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Renal Drug Dosing References

RX Note

Introduction Individualization of a drug dosage regimen for a patient with impaired kidney function is based on the pharmacodynamic/pharmacokinetic characteristics of the drug, the patient's degree of residual renal function, and the patient's overall clinical condition.

Dosage 40
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Indoco receives EIR for its manufacturing facility in Goa (Plant I)

Express Pharma

Indoco Remedies announced the receipt of an Establishment Inspection Report (EIR) with Voluntary Action Indicated (VAI) status from the US Food and Drug Administration (USFDA) for their facility for solid dosages (Plant I) located in Verna, Goa.

Dosage 97
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Effective Drug Patent Prosecution Strategies: Securing Your Pharmaceutical Innovations

Drug Patent Watch

A 2019 survey by the World Intellectual Property Organization (WIPO) found that inadequate prior art searches were responsible for 32% of patent application rejections[2]. A: A composition of matter patent covers the drug compound itself, while a formulation patent covers specific formulations or dosage forms of the drug.

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The F.D.A. Suspends Use of Glaxo Antibody Drug in the U.S.

NY Times

Manufacturers said lab testing revealed that the authorized dosage of the drug was not sufficiently potent against BA.2.

Dosage 98
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ACMT Toxicology Visual Pearl: Who Doesn’t Like a Nice Rosé?

ALiEM - Pharm Pearls

[1,2] Severe symptoms such as hypovolemia, shock, metabolic acidosis Persistent and severe GI symptoms Lethargy or toxic appearance Serum iron level greater than 500 mcg/dL What is the dosage of deferoxamine for iron toxicity? [1] McGraw-Hill Education; 2019 Madiwale T, Liebelt E. 1] Initial dosing starts at 5 mg/kg/hr intravenously.

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Novel anti-epileptic drug demonstrates efficacy

European Pharmaceutical Review

XEN1101 [can] be administered at full strength to begin with” According to Dr French, a key benefit of the drug is its dosage capabilities. It ran between January 2019 and September 2021. The medicine takes over a week to break down in the body. XEN1101 trial findings The Phase IIb study included 285 participants with epilepsy.

Dosage 110
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ACMT Toxicology Visual Pearl: Out of the Blue

ALiEM - Pharm Pearls

What are the indications and dosage for methylene blue? 2019, McGraw-Hill Education: New York. 2019, McGraw-Hill Education: New York. Vitamin C (ascorbic acid) can reduce Fe 3+ , but because it takes 24-48 hours to take effect, it is of limited use in patients with severe methemoglobinemia. PMID 6730477 Howland M. Nelson, et al.,

Dosage 130