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It responds poorly to chemotherapy and is usually driven by a mutation that can’t be drugged with traditional approaches. But in a clinical trial presented last year , 14 out of 50 patients with relapsed disease saw their tumors shrink. Median survival is generally cited as less than a year.
An increasing challenge in the treatment of oral cancer is that tumors become resistant to chemotherapy. These studies often do not make a splash in the field and are almost never presented at major meetings, yet they provide guidance as to how best to harness the power of this technology.
And the established target of HER2, present in about one in five instances of breast cancer, helped make Enhertu an important entry, Smith said. At ASCO, one of the most talked-about studies was a late-stage trial in which the treatment outperformed chemotherapy as a first-line drug. Smith called it potentially “practice changing.”
Because of its aggressive nature, MCL is typically treated with combination chemotherapy at diagnosis. Patients often present with peripheral blood, bone marrow, and splenic involvement. For this application, the FDA collaborated with the Australian Therapeutic Goods Administration, Health Canada, and Switzerland’s Swissmedic.
A retrospective study presented at the American Society of Health-System Pharmacists 2025 Pharmacy Futures meeting has revealed significant variability in asthma treatment regimens following initial diagnosis, with many patients not receiving care aligned with the Global Initiative for Asthma (GINA) recommendations. REFERENCES 1.
The company aims to reduce the toxic effects of chemotherapy and chances of cancer relapse improving the quality of lives of patients suffering from cancer. The company also plans to present its data for CDSCO approval, strengthen the team size along with expanding its product marketing and sales at a global level.
SHOW MORE This abstract will be presented at the Oncology Pharmacists Connect (OPC) meeting in Austin, Texas, from June 19 to 20, 2025. Participants can present their work, exchange ideas, and connect with leaders in the field during these networking opportunities. AON Pharmacy's interventions saved $1.9
Pharmacy Times : Can you share what you presented at the 2025 OPC meeting? Blood cancer patients are usually at higher risk due to prior chemotherapy, and maybe we don’t need the same kind of prophylactic medications for solid tumor patients. Pharmacy Times : What challenges currently exist in the treatment of cutaneous malignancies?
Biologics Versus Biosimilars Biologics Image credit: lexiconimages | stock.adobe.com Darkow begins the presentation by describing biologics as a large, complex molecule that is made of living sources, such as bacteria, yeasts, and animal cells. Unlike other medications and treatments, they are not chemically synthesized. REFERENCE Darkow A.
Presented at: Hematology/Oncology Pharmacy Association 2025 Annual Conference; April 9-12, 2025; Portland, OR. If the request doesn’t come in, all 505(b)(2) drugs will be considered nontherapeutically equivalent and therefore get their own J-code. That’s the system we are headed into very rapidly.” REFERENCE Soefje SA.
Benmelstobart (TQB2450; Chia Tai Tianqing Pharmaceutical Group Co, Ltd) in combination with chemotherapy followed by sequential combination with anlotinib (Catequentinib; Advenchen Laboratories) led to significant improvements in progression-free survival (PFS), with a manageable safety profile. months versus 7.79 months with tislelizumab.
Transportation barriers, as a health-related social need, significantly impact FN rates in chemotherapy patients. SHOW MORE This abstract will be presented at the Oncology Pharmacists Connect (OPC) meeting in Austin, Texas, from June 19 to 20, 2025. Febrile neutropenia (FN) remains a serious and common complication of chemotherapy.
Although improved clinical outcomes with the addition of chemotherapy to ICI have been recorded for some patients, there is ongoing research to understand how prognostic factors (eg, smoking history, tumor histology, performance status) can provide some predictive values for patient response to ICI therapy.
SHOW MORE This abstract will be presented at the Oncology Pharmacists Connect (OPC) meeting in Austin, Texas, from June 19 to 20, 2025. Participants can present their work, exchange ideas, and connect with leaders in the field during these networking opportunities.
Pharmacy Times : Can you share what you presented at the 2025 OPC meeting? Kevin Chen, PharmD, MS, BCOP, CPP : Yeah, I presented some therapeutic training updates from ASCO for the treatment of thoracic cancers like lung cancer. Yes, we currently have antibody-drug conjugates that are conjugated to a cytotoxic chemotherapy.
Presented at: American Society of Health-System Pharmacists 2025 Pharmacy Futures. Related Videos Related Content Advertisement June 9th 2025 Neoadjuvant Nivolumab With Chemotherapy Yields Significant Overall Survival Benefit in Resectable NSCLC Luke Halpern, Assistant Editor June 3rd 2025 S2. Ukpokpo EE, Cordon M, Luon S, Renauer M.
SHOW MORE Nivolumab (Opdivo) and chemotherapy demonstrated an overall survival benefit at 5 years, affirming its role as a standard of care option. 1,2 Nivolumab and chemotherapy is a standard of care option for resectable non-small cell lung cancer. months with the combination of nivolumab and chemotherapy, and 24.0%
I recently had the opportunity to blend my own science and philosophy at the Hematology/Oncology Pharmacy Association (HOPA) 2025 Annual Conference in Portland, Oregon, presenting on psychedelic medicines in oncology and palliative care. Fortunately, he had a great oncology team with a pharmacist who specialized in gastrointestinal oncology.
Presented at: American Society of Health-System Pharmacists 2025 Pharmacy Futures. Related Videos Related Content Advertisement June 9th 2025 Neoadjuvant Nivolumab With Chemotherapy Yields Significant Overall Survival Benefit in Resectable NSCLC Luke Halpern, Assistant Editor June 3rd 2025 S2. Updated March 20, 2023. Subscribe Now!
SHOW MORE This abstract will be presented at the Oncology Pharmacists Connect (OPC) meeting in Austin, Texas, from June 19 to 20, 2025. Results and conclusions will be shared during the OPC presentation. Conclusions Conclusions are pending and will be presented at the OPC meeting in Austin, Texas, from June 19 to 20, 2025.
They do present novel therapy options and novel combinations, but that doesn't necessarily mean that they're going to lead to the outcomes we're looking for—longer-term outcomes. Bispecifics are moving up in the lymphoma space, and these newer therapies may have some synergistic effects with chemotherapy. REFERENCES 1.
These findings, which were published in Heart , are intended to enhance the general awareness of cannabis’s potential to cause cardiovascular harm, particularly in those who present or are at risk for serious cardiovascular disorders. Subscribe Now!
Notably, participants given the chemotherapy and EBV-specific cytotoxic T cell (EBV-CTL) therapy achieved better progression free survival and overall survival compared to those who received chemotherapy only. A prior Phase II trial showed benefit of giving T cell therapy following first line chemotherapy.
billion) per year and osteoporotic fractures presently accounting for more than £4.6 Osimertinib (Tagrisso, AstraZeneca ) was accepted, together with chemotherapy, for first-line treatment of adults with advanced non-small cell lung cancer in which the cancer cells have mutations in exon 19 or exon 21 of the EGFR gene. billion (US$6.3
Results and conclusions will be presented at the 2025 Oncology Pharmacists Connect meeting, promoting innovation and collaboration. SHOW MORE This abstract will be presented at the Oncology Pharmacists Connect (OPC) meeting in Austin, Texas, from June 19 to 20, 2025.
Additionally, the VPS72 gene was found to be present in extra copies in over half of the evaluated samples, indicating that gains may play a pivotal role in HCC pathogenesis.
These findings, presented at the 2025 American Society of Clinical Oncology (ASCO) in Chicago, Illinois, aimed to address the unmet need for more effective adjuvant therapies for individuals with completely resected melanoma. Subscribe Now!
A panelist discusses how nonsmall cell lung cancer presents significant treatment challenges due to its prevalence, high mortality rate, poor 5-year survival outcomes, and the difficulty of managing patients with advanced disease who often have poor performance status and multiple metastases, emphasizing the importance of pharmacist involvement for (..)
Results presented from the Phase III IMpower133 study and extension trial IMbrella A, show Roche’s Tecentriq (atezolizumab), in combination with chemotherapy, demonstrates a potential long-term overall survival (OS) benefit as first-line treatment for extensive-stage small cell lung cancer (ES-SCLC). Presented at WCLC 2023.
On Monday, data presented here from a trial of the drug in advanced non-small cell lung cancer provided at least a fuller look. Patients were randomized to either receive chemotherapy or Dato-DXd, which AstraZeneca is developing with Daiichi Sankyo. Continue to STAT+ to read the full story…
MADRID — Results presented Monday could expand the use of a Novartis therapy for metastatic prostate cancer, moving it from a treatment used after chemotherapy to one with demonstrated benefits beforehand as well.
CHICAGO – An experimental drug dramatically slowed the growth of glioma, a type of brain cancer, if the tumor carried a specific type of genetic alteration, researchers said Sunday, potentially sparing patients exposure to radiation and chemotherapy.
WASHINGTON — Congress is considering a must-pass pandemic preparedness bill that presents a good opportunity to fix the nation’s current drug shortages problem, which both parties want to do. But most indications are that lawmakers will let that opportunity pass them by.
When it hit the market in 2013, the drug revolutionized the treatment of these cancers and represented a major step forward from chemotherapy and some other drugs at the time. NEW ORLEANS – One of the best therapies for some types of lymphoma and leukemia has been a drug called ibrutinib, made by AbbVie.
So join us as we hoist the ever-present cup of stimulation — our choice today is gingerbread — and attack the fast-growing to-do list. Cisplatin is a type of chemotherapy drug used alone or in combination with other drugs to treat several advanced forms of cancer, including bladder, ovarian and testicular cancer.
The PHERGain II study’s goal is to find an effective therapeutic strategy that can reduce the use of chemotherapy and improve the quality of life of patients without compromising the clinical effectiveness of their treatment.
So join us as we hoist the ever-present cup of stimulation — our choice today is coconut rum — and attack the fast-growing to-do list. The medicine, Dato-DXd, is a type of next-generation chemotherapy called an antibody-drug conjugate that AstraZeneca and other companies are investing in heavily.
Data from the second interim analysis of the DETECT V trial, presented at ESMO Congress 2024, suggest that a chemotherapy-free regimen combining dual HER2-targeted therapy with endocrine therapy, particularly with the addition of ribociclib, may be an effective treatment for patients.
Epicur Pharma’s Advisory Council member Ann Donoghue, DVM, MS shares her personal perspective on the important relationship between veterinary oncology and compounded medications used in chemotherapy treatments. Many of the presentations discussed the chemotherapies available to treat dogs.
Published date: 17/04/2023 Summary: Cantargia (Cantargia AB; Nasdaq Stockholm: CANTA) today presented updated interim clinical efficacy data including subgroup analyses of first-line pancreatic cancer (PDAC) patients treated with the antibody nadunolimab (CAN04) and chemotherapy in the phase I/IIa CANFOUR trial. months; p=0.017).
pharmaphorum sat down with Sunil Verma, global head of oncology, medical, at AstraZeneca, to discuss three studies that were presented at the show, which demonstrate a few of the ways oncology is advancing through precision medicine and targeted therapies. And once it’s present there, it’s taken up by the cancer cell.
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