Fri.May 09, 2025

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Coliform bacteria and E. coli in pharma water systems: A hidden threat to product integrity

Express Pharma

The COVID-19 pandemic brought microbiology to the public eye, making terms like RT-PCR, antigen, and PPE kit part of everyday discussions. In the pharmaceutical world, another set of terms-coliforms and E. coli-carry immense importance, especially where water quality is concerned. Water is a critical utility in pharma manufacturing processes and is used in various stages, including formulation, cleaning, and even as raw material in some products.

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Secrets of Pharmaceutical Market Access

Pharma Marketing Network

What does it take to bring a life-saving therapy to market and ensure patients can actually access it? Behind every successful drug launch lies a labyrinth of negotiations, pricing models, and payer strategies. Understanding the pharmaceutical market access process is crucialnot only for commercialization teams but for marketers and strategists looking to position their brands competitively.

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Innovative CAR T therapy could deliver in broader therapeutic settings, research suggests

European Pharmaceutical Review

A next-generation CAR T cell therapy has shown promise for treatment-resistant B-cell lymphoma, new research shows. Results from the Phase I clinical trial found that the treatment reduced cancer in 81 percent of patients, and enabled complete remission in 52 percent of patients. These findings are notable, because over half of lymphoma patients given currently available CAR T therapies, a form of personalised immunotherapy, do not experience long-term remission, the researchers explained.

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EU Approves AstraZeneca Mantle Cell Lymphoma Treatment

PharmaTech

Calquence (acalabrutinib) plus bendamustine and rituximab reduced risk for disease progression or death by 27% compared with the current standard of care, according to a phase III trial.

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Vor Bio winding down as multiple biotechs downsize

pharmaphorum

Biotech pressures exposed as big job losses are announced at Vor Bio, IGM Biosciences, Rallybio, Insitro, and Korro Bio.

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GLP-1 Drug Repurposing for Addiction Disorders Hampered by High Costs and Legal Hurdles

PharmExec

Armando Castro, partner, emerging companies, venture capital, Lowenstein Sandler, explains how regulatory, patent, and reimbursement challenges are slowing venture investment in GLP-1 and psychedelic addiction therapies.

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Is the Industry Ready for the DSCSA?

Pharmaceutical Commerce

In the second part of his Pharma Commerce video interview, Michael Rowe, Two Labs senior director of DSCSA/serialization compliance services, comments on stakeholders overall preparedness for complying with the latest enforcement deadlines.

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AZ plots wider Imfinzi use in bladder cancer after trial win

pharmaphorum

AstraZeneca's run of positive trial results with its cancer therapies has continued with a win for its immunotherapy Imfinzi in early bladder cancer

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Gilead’s Livdelzi Shows Lasting Efficacy in Primary Biliary Cholangitis, Regardless of Prior Therapy

PharmExec

Interim results from the ongoing Phase III ASSURE trial demonstrated that Livdelzi maintained a consistent biochemical response in patients with primary biliary cholangitis.

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Pharma still in waiting mode after UK-US trade agreement

pharmaphorum

Hopes that the UK-US trade agreement would give some clarity on the situation for pharmaceuticals proved optimistic.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Breaking New Ground: Emerging Therapies for Treatment of EGFR-Positive NSCLC

Pharmacy Times

A panelist discusses how emerging advancements in nonsmall cell lung cancer (NSCLC) treatment include the anticipated FDA approval of subcutaneous amivantamab, which would significantly reduce infusion-related reactions seen in the MARIPOSA trials while improving patient experience and reducing infusion center chair time, as well as promising antibody-drug conjugates like sacituzumab govitecan (Trodelvy) that may provide better first and second-line treatment options with potentially less toxici

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The value of a partner, globally and locally

pharmaphorum

With the FDA and EMA releasing their annual reports detailing novel drug approvals in 2024, a new pharmaphorum podcast looks at recent trends related to drug approvals, as well as challenges and opportunities both small and large pharma companies face in the year ahead.

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Opinion: Requiring a four-year emergency medicine residency is a terrible idea

STAT

Less than two years ago, I completed a three-year emergency medicine residency and, after passing written and oral board exams, became a board-certified emergency physician. Now, the Accreditation Council for Graduate Medical Education is claiming that three years of personal and financial sacrifice are not enough.  The ACGME reviews each specialty’s program requirements every 10 years, and it recently released their proposed updates for emergency medicine.

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HLS Therapeutics and Esperion partner to commercialise oral cardiovascular medicines

Pharmaceutical Technology

HLS Therapeutics has signed an agreement with Esperion Therapeutics for commercialising Nexletol and Nexlizet in Canada.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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14 Ways Birth Control Pills Rob Us of Our Health

The Thyroid Pharmacist

At the time I was first diagnosed with Hashimotos, I knew that I was not yet ready to start a family. With my health being less than optimal, it was obvious to me that an unplanned pregnancy would wreak havoc on my health, and that I would need to postpone any plans to have children. At the same time, I was a pharmacist and knew through both training and my first-hand experience, that taking artificial hormones in the form of birth control pills was contributing to my poor health.

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Health Economics and Outcomes Research (HEOR) in Pharma

Viseven

When faced with life-or-death treatment decisions, healthcare stakeholders need more than clinical data alone they need a complete picture of both effectiveness and value. Health Economics and Outcomes Research (HEOR) delivers this by uncovering the true impact of therapies on patient outcomes , healthcare costs, and quality of life. For the pharmaceutical industry, HEOR isnt just an analytical tool, its a strategic necessity, shaping decisions that determine market access, pricing, and long-te

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Estrogen Dominance as a Trigger for Hashimoto’s

The Thyroid Pharmacist

Over the years of working with people with Hashimotos, it has become clear to me that there is a strong relationship between sex hormones and thyroid hormones. One clients story comes to mind as one that will resonate with many of you. At the time, this client had just turned 40 and started to see some changes in her previously very regular cycle, including mid-cycle spotting and a heavier flow.

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Giving weight loss jabs could bolster UK economy by £4.5bn a year, study says

The Guardian - Pharmaceutical Industry

Providing semaglutide for all those eligible may bring productivity gains as people are able to work more Giving weight loss jabs to everyone eligible for them could boost the UK economy by 4.5bn, according to research. Worldwide, about 3.8 billion people over 25 and just under 750 million children and young people are forecast to be overweight or obese by 2050.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Pharma Pulse 5/9/2025: Teva Plots Thousands of Job Cuts as Restructuring Drive Enters 'Acceleration' Phase, Takeda to Invest $30B Into US Operations

Pharmaceutical Commerce

Business strategies and top news in the biotech / biopharma industry, including market access, supply chain distribution and more.

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FDA chief Martin Makary sets June deadline for genAI rollout

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has set an "aggressive" timeline to implement genAI across the agency by 30 June 2025.

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Live Zoster Vaccine May Reduce Risk of Cardiovascular Events by 23%, Study Finds

Pharmacy Times

The most substantial reduction was achieved 2 to 3 years after vaccination with a sustained protective effect lasting up to 8 years

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First at-home test kit for cervical cancer approved by the FDA, company says

STAT

WASHINGTON — U.S. regulators have approved the first  cervical cancer  testing kit that allows women to collect their own sample at home before shipping it to a laboratory, according to a medical device company. Teal Health said Friday the Food and Drug Administration approved its Teal Wand for home use, offering a new way to collect vaginal samples that can detect the HPV virus that causes cervical cancer.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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AUC 5 vs AUC 6: MUSC Study Highlights the Tradeoffs in Neoadjuvant Breast Cancer Treatment

Pharmacy Times

Lacy La Fever, PharmD, MS, discussed outcomes associated with different carboplatin AUC dosing strategies.

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Galimedix completes key stage of clinical trial for treatment targeting eye and brain diseases

Pharmafile

Clinical biotech, Galimedix Therapeutics, has announced the completion of a single ascending dose (SAD) part of a phase 1 study of GAL-101, a novel therapy aimed to treat serious neurodegenerative eye and brain conditions. The SAD study showed that GAL-101 was well-tolerated and has a strong safety and pharmacokinetic profile. These promising results have allowed […] The post Galimedix completes key stage of clinical trial for treatment targeting eye and brain diseases appeared first on Ph

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Study Finds Endometriosis May Be Linked to Traumatic Experiences

Pharmacy Times

These findings demonstrate an association that is independent of the diseases genetic predisposition.

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Healthcare Advertising That Works: Data-Driven Pharma Campaigns That Convert

Pharma Marketing Network

Is your healthcare advertising generating the conversions your pharma brand needs? In todays competitive, digitally saturated market, traditional messaging no longer cuts it. Precision targeting, performance insights, and adaptive content are essential to reach both healthcare professionals (HCPs) and patients effectively. Fortunately, the rise of data-driven strategies is helping marketers build more intelligent campaigns that truly convert.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Considerations for the Use of Abemaciclib vs Ribociclib in Breast Cancer

Pharmacy Times

Abemaciclib and ribociclib have various risks and benefits in treating early breast cancer, highlighting the importance of patient-provider communication.

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FDA Grants Accelerated Approval to Verastem Oncology’s Avmapki Fakzynja Co-Pack for KRAS-Mutated Recurrent Low-Grade Serous Ovarian Cancer

PharmExec

The Avmapki Fakzynja Co-Pack marks the first FDA-approved treatment for adult patients with KRAS-mutated recurrent low-grade serous ovarian cancer who have received prior systemic therapy.

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Plozasiran Shows Promise as Cholesterol-Lowering Treatment for Mixed Hyperlipidemia

Pharmacy Times

Plozasiran shows promise in reducing cholesterol and triglyceride levels in patients with mixed hyperlipidemia and other harmful conditions, addressing significant cardiovascular risks.

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RFK Jr.’s autism fixation hearkens back to his stance on vaccines

PharmaVoice

The head of HHS is seeking the “root causes” of autism spectrum disorder through a large government research project.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.