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Third Circuit Affirms Rejection of AstraZeneca’s Challenges to IRA Drug Price Negotiation Program

Big Molecule Watch

On May 8, 2025, the Court of Appeals for the Third Circuit affirmed the district courts dismissal of AstraZenecas challenges to the Inflation Reduction Acts Drug Price Negotiation Program and CMSs Guidance implementing the Program. Farxiga (dapagliflozin) is used to treat diabetes, heart disease, and kidney disease.

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Understanding Recent Changes to 505(b)(2) Drugs and Reimbursement

Pharmacy Times

This pathway’s expanded use and shifting Centers for Medicare & Medicaid Services (CMS) policies are reshaping reimbursement practices and therapeutic equivalence standards for 505(b)(2) drugs.

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The GLP-1 Gold Rush: Why Compounded Alternatives Are a Risky Bet

Pharmaceutical Commerce

The allure of compounded alternatives: A closer look at the "gold rush" The intense demand for GLP-1 agonists stems from their proven efficacy in managing type 2 diabetes and, increasingly, in facilitating significant weight loss. How Recent Executive Orders Impact the Drug Pricing Landscape. References 1. Health Prem.

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STAT+: Pharmalittle: Pfizer and Novo disclose upbeat data on oral weight loss drugs; PBM trade group blasts House committee over hearing

STAT

A lower-dose version of the drug is already approved as a treatment for type 2 diabetes under the brand name Rybelsus. Meanwhile, an oral drug from Pfizer causes a similar amount of weight loss as Ozempic, according to results from a Phase 2 clinical trial, CNBC says. Walgreens asked a U.S. Walgreens asked a U.S.

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The Prescription-Discount Advantage For Self-Insured Companies. And Their Employees.

Proxsys Rx

The skyrocketing costs of prescription drugs It’s no secret that prescription drug prices are rising faster than the rate of inflation, forcing employers to shift more of their prescription benefit costs to their employees and families. This usually means higher deductibles, higher co-pays, and lower morale among employees.

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ProxsysRx’s MedServRx: The Prescription-Drug Advantage For Patients And Their Providers

Proxsys Rx

The growing problem of prescription non-adherence According to a study published in the Annals of Internal Medicine, nearly 1/3 of all prescriptions are never filled by patients, and up to half of medications for chronic conditions like diabetes and hypertension are never taken.