Compounding Pharmaceutical Companies Pharmaceutical Companies 52

pharmaphorum

JULY 9, 2014

IMS Health forecasts the global market will see a compound average growth rate of between 4 to 7 percent in constant dollar terms to 2018, driven by two very different speed growth engines: at best low single digit value growth in the developed markets, contrasting with largely double digit growth in the power house pharmerging markets.

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Compounding 52

Pharmaceutical Technology

JANUARY 25, 2023

According to the GlobalData deals database, the National Cancer Institute (NCI) in the US has issued 67 grants from 2021-2022 for PROTACs-related studies, while between 2004 and the end of 2018, the NCI issued just 45 grants for PROTACs-related studies.

Compounding 52

Compounding 52

The Happy PharmD

OCTOBER 11, 2024

However, efforts to merge with Walgreens in 2017 and later with Albertsons in 2018 failed, leaving Rite Aid struggling to redefine its place in a competitive market. Compounding its challenges, Rite Aid became entangled in legal issues, notably linked to the opioid crisis.

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Controlled Substances Compounding 52

pharmaphorum

FEBRUARY 22, 2022

It is the first compound to achieve targeted enzyme delivery, using a single domain antibody, directly to blood clots, it says. According to TargED, Microlyse has the potential to offer increased potency and an improved side-effect profile compared to current thrombolytic drugs.

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Compounding 59

Pharma in Brief

MARCH 23, 2021

The patent at issue was Canadian Patent No 2,527,646 (the 646 Patent ), which claims the chemical compound lisdexamfetamine ( LDX ) used to treat attention deficit and hyperactivity disorder ( ADHD ). AU 168 disclosed a class of “advantageous compounds”, one of which was LDX. There was no impermissible redundancy.

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Compounding 52

Pharmaceutical Technology

MAY 12, 2023

GlobalData analyst consensus forecasts project sales to reach $11.5bn by 2029, a 29% compound annual growth rate (CAGR). Eisai signed a licensing agreement with BlissBio in 2018 for the Chinese companies’ exclusive right to use eribulin as their ADC payload. targeting ADC.

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Chemotherapy Compounding 64

Pharmaceutical Technology

NOVEMBER 3, 2022

The funding will be used for the Phase III clinical trial and potential marketing of the investigational compound, ecopipam, for treating Tourette syndrome patients. Emalex was established in 2018 by Paragon Biosciences for developing new central nervous system (CNS) disorder treatments. Tourette syndrome is a serious ailment of CNS.

Drug Development 52

Drug Development Compounding 52

European Pharmaceutical Review

JUNE 29, 2023

This challenge is further compounded by increasingly complex drug formulations and global ingredient supply chains that stretch manufacturers’ capabilities in testing and control of impurities. 1 Nitrosamines are not new or unknown impurities. 1 Nitrosamines are not new or unknown impurities.

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Compounding 98

RX Note

FEBRUARY 8, 2024

Clinical Pharmacy and Therapeutics, 2018 Clinical Pharmacy and Therapeutics is a highly informative reference for any pharmacy student and graduate. Compounding and dispensing competencies. The books are arranged in alphabetical order. Key information in pharmacy is presented in an easy-to-understand format.

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Compounding Hospitals Diabetes 52

European Pharmaceutical Review

SEPTEMBER 25, 2023

NMR relaxation methods distinguish between components (phases or compounds) that have different molecular mobilities For monoclonal antibodies, identification methodologies can employ chromatography, spectroscopy, isoelectric focusing, capillary electrophoresis and peptide mapping techniques. 11 How does NMR relaxometry work? Chromatography.

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Compounding Pharmaceutical Companies Pharmaceutical Companies 98

pharmaphorum

MAY 14, 2021

Biogen meanwhile is also pursuing other avenues of RNA drug discovery and development, and in 2018 expanded the partnership with Ionis Pharma which delivered Spinraza to the market, paying $350 million upfront for a new 10-year alliance.

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Compounding 60

RX Note

JUNE 5, 2023

Workplace activity involves how healthcare workers use and handle the drug in the workplace - such as opening shipments, compounding, administering or cleaning up after use or spills. Oral hazardous drugs No crushing or compounding may be done in an unprotected environment. Consider having spill-response exercises or drills.

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Compounding Packaging Hospitals Chemotherapy 52