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Childhood vaccination coverage was falling across the globe even before Covid

STAT

The study, which estimated childhood vaccination coverage between 1980 and 2023 in 204 countries and territories, found that the Covid-19 pandemic significantly intensified existing immunization challenges. Read the rest…

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STAT+: Cancer therapy’s new ‘gold rush’:  bispecific antibodies that hit key combination of targets

STAT

Immune checkpoint inhibitors, drugs that can help make the immune system recognize and destroy cancer more aggressively, are one of the most important medicines in cancer treatment today. Opdivo, from Bristol Myers Squibb, earned $10 billion in 2023.

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As its cancer vaccine moves through the clinic, Transgene sets sights on manufacturing

PharmaVoice

The company’s myvac platform creates individualized immunotherapies that stimulate and “educate” a patient’s immune system to destroy cancer tumors. We use AI to select the targets most likely to induce a strong immune response and incorporate these neoantigens into our viral vector.”

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Osivax publishes phase 2a results supporting dual flu vaccine approach

Pharma Times

The results, now published in Vaccines , show that the combination was well-tolerated with no serious adverse events, and generated strong immune responses. Robust NP-specific humoral and cell-mediated immune responses were observed in all participants given OVX836, whether alone or with Fluarix Tetra.

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V116 Well-Tolerated With Broad Immune Responses in Pneumococcal Vaccine-Naïve Older Adults

Pharmacy Times

The vaccine showed superior immune response for unique serotypes compared to PPSV23, with higher OPA titers. 1,6,7 Robust Immunogenicity Elicited From V116 Compared With PPSV23 Between January 2023 and May 2023, individuals who were vaccine-naïve were recruited across 8 health care centers in Japan.

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FDA expands AVTOZMA IV approval to include cytokine release syndrome

Pharma Times

CRS is a potentially life-threatening condition triggered by excessive immune activation. Celltrion emphasised the significance of the milestone in advancing treatment options for immune-related conditions. It leads to a rapid release of cytokines into the bloodstream, causing inflammation and damage to healthy tissues.

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SAEM Clinical Images Series: Not Your Average Eczema

ALiEM - Pharm Pearls

He is up to date on childhood immunizations and is not prescribed any oral medications. Copyright Images and cases from the Society of Academic Emergency Medicine (SAEM) Clinical Images Exhibit at the 2023 SAEM Annual Meeting | Copyrighted by SAEM 2023 – all rights reserved. J Emerg Med. 2011 Feb;40(2):167-9. 2007.11.049.