January, 2024

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PharmaVoice’s Crystal Ball: What’s next in drug innovation and clinical trials

PharmaVoice

As advanced therapies and patient perspectives strengthen their foothold in R&D, pharma is poised to deliver impactful treatments in record time.

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Pharmacy First: Are the floodgates about to open?

The Pharmacist

EXCLUSIVE: With the launch of Pharmacy First in England just days away, an under-pressure community pharmacy sector is torn between welcoming the opportunity and wondering whether patient demand will exceed its capacity. From 31 January, the launch of the highly anticipated service will see patients able to access advice and treatment for seven common conditions […] The post Pharmacy First: Are the floodgates about to open?

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Pharma Horizons: Artificial Intelligence

European Pharmaceutical Review

The first in our inaugural Pharma Horizons report series is dedicated to exploring the latest advances in artificial intelligence (AI) and machine learning (ML) for drug development, pharmaceutical manufacturing and quality control. AI/ML is predicted to be the top technology investment for 60 percent of life sciences companies over the next two years, according to a recent survey 1 from the Pistoia Alliance.

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Some dementia patients might have reversible symptoms caused by cirrhosis, study says

STAT

The descent into dementia can feel like traversing a minefield, coming across new symptoms without the hope of a cure. But some dementia patients, even up to 10% of people diagnosed with the condition, might actually have undiagnosed liver disease and accompanying neurological problems, a new study in JAMA Open Network suggests. Most importantly, it’s possible their liver-related brain symptoms could be resolved with treatment.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Prescribing Success: Dr. Linda Gutierrez-Miller’s Journey to Impactful Clinical Pharmacy and Inspiring Resilience!

Pharmacy Is Right For Me

“How can I make the biggest difference in the lives of others? How can I help the most people?” These questions often cross the minds of students as they navigate the labyrinth of career choices. Dr. Linda Gutierrez-Miller, one such student, embarked on a journey to answer these questions, ultimately choosing a career path that aligns with her goals of making a substantial impact and aiding a diverse range of individuals—clinical pharmacy.

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CAR-T for lupus: the ‘tip of the iceberg’ for cell therapy in autoimmune disease

BioPharma Dive

Since a landmark paper in 2022, drugmakers have begun nearly a dozen trials of cell therapies for lupus, with more set to start. Here’s why their efforts are worth watching.

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More Trending

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‘Medicine is going personalised’: Moderna’s UK boss on the coming vaccine revolution

The Guardian - Pharmaceutical Industry

Darius Hughes was a key figure in Pfizer’s pioneering Covid vaccine drive. Now he has changed companies – and sees a big future for mRNA technology The man who launched Pfizer’s Covid-19 vaccine in the UK three years ago – when 90-year-old Margaret Keenan in Coventry became the first person in the world to receive one – is now overseeing the construction of a manufacturing and research centre in Oxfordshire for rival US jab maker Moderna.

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JPM: Four ways FDA is seeking to buoy gene therapy

pharmaphorum

Dr Peter Marks, director of the FDA Center for Biologics Evaluation and Research told a packed house in San Francisco for JPM that FDA wants to support gene therapies in 2024.

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Scientists document first-ever transmitted Alzheimer’s cases, tied to no-longer-used medical procedure

STAT

LONDON — There was something odd about these Alzheimer’s cases. Part of it was the patients’ presentations: Some didn’t have the classic symptoms of the condition. But it was also that the patients were in their 40s and 50s, even their 30s, far younger than people who normally develop the disease. They didn’t even have the known genetic mutations that can set people on the course for such early-onset Alzheimer’s.

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Infant formula recalled over contamination fears

The Pharmacist

Two Reckitt infant formulas have been recalled over concerns that they are contaminated with the bacteria Cronobacter sakazakii. Batch ZL3F7D of Nutramigen LGG Stage 1 Hypoallergenic Formula 400g and batches ZL3FAA and ZL3FDM of Nutramigen LGG Stage 2 Hypoallergenic Formula 400g may have been contaminated with the bacteria, the Food Services Authority (FSA) has said. […] The post Infant formula recalled over contamination fears appeared first on The Pharmacist.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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10 clinical trials to watch in the first half of 2024

BioPharma Dive

A non-addictive pain pill faces its definitive test, while study results in ALS, a rare heart disease and lung cancer could have far-reaching implications.

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Merck is on the lookout for more opportunities within immunology

Pharmaceutical Technology

At the JP Morgan Healthcare conference, Merck (MSD) indicated its eagerness to continue to establish its place in the immunological space.

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PulmCrit hot take: VAP prophylaxis (PROPHY-VAP trial)

EMCrit Project

background: ANTHARTIC trial Prophylaxis against VAP (ventilator associated pneumonia) has is already supported by a few studies in the literature, perhaps most notably the ANTHARTIC trial. That was a multi-center RCT evaluating 48 hours of therapy with ampicillin-sulbactam for patients intubated following cardiac arrest. Antibiotic therapy reduced early-onset VAP, with a trend towards more ventilator-free […] EMCrit Project by Josh Farkas.

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Why amplifying the patient voice is crucial to clinical trial success

pharmaphorum

Amplifying the patient voice is essential for the success of clinical trials. Learn why it is crucial for patient engagement, recruitment, and overall trial success, and how it can address challenges such as transportation and financial barriers.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Opinion: I’m an anesthesiologist. Kenneth Smith’s execution by nitrogen gas was far from ‘textbook’

STAT

On Thursday evening, the state of Alabama executed Kenneth Eugene Smith by nitrogen gas. Now, there are dueling narratives about what happened. Alabama claims it went perfectly, proving that nitrogen is a humane, effective alternative to lethal injection (which it previously tried, unsuccessfully, to use on Smith). It says that based on this experience, other states should follow its example.

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How Quantum Computing Will Impact Pharma in 2024: Q&A With Erik Huestis, Partner at Foley Hoag

PharmExec

Huestis discusses the ways that quantum simulation and quantum systems can be used in areas such as drug discovery and the creation and protection of intellectual property in the life sciences industry.

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A new startup from Feng Zhang and an ex-Illumina executive zeroes in on the epigenome

BioPharma Dive

Moonwalk Biosciences, the latest biotech cofounded by the gene editing scientist, joins other startups aiming to alter gene expression without changing DNA.

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Wear PPE for suspected measles, pharmacies told

The Pharmacist

Community pharmacies are among the 'most likely' places to encounter a case of measles, NHS England (NHSE) has warned. And staff have been instructed to 'take appropriate action' and wear personal protective equipment (PPE) to 'stop onward transmission without delay', when dealing with patients with suspected measles. This comes as the UK Health Security Agency […] The post Wear PPE for suspected measles, pharmacies told appeared first on The Pharmacist.

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PulmCrit – Validation of my model for converting VBGs to ABGs

EMCrit Project

background and general concept My research project in fellowship was the construction of a mathematical model to convert VBG values into ABG values. The fundamental concept for the model was pretty simple: we can approximate the respiratory quotient (RQ) of tissue in the hand as being constant. This indicates that changes in oxygen content and […] EMCrit Project by Josh Farkas.

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Data-driven disease research harnessing the genome

pharmaphorum

Discover how the UK Biobank is leveraging technology and the power of genomics in data-driven disease research. Join the digital revolution in understanding and combating diseases using cutting-edge techniques and large-scale genomic data analysis.

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HPV vaccine study finds zero cases of cervical cancer among women vaccinated before age 14

STAT

A historic new study out of Scotland shows the real-world impact of vaccines against the human papillomavirus: The country has detected no cases of cervical cancer in women born between 1988-1996 who were fully vaccinated against HPV between the ages of 12 and 13. Many previous studies have shown that HPV vaccines are extremely effective in preventing cervical cancer.

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Transforming pharmaceutical manufacturing: The AI revolution

European Pharmaceutical Review

Revolutionising quality control In the backdrop of stringent quality standards and regulatory demands inherent to pharmaceutical manufacturing, the addition of AI technologies introduce a paradigm shift. This article highlights the manifold applications of AI, particularly cutting-edge image recognition and computer vision systems, which profoundly impact quality control.

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Kyverna sets plans for IPO in test of biotech market

BioPharma Dive

The offering is the fifth outlined by a biotech startup this month, suggesting companies are becoming more willing to gauge investors’ appetite for new stock offerings.

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AbbVie and Umoja to develop new CAR-T therapies for cancer

Pharmaceutical Technology

AbbVie and Umoja Biopharma partnered for the development of in-situ CAR-T cell therapy candidates for oncology targets.

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EMCrit 366 – Should Delayed Sequence Intubation (DSI) become the Standard for Critical Care Intubations?

EMCrit Project

Should DSI become the new standard? EMCrit Project by Scott Weingart, MD FCCM.

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Novavax: Creating tomorrow’s vaccines today

pharmaphorum

Novavax is a leading pharmaceutical company dedicated to creating protein-based vaccines for diseases like COVID-19 and malaria. Learn more about their innovative vaccine development process and their commitment to creating a healthier future.

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New chronic Covid study offers insight into which immunocompromised patients are most at risk

STAT

You’ve heard of long Covid, a condition in which the acute infection subsides but troubling symptoms persist. Less well known is chronic Covid: The virus just doesn’t leave, sometimes staying in patients’ bodies long enough to mutate into new variants. This happens to people whose immune systems are compromised, whether through disease or treatment, leaving them vulnerable to infections that last weeks, months, or, in one known case, a year.

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Statins Could Potentially Slow Deterioration of Cognitive Function for Those With Alzheimer Disease

Pharmacy Times

Due to the observational nature of the study, the study authors said they cannot determine causal relationships between statins and cognitive decline for patients with Alzheimer disease.

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AstraZeneca, Daiichi aim for first pan-tumor ADC approval

BioPharma Dive

The FDA is reviewing the companies’ application for a “tumor agnostic” indication for their drug Enhertu, which would break new ground for antibody-drug conjugates.

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Why many more people are lining up for a flu shot than a Covid vaccine

STAT

America is over the Covid vaccine. Frantic lineups for scarce doses when Covid vaccines first became available have long since given way to widespread indifference. Each new round of boosters has drawn fewer bared arms than the round before it. The Centers for Disease Control and Prevention estimates that, as of Jan. 6, a mere 21.5% of Americans aged 18 and older and 11% of children have been vaccinated with the latest Covid vaccine.

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Rollout of a new malaria vaccine kicks off in Africa

STAT

LONDON — Starting Monday, a new, highly effective malaria vaccine will be rolled out for the first time, as an immunization campaign for children kicks off in Cameroon — a day that global health officials say marked a historic step in the decades-long quest to protect people from one of the world’s deadliest infections. The vaccine drive in Cameroon — the first launch of the vaccine outside of clinical trials and pilot programs — comes as some 20 African countr

Vaccines 363
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Merck CEO refused to testify in Senate because he’s not an expert in drug pricing, Bernie Sanders says

STAT

WASHINGTON — Sen. Bernie Sanders on Thursday jabbed the CEO of Merck for telling congressional staff that he didn’t have the expertise to testify at a Senate hearing on prescription drug prices because he’s a tax attorney. Sanders, who has threatened to subpoena the CEOs of Merck and Johnson & Johnson over their refusal to testify at a hearing on why drug prices are higher in the United States than other countries, told reporters the reasons the companies gave ranged fro

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STAT+: Judge skeptical of arguments against Medicare drug price negotiation

STAT

WILMINGTON, Del. — Wednesday was the first time that a federal judge asked questions in-person of drug industry lawyers who are trying to stop Medicare from negotiating drug prices. It didn’t go well for them. AstraZeneca’s lawyers argued that Medicare’s new powers amount to a taking of their property rights without due process.

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STAT+: Ultima Genomics launching high-end DNA sequencers that can read genome for $100

STAT

Ultima Genomics, an upstart some observers have called a “ dark horse ” in the world of DNA sequencing, will soon launch a line of high-power instruments that can read a human genome for as little as $100, the company’s leadership told STAT. The sequencer, dubbed the UG 100, is a $1.5 million machine that can read up to 20,000 human genomes a year.

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