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Tranq dope (fentanyl-xylazine combination): A new horizon in opioid withdrawal treatment

ALiEM - Pharm Pearls

Bupe Allergy Buprenorphine induction has been the mainstay of emergency department treatment of opioid use disorder for more than a decade [11, 12]. Of note, screening is often required for insurance approval for substance use treatment. Our experience: Traditionally, ED physicians do not like ordering urine drug screens (UDS).

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Medical Abbreviations

RX Note

. ° Nil © Complete ABG Arterial blood gases abx Antibiotics ACE Angiotensin converting enzyme ACS Acute coronary syndrome ADHD Attention deficit hyperactivity disorder ADME Absorption, distribution, metabolism or excretion ADR Adverse drug reaction AEBA Acute exacerbation of bronchial asthma AF Atrial fibrillation AGE Acute gastroenteritis AIDS Acquired (..)

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Pharma’s post-pandemic launch performance problem: what’s the prognosis?

pharmaphorum

COVID vaccines and treatments have created a substantial market over and above the existing Rx market- IQVIA estimates that the cumulative value of COVID vaccines could be between $185 and 295bn to 2026. On average, launches of 2020’s cohorts both underperformed. The scope of the problem. Launches, therefore, were happening.

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Top 20 RNAi Therapeutic Companies Based on 2022 R&D Expenditure

PharmaShots

This drug is currently in multiple P-IIa clinical trials and is being evaluated in combination with other antiviral agents for cHBV. ARO-AAT and ARO-APOC3 are among the highest-phase products developing under Arrowhead’s pipeline for the treatment of liver diseases. R&D Expenditure: $85.1M R&D Expenditure: $437.9M

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NHC Comments on CMS 2026 Notice of Benefit and Payment Parameters

Putting Patients First Blog

Recognizing PrEP as a preventive service rather than as indicative of an active medical condition, as HHS proposes, could help address the current risk selection seen in the market. Clear guidance on the treatment of rebates within the ACF will help avoid distortions in pricing and prevent patients from bearing disproportionate costs.

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Oral COVID Agents

Pharmacy Friday Pearls

18 years Administration Oral Oral Oral PK/PD MOA: Nirmatrelvir – inhibitor of the SARS-CoV-2 main protease Prevents viral replicationRitonavir is a CYP3A inhibitor included to increase nirmatrelvir plasma levelsRitonavir alone has NO activity against SARS-CoV-2 Time to peak: Nirmatrelvir: 3 hrs & Ritonavir: 3.98 Introduction.

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How Balancing Iron Levels Can Help Your Thyroid

The Thyroid Pharmacist

And as we’ve seen, even with supplementation, you need to address your root causes to prevent iron supply and demand challenges. A 2020 study found that 28 percent of female marathon runners had iron deficiency, compared to only 1.6 Patients on hemodialysis may be prescribed IV or subcutaneous ESAs during dialysis treatments.