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STAT+: Jazz Pharmaceuticals to acquire Chimerix and its experimental brain cancer drug

STAT

It responds poorly to chemotherapy and is usually driven by a mutation that can’t be drugged with traditional approaches. But in a clinical trial presented last year , 14 out of 50 patients with relapsed disease saw their tumors shrink. Median survival is generally cited as less than a year. 

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Opinion: STAT+: Biotech investors: Stop expecting CRISPR science to make big leaps

STAT

An increasing challenge in the treatment of oral cancer is that tumors become resistant to chemotherapy. These studies often do not make a splash in the field and are almost never presented at major meetings, yet they provide guidance as to how best to harness the power of this technology.

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With ADCs on the rise, drugmakers embrace a new oncology pillar

PharmaVoice

And the established target of HER2, present in about one in five instances of breast cancer, helped make Enhertu an important entry, Smith said. At ASCO, one of the most talked-about studies was a late-stage trial in which the treatment outperformed chemotherapy as a first-line drug. Smith called it potentially “practice changing.”

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Insights From ASCO 2025 Guide Pharmacy Practice in Solid Tumors and Hematologic Cancers

Pharmacy Times

Hematologic malignancy presentations brought long-term evidence of benefit with Bruton tyrosine kinase (BTK) inhibitors and BCL2 combinations in chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and promising early-phase results for T-cell engagers (TCEs) in myeloma and lymphoma. months; HR, 0.60; 95% CI, 0.47-0.77);

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New Frontline BTK Inhibitor Strategy Gains FDA Approval in Untreated Mantle Cell Lymphoma

Pharmacy Times

Because of its aggressive nature, MCL is typically treated with combination chemotherapy at diagnosis. Patients often present with peripheral blood, bone marrow, and splenic involvement. For this application, the FDA collaborated with the Australian Therapeutic Goods Administration, Health Canada, and Switzerland’s Swissmedic.

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Study Reveals Gaps in GINA Guideline Adherence for Asthma Treatment

Pharmacy Times

A retrospective study presented at the American Society of Health-System Pharmacists 2025 Pharmacy Futures meeting has revealed significant variability in asthma treatment regimens following initial diagnosis, with many patients not receiving care aligned with the Global Initiative for Asthma (GINA) recommendations. REFERENCES 1.

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Biotech startup Exsure raises Rs 3 Cr in Seed round led by Unicorn India Ventures

Express Pharma

The company aims to reduce the toxic effects of chemotherapy and chances of cancer relapse improving the quality of lives of patients suffering from cancer. The company also plans to present its data for CDSCO approval, strengthen the team size along with expanding its product marketing and sales at a global level.