Sat.May 25, 2024 - Fri.May 31, 2024

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NIH documents show how $1.6 billion long Covid initiative has failed so far to meet its goals

STAT

More than three years ago, the National Institutes of Health launched a $1 billion-plus initiative to find the root causes and potential treatments for long Covid , the chronic disease that has quickly changed the lives of millions of Americans. But a lack of visible progress from the initiative, called RECOVER, has drawn months of criticism from patient advocates, researchers, and lawmakers, including at a Senate hearing last week on the NIH’s budget.

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As Senate’s gaze lands on patents, a former US PTO chief calls the effort a ‘broad misunderstanding’

PharmaVoice

To lower drug prices, lawmakers are turning to the drug patent system to outlaw some common practices — but a former patent agency director says it’s the wrong way to go.

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COVID-19 vaccinations now ‘alarmingly low’ in Europe

pharmaphorum

COVID-19 vaccination rates have fallen precipitously in Europe and should be ramped up this autumn so they are at least in line with influenza vaccine uptake.

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Interview: Has Cybin hit the biggest breakthrough in 40 years to treat psychiatric disorders?

Outsourcing Pharma

In an intriguing interview with Cybinâs CEO, Doug Drysdale, OSP senior editor, Liza Laws found out how second-generation psychedelics could be the biggest breakthrough in psychiatry in 40 years.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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A third U.S. farm worker infected with bird flu is the first to experience respiratory symptoms

STAT

A third human case of H5 bird flu tied to the ongoing U.S. outbreak in cattle has been detected in a farm worker in Michigan, state health authorities confirmed on Thursday. The unnamed individual worked on a dairy farm and was in close contact with infected cows, the state health department said in a statement. The farm involved is different from the one where an earlier human case was detected last week.

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Can robots break the cell therapy bottleneck?

PharmaVoice

A partnership between the cell therapy delivery specialist Portal Biotechnologies and precision robotics maker Multiply Labs could bring the manufacturing bottleneck under control, the CEOs said.

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Short reads, big impact: How genomics is revolutionising cancer research

pharmaphorum

Discover how genomics is transforming cancer research through the study of DNA, RNA, and ctDNA. Learn about the latest breakthroughs in the field in this insightful short read.

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The new menstruation: Girls are getting their periods earlier and less regularly

STAT

Menstruation is a critical indicator of health. Whether and when someone with a uterus gets their period — for the first time, and throughout their life — can reflect not only their reproductive health, but their risk of cardiovascular disease, cancer, miscarriage, and premature death. That also makes menstruation a useful measure of population health.

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As weight loss booms, drugmakers look for an edge with oral options

PharmaVoice

Supply of GLP-1 medications falls well short of demand, and oral versions of the drugs loom over Eli Lilly and Novo Nordisk’s dominance.

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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

Polypharmacy, or the concurrent use of at least five medications, can be essential for individuals with multiple chronic conditions. When medications are prescribed with clear therapeutic objectives, optimized to minimize adverse drug reactions (ADRs), and the patient adheres to the regimen, polypharmacy can be appropriate and beneficial. However, it often becomes excessive and hazardous when medications are unnecessary, fail to meet therapeutic goals, pose a high risk of ADRs, or when the patie

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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AZ’s Dato-DXd misses survival endpoint in lung cancer trial

pharmaphorum

The overall survival (OS) data has come in from the TROPION-Lung01 study of AstraZeneca and Daiichi Sankyo’s datopotamab deruxtecan (Dato-DXd) in lung cancer – and the result likely isn’t what they were hoping for.

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The doctor would treat her sickle cell pain crisis — if she promised not to get an abortion

STAT

Here are some things A. was told when she arrived at the hospital one night in June 2023. That she couldn’t have the pain medicine she usually got for a sickle cell crisis because she was six weeks pregnant, but she could have Tylenol. That if she just took her blood thinner everything would be fine. That she needed to leave, and if she still felt bad by the time she’d wheelchaired out into the parking lot, she could turn around and check herself back into the emergency room.

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FTC request may signal trouble for Novo/Catalent deal

PharmaVoice

As Novo Nordisk aims to secure its manufacturing foothold for GLP-1s, regulators are digging for clues of anti-competitive behavior.

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Neurology remains key therapeutic area for Japan pharma majors: GlobalData

Express Pharma

In the dynamic landscape of healthcare, key neurological disorders like Alzheimer’s disease, epilepsy, Parkinson’s disease, and depression pose significant challenges, particularly in the Asia-Pacific (APAC) region, where prevalence is high. The World Health Organization stated in March 2024 that “over 80 per cent of neurological deaths and health losses occur in low- and middle-income countries, and access to treatment varies widely.

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Working for a mature form of genomic medicines

pharmaphorum

In a new episode of the pharmaphorum podcast, Rahul Kakkar, CEO of gene editing company Tome, speaks with web editor Nicole Raleigh about programmable genomic integration (PGI) technology.

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Opinion: The world needs the new pandemic treaty

STAT

At the height of the Covid-19 pandemic, 25 heads of government issued an extraordinary call for a new international treaty for preventing, preparing for, and responding to pandemics. For two years, World Health Organization member states have been negotiating an international agreement scheduled for adoption at the World Health Assembly this month. Yet, late Friday in Geneva, negotiations ground to a halt.

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GP referrals 'key' to Pharmacy First success, analysis suggests

The Pharmacist

Referrals from GP practices and NHS services are ‘key’ to the success of Pharmacy First, the Company Chemists' Association (CCA) has suggested, following its analysis of Pharmacy First consultations around the country. Latest analysis of the number of Pharmacy First consultations in CCA pharmacies across England has suggested disparity between the success of the service […] The post GP referrals 'key' to Pharmacy First success, analysis suggests appeared first on The Pharmacist.

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Merck KGaA announces its largest investment in Asia

Express Pharma

Merck KGaA Darmstadt Germany announced its largest investment in Asia through a ceremony of its € 300 million Bioprocessing Production Center in Daejeon, South Korea. The new facility will accelerate the biotech and pharmaceutical industry’s development by manufacturing vaccines, cell and gene therapies, and protein-based therapies. Once completed, the investment aims to create as many as 300 new jobs and continue to grow and support global demand for critical drugs and therapies.

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This week in clinical trials – 27th to 31st May

pharmaphorum

Stay updated with the latest clinical trials news from 27th to 31st May, featuring companies like Arcturus Therapeutics, AZ, Vesper Bio, Ultragenyx, and Incannex. Get insights into their latest developments and advancements in the field.

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STAT+: For one rare type of lung cancer, Pfizer pill reduces progression by 81%

STAT

There are a lot of reasons why updated data on Pfizer’s Lorbrena, a treatment for non-small cell lung cancer, might not seem to be a big deal. The results are an update on the clinical trial that resulted in the Food and Drug Administration granting Lorbrena full approval in 2001, so in a sense they are not even that new. For Pfizer investors, Lorbrena isn’t that big a deal, either.

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Can robots break the cell therapy bottleneck?

BioPharma Dive

A partnership between cell therapy delivery specialist Portal Biotechnologies and precision robotics maker Multiply Labs could address manufacturing hurdles, the CEOs said.

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Early spike in demand for insect bites advice, suggests NHSE

The Pharmacist

Visits to the NHS England (NHSE) insect bites and stings web page were three times higher in the first three weeks of this month than in the same time period last year, suggesting an early spike in interest, a deputy chief nursing officer (CNO) has said. According to NHSE, the page received a total of […] The post Early spike in demand for insect bites advice, suggests NHSE appeared first on The Pharmacist.

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Update: MSD confirms $3bn takeover of EyeBio

pharmaphorum

MSD has confirmed a $3 billion takeover deal for ophthalmology biotech EyeBio and its drug candidate for diabetic macular oedema (DME) and neovascular age-related macular degeneration (AMD).

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STAT+: Gene therapies for deafness dredge up an old question: Do deaf people want a ‘cure’?

STAT

When Yilai Shu was training to be an otolaryngologist in Shanghai, in the mid 2000s, he often met parents with congenitally deaf kids. “They always asked me, ‘Do you have any drugs to treat our kids?’ said Shu, who is hearing and a professor at Fudan University in China. “That’s what really inspired me to think about developing a drug.

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UK-based company selling breakthrough cannabis-based medicines now supplying the US

Outsourcing Pharma

UK based Celadon Pharmaceuticals Plc, that specializes in the development, production, and sale of breakthrough cannabis-based medicines, announced that it has begun shipping to the US.

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Glenmark creates mass awareness around Hypertension

Express Pharma

Glenmark Pharmaceuticals, marked the month of May as the ‘Hypertension Awareness Month’ by reportedly partnering with more than 1000 healthcare professionals (HCPs) from 250+ cities and towns across the country, and organised 400+ public awareness rallies and screening camps to create mass awareness around Hypertension (High Blood Pressure). The rallies consisted of general informative sessions led by HCPs, who provided detailed insights on the signs, symptoms, and preventive measures related to

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US Congress passes bill to end Parkinson’s disease

pharmaphorum

The US Congress has passed the first-ever federal bill dedicated to ending Parkinson’s disease, modelled on similar legislation for Alzheimer’s enacted in 2011

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STAT+: Many docs who tweeted product endorsements also took money from manufacturers, analysis shows

STAT

Most physicians who endorsed a prescription drug or medical device on X — formerly known as Twitter — also received payments from the manufacturers of these products, according to a new analysis that highlights ongoing concerns about financial ties between doctors and industry. The study found 26 of 28 physicians, or 93%, received at least one payment, and the average was more than $27,400 for such things as food and beverages, speaking, consulting, or travel.

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Sanofi, Formation Bio and OpenAI announce first-in-class AI collaboration

World Pharma News

Sanofi, Formation Bio and OpenAI are collaborating to build AI-powered software to accelerate drug development and bring new medicines to patients more efficiently. The three teams will bring together data, software and tuned models to develop custom, purpose-built solutions across the drug development lifecycle. This represents a first collaboration of its kind within the pharma and life sciences industries.

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Improving stem cell transplantation success in high-risk blood cancers

European Pharmaceutical Review

Repurposing cyclophosphamide may enable more patients with high-risk blood cancers to receive transplanted stem cells from unrelated, partially matched donors, new research suggests. These new findings, which are part of an ongoing Phase II study , will be presented at the 2024 American Society of Clinical Oncology (ASCO) meeting and the European Hematology Association ( Abstract #6503 ).

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AstraZeneca throws its hat into the oral PCSK9 ring

pharmaphorum

AstraZeneca has reported the first clinical data with its oral PCSK9 inhibitor AZD0780, which it hopes could offer an alternative to current injectable drugs used to lower cholesterol.

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STAT+: Duchenne muscular dystrophy drug from Nippon Shinyaku fails in rare confirmatory trial

STAT

Japanese drugmaker Nippon Shinyaku said on Monday that its Duchenne muscular dystrophy drug, Viltepso, part of a controversial class of treatments for the rare disease, had failed to reach its primary endpoint in a placebo-controlled confirmatory trial. Children who received the drug could stand up faster from the floor at the end of the study, but so could children who received a placebo.

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Pharmacies told to plan for October start for autumn Covid jabs

The Pharmacist

NHS England has told community pharmacies providing Covid vaccinations to plan for an ‘early October’ start to the autumn vaccination programme, in a letter published today. It said that it will agree a precise start date for both the flu and Covid jab campaigns ‘in due course’. And with advice from the Joint Committee on […] The post Pharmacies told to plan for October start for autumn Covid jabs appeared first on The Pharmacist.

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Tris Pharma receives USFDA approval for ONYDA XR, a liquid non-stimulant ADHD medication

Express Pharma

Tris Pharma, a commercial-stage biopharmaceutical company focused on attention deficit hyperactivity disorder (ADHD), pain, addiction and neurological disorders, announced the USFDA has approved ONYDA XR (clonidine hydrochloride), a once-a-day extended-release oral suspension with nighttime dosing, for the treatment of ADHD as a monotherapy or as an adjunctive therapy to approved central nervous system (CNS) stimulant medications in paediatric patients six years and older.

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AI is coming and regulators are getting prepared

pharmaphorum

The rise of AI is shaking up the healthcare industry. Learn how the MHRA is working to ensure the safe and effective use of AI in drugs and medical devices.

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