Remove Chemotherapy Remove Drug Development Remove Vaccines
article thumbnail

STAT+: The long game for weight loss drugs

STAT

Today, we uncover the extent of low-quality generic cancer medicines disseminated globally, see ACIP prepare to raise new questions about vaccines approved long ago, and more. The drug, called pemvidutide, failed to show a statistically significant improvement in liver fibrosis compared to a placebo. 

article thumbnail

Pembrolizumab by Merck for Bile Duct Cancer (Cholangiocarcinoma): Likelihood of Approval

Pharmaceutical Technology

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

Understanding Recent Changes to 505(b)(2) Drugs and Reimbursement

Pharmacy Times

CMS is issuing unique J-codes for 505(b)(2) drugs, classifying them as sole-source products if not therapeutically equivalent. This pathway reduces submission denial risk, accelerates drug development, and offers potential market exclusivity for up to 7 years.

article thumbnail

CAR T and Beyond: The Expanding Pipeline and Promise of Cell Therapies

Pharmacy Times

SHOW MORE With robust pipelines, cell therapy remains the major driver for drug development. The field is expanding into autoimmune diseases, with nononcology trials representing 51% of the pipeline by late 2024. Trends Pharmacol Sci. 2024;45(5):406-418. doi:10.1016/j.tips.2024.03.004

article thumbnail

Beating the Big C

Pharmaceutical Technology

Despite the enormous growth being enjoyed by the global oncology market, potential cancer cures are left on laboratory shelves on a regular basis, according to Dr Victoria John, head of clinical partnerships at Cancer Research UK’s Drug Development Office. “You can get vaccines now to prevent cervical cancer.

article thumbnail

Genomic projects exploit scale as clinical applications play catch-up

Pharmaceutical Technology

Eventually, this understanding can be used for better care, and drug development, as well as for unveiling the role of external factors affecting cancer growth. Space for discovery, development, and repurposing of drugs. The Nature publication touches on this in the case of platinum-based chemotherapy.

article thumbnail

STAT+: Foundation charges cancer patients $83,000 for unproven but promising experimental drug

STAT

Still, when doctors told her last year that the cancer was growing despite two operations, radiation therapy, and a fifth regimen of chemotherapy, the retired business-meeting facilitator decided to do something unorthodox: spend $83,000 out of pocket on an unproven experimental cancer vaccine.

Vaccines 246