October, 2022

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Boston University researchers’ testing of lab-made version of Covid virus draws government scrutiny

STAT

Research at Boston University that involved testing a lab-made hybrid version of the SARS-CoV-2 virus is garnering heated headlines alleging the scientists involved could have unleashed a new pathogen. There is no evidence the work, performed under biosecurity level 3 precautions in BU’s National Emerging Infectious Diseases Laboratories, was conducted improperly or unsafely.

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5 impactful drug trial failures from the last year

PharmaVoice

Major recent trial flops and what they mean for companies, patients and the industry.

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Eli Lilly receives marketing authorisation for baricitinib

Pharma Times

Treatment involves adult patients with severe alopecia areata

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Thérèse Coffey criticised for giving leftover antibiotics to a friend

The Guardian - Pharmaceutical Industry

Health secretary accused of ‘monumental stupidity’ for saying she had shared a prescribed medication Doctors have rounded on the health secretary, Thérèse Coffey, after she admitted to sharing prescription medicines with others, actions the British Medical Association described as both dangerous and against the law. Coffey told civil servants in a meeting last month that she had given leftover antibiotics to a poorly friend, an admission that came as the discussion on how to alleviate pressures

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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EMCrit 335 – APRV TCAV for Lung Rescue Made Simple with Rory Spiegel

EMCrit Project

Every Resus doc should be able to crash a patient on to APRV for lung rescue. EMCrit Project by Scott Weingart, MD FCCM.

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Growth in Cell and Gene Therapy Market

PharmaTech

Biopharma focuses on streamlining biomanufacturing and supply chain issues to drive uptake of cell and gene therapies.

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Tips for tackling trial recruitment and retention woes in oncology

PharmaVoice

How new tools are helping companies find and keep cancer patients in clinical studies.

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Parliament square set for ME research demonstration

Pharma Times

Demonstrators will demand hundreds of millions of pounds ‘missing’ from ME research

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Tackling immune-mediated disease with CAR Tregs

European Pharmaceutical Review

In recent years there has been significant development within the cell therapy field, as chimeric antigen receptor (CAR) T-cell therapy demonstrated an ability to transform the treatment of patients with haematological malignancies. Recognising the potential of CAR T cells to act as highly targeted therapeutics, several biotechnology companies – including Sangamo Therapeutics – have established development pipelines of CAR T regulatory cells (Tregs) that aim to tackle immune?

Immunity 140
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Verge Genomics takes AI-sourced drug for ALS into clinic

pharmaphorum

Verge Genomics has joined a select group of biotechs who have taken a drug discovered and developed using artificial intelligence into human testing. The small-molecule PIKfyve inhibitor – called VRG50635 – has been administered to the first subject in the phase 1 trial involving healthy volunteers, according to the San Francisco-based biotech, which was founded in 2015 by Alice Zhang and Jason Chen.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Could SIBO Be Preventing Your Remission from Hashimoto’s?

The Thyroid Pharmacist

Many people with Hashimoto’s feel significantly better when they remove reactive foods, replenish nutrient depletions with restorative foods and supplements, and support the gut with probiotics. But what if those steps alone don’t work? You’ll have to dig a bit deeper. It took more than the implementation of the strategies above for me to resolve all my symptoms related to Hashimoto’s.

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Human neurons implanted in a rodent’s brain lead a rat to water — and make it drink

STAT

The scientist flicked on a laser, filling the rat’s brain with blue light. The rodent, true to its past two weeks of training, scampered across its glass box to a tiny spout, where it was duly rewarded with a drink of water. From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

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The digital therapeutics revolution is happening and Big Pharma is buying in — with caution

PharmaVoice

Companies like Pfizer, Novartis, Sanofi and BMS are diving into the world of digital therapeutics while recognizing the limitations of the young field.

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‘Junk’ DNA may hold the key to neurological disorders

Pharma Times

University of Lincoln and the University of Sheffield are researching how DNA could be repaired

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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Robotic capsule could replace injected biologics

European Pharmaceutical Review

Scientists at MIT have demonstrated that a novel robotic capsule could potentially replace conventional biologic injection methods by tunnelling through the intestinal mucus barrier to deliver insulin. The research, published in the journal Science Robotics described how the new drug delivery system can transport large protein and small-molecule drugs, like vancomycin, an antibiotic peptide.

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PDUFA and BsUFA reauthorizations are wins for patients

PhRMA

America relies on the U.S. Food & Drug Administration (FDA) to keep pace with the scientific advancements happening every day in labs across the country. That’s why the recently enacted Prescription Drug User Fee Act (PDUFA VII) and Biosimilar User Fee Act (BsUFA III) are both great news for biopharmaceutical innovation and for patients. With these programs reauthorized for another five years, the FDA can continue doing its vital work reviewing medicines.

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2022 CVS Health Minority Scholarship For Pharmacy Students Winners Announced

Pharmacy Is Right For Me

We’re thrilled to announce the winners of the 2022 CVS Health Minority Scholarship for Pharmacy Students! The CVS Health Minority Scholarship for Pharmacy Students is a scholarship program launched in 2019 thanks to the generosity of CVS Health in partnership with the American Association of Colleges of Pharmacy (AACP). About this scholarship program The scholarship program is designed to support and promote a diverse population of student pharmacists by reducing financial barriers for underrepr

Immunity 130
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Nobel Prize in medicine awarded for research into the evolutionary history of humankind

STAT

A Swedish scientist won the 2022 Nobel Prize in medicine or physiology on Monday for his groundbreaking research into the evolutionary history of humankind. Svante Pääbo, of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, accomplished something widely believed to be impossible: recovering and reading DNA from 40,000-year-old bones.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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What’s keeping pharma leaders up at night

PharmaVoice

C-suite execs in the life sciences share their late-night thoughts including innovation, patient access and market factors.

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UK lags behind other nations in research and development

Pharma Times

UK only places 11th in terms of total R&D investment as a percentage of GDP

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Clinical success begins early for small molecule drugs

European Pharmaceutical Review

The race to the first-in-human (FIH) milestone is underscored by the rise in expedited programmes such as Fast Track designation, Accelerated Approval, Priority Review designation and Breakthrough Therapy designation. 1 Within these programmes, the ability to identify and solve challenges in the early stages with agility and flexibility is critical to successful early clinical trials that will help advance drugs from late stage through product launch.

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Mental Illness Awareness Week – A time for reflection

PhRMA

Each first week of October, Americans all across the country take time to reflect on an issue which is increasingly recognized as impacting everyone, whether it be directly as it does me, or indirectly through a family member or friend: mental illness. Mental Illness Awareness Week is an opportunity to raise awareness about the impacts of mental illness and to better understand and educate communities about what it means to face a mental illness, deal with significant moments of stress throughou

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Janssen leads effort to cut waste in digital health devices

pharmaphorum

A consortium of industry and academic groups – led by Johnson & Johnson’s pharma division Janssen – has been set up to tackle the environmental impact of digital health products, specifically aimed at minimising waste that could end up in landfill. The Digital Health in a Circular Economy (DiCE) group was formed earlier this year with the aim of developing ways to “design, collect, directly reuse, refurbish, remanufacture, and recycle digital health devices.” The programme

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CDC: Signs point to an early start for flu season, with cases already ticking up in parts of the U.S.

STAT

Before the Covid-19 pandemic emerged, influenza trackers would begin reading tea leaves around this time of the year, looking for signs of whether there would be an early start to the flu season in the northern hemisphere and which of the various flu viruses might be responsible for the most cases over the coming winter. Flu transmission has been low since the start of the pandemic , but an odd spurt of activity in April, May, and even early June of 2022 — which coincided with the onset o

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Nobel Prize winner Carolyn Bertozzi on revealing the power of chemistry in drug development

PharmaVoice

The Stanford researcher and biotech entrepreneur discusses how click and bioorthogonal chemistry could revolutionize drug development.

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Exelixis announces results from trial evaluating XB002

Pharma Times

Study involves patients with advanced common cancers and solid tumours

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Cloud robotics labs are accelerating drug discovery and development

Pharmaceutical Technology

Drug discovery and development is an incredibly expensive and time-consuming process, taking between 12 and 18 years, and costing on average between $2 billion and $3 billion. Considering the low chances of success, with only 10% of drug candidates making it into clinical development, pharma companies must prevent the increased erosion of profit margins.

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RemeGen receives ODD for myasthenia gravis treatment

European Pharmaceutical Review

RemeGen has announced that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) for its proprietary novel fusion protein Telitacicept (RC18) for the treatment of myasthenia gravis (MG). Telitacicept is a proprietary novel fusion protein from RemeGen to treat autoimmune diseases. It is constructed with the extracellular domain of the human transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) receptor and the fragment crystallisable

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Actinium eyes filing as conditioning drug for AML aces trial

pharmaphorum

Actinium Pharma is on course to submit its targeted radiotherapy for acute myeloid leukaemia (AML) patients needing a bone marrow transplant in the US, buoyed by top-line data from a pivotal trial. The New York biotech said today that the SIERRA trial of Iomab-B – an antibody armed with a radioisotope designed to deliver targeted treatment to tumours and spare healthy tissues – met its primary objective.

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Could monkeypox infections have long-term consequences?

STAT

Since the world began confronting a global outbreak of monkeypox in the spring, the scientific community has had plenty of reasons to rue the fact that for decades this virus has been understudied. Here’s another one: Because of that oversight, doctors treating people who have been infected with monkeypox can’t answer with certainty whether some of them will face any long-term health consequences, referred to as sequelae in the field of medicine.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.