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EU’s Pharma Package falls short of Europe’s goal of global competitiveness

Pharmaceutical Technology

How will RFK Jr’s American dream for vaccines play out? Regardless, EuropaBio’s Olteanu says pharmaceutical and biotech companies in the EU want certainty most of all.

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Big pharma braces for revenue headwinds as patent expiries loom

Pharmaceutical Technology

How will RFK Jr’s American dream for vaccines play out? Other drugs are set to face competition too, with both MSD’s Keytruda (pembrolizumab) and Johnson & Johnson’s (J&J) Darzalex/Faspro (daratumumab and hyaluronidase-fihj) losing US exclusivity by 2029, representing a particular headwind in oncology.

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Organon drug for endometriosis falls short in mid-stage study

BioPharma Dive

The company had hoped to kick off Phase 3 research in 2026 and launch the medicine around 2029. Chief Executive Kevin Ali called the drug a “multibillion dollar opportunity” during the J.P. Morgan Healthcare Conference in January. Organon acquired the drug in its purchase of Forendo Pharma in 2021.

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AbbVie buys $2.1bn Capstan, adding new in vivo CAR-T to pipeline

Pharmaceutical Technology

How will RFK Jr’s American dream for vaccines play out? According to William Blair, forecast revenue rate from 2024 to 2029 growth rate for AbbVie trails only Eli Lilly and Sanofi, representing an “attractive opportunity” for long-term investors.

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Vetter breaks ground on $285m US clinical manufacturing site

Pharmaceutical Technology

How will RFK Jr’s American dream for vaccines play out? The facility will be complete and ready for media fill by late 2029, with plans to move Vetter’s existing clinical operations in Skokie. The planned 160,000ft² facility will focus on aseptic production and includes areas for material preparation and compounding.

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WHO endorses Gilead’s Yeztugo for HIV prevention

Pharmaceutical Technology

How will RFK Jr’s American dream for vaccines play out? The WHO says that the vaccine offers a highly effective, long-acting alternative to daily oral pills and other shorter-acting options. The approval of Yeztugo was hailed as a historical breakthrough by HIV experts and charities.

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Nuvalent Initiates Phase 3 ALKAZAR Trial of Neladalkib in NSCLC

Pharmacy Times

Completion Date (Estimated): December 2029 Neladalkib is a novel brain-penetrant ALK-selective inhibitor that was designed to overcome the limitations observed with currently available ALK inhibitors. 1,2 Currently, neladalkib is also being evaluated in the phase 2 portion of the ALKOVE-1 phase 1/2 clinical trial (NCT05384626).