Sat.Mar 02, 2024 - Fri.Mar 08, 2024

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Girls are starting puberty earlier than ever. For some, that comes with major mental health risks

STAT

Zaria was just 9 years old when a nurse practitioner delivered news that rocked her world: The young girl was already showing signs of puberty development, and she was on track to get her period within the next year. Surprised by this timeline, Zaria’s mother, Chanell, worked with a pediatrician to plan healthier meals, hoping that managing her daughter’s weight gain could give her a couple more precious years with her childhood unchanged.

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ACMT Toxicology Visual Pearl: The Bark with Some Bite

ALiEM - Pharm Pearls

Which medication can be derived from the bark of the pictured tree? Aspirin Atropine Colchicine Quinine Reveal the Answer 1. Aspirin Background The photo shows a weeping willow, a member of the Salix genus of trees. Willow tree bark contains salicin from which aspirin (acetylsalicylic acid) can be derived. For over 3500 years, willow bark has been used as a traditional medicine to treat fevers and pain [1].

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Big hopes for schizophrenia treatment rely on a deep pipeline of new approaches

PharmaVoice

Innovation in schizophrenia has been slow, and patients are often left with few options — but pharmas contribute to a robust lineup of candidates that could improve care.

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Women in pharmacy: overcoming imposter syndrome and inspiring inclusion

The Pharmacist

This International Women’s Day focuses on the theme ‘Inspire Inclusion’: championing diversity in leadership and highlighting the experiences of women from all walks of life. The Pharmacist spoke to four female pharmacy leaders to hear how their different experiences of being women and pharmacists have influenced their work and leadership within the profession.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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RSV monoclonal Beyfortus was 90% effective at preventing hospitalizations in children this winter: CDC

STAT

A new monoclonal antibody product to protect against respiratory syncytial virus was 90% effective at preventing little children from being hospitalized with RSV, according to new data from the first season it was in use. The data , published Thursday in Morbidity and Mortality Weekly Report, a Centers for Disease Control and Prevention publication, looked at how well Beyfortus worked in the children whose parents managed to secure a scarce dose of the drug.

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Cannabinoids show promise in acute migraine clinical trial

pharmaphorum

Inhaled cannabinoids have been shown to perform better than placebo in providing pain relief for people suffering from acute migraine in a clinical trial

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Amylyx ALS drug fails crucial study, putting company’s future in doubt

BioPharma Dive

The results have led Amylyx to pause promotion of Relyvrio and potentially pull it from the market in the coming weeks, a major blow to the company and ALS patients.

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STAT+: Nursing home owners can hide nearly two-thirds of their profits, new study shows

STAT

A new study shows that some nursing homes are shunting the majority of their profits off of their own books and into less-visible corners of their owners’ pockets. The practice makes the nursing homes look poorer than they really are, the study’s authors wrote, which seems to bolster the industry’s arguments to Congress that it can’t meet certain proposed quality standards or handle potential Medicare payment cuts.

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Accelerating inclusion in innovation: Gender diversity in clinical research

pharmaphorum

Clinical research continues to struggle with a lack of representation within trial populations, and gender diversity in clinical trials remains a critical issue. Learn about the importance of gender diversity in clinical research trials and how it can accelerate inclusion in innovation.

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Community pharmacy delivers first private covid jabs

The Pharmacist

EXCLUSIVE A community pharmacy in Scotland has delivered what is believed to be the UK’s first private Covid vaccination, ahead of the service’s planned launch date in April. Dear Pharmacy & Travel Clinic was among a number of community pharmacies that received stock of the Pfizer’s private Covid mRNA vaccine earlier than expected, and so […] The post Community pharmacy delivers first private covid jabs appeared first on The Pharmacist.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FDA delays decision on Lilly’s closely watched Alzheimer’s drug

BioPharma Dive

The agency expects to convene a group of outside experts to more closely scrutinize the safety and efficacy of the medicine, donanemab, pushing back the timing of its potential approval.

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STAT+: In stunning outcome, Amylyx’s ALS drug fails large clinical trial

STAT

Amylyx Pharmaceuticals said Friday that its treatment for ALS, called Relyvrio, failed to provide any benefit for patients in a large clinical trial — a stunning outcome that now has the company considering a voluntary withdrawal of the approved medicine from the market. “This is really hard for us, and it’s really hard for our team who care so much, but it’s so much harder for people with ALS and their families, and we have to keep that perspective,” said a so

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Women in life sciences: Miruna Sasu

pharmaphorum

Celebrate International Women’s Day by learning about Miruna Sasu, a prominent female figure in the life sciences field and CEO of COTA. Explore how the company uses AI in the oncology space.

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LACTOSE-Free Medicines: Which Drugs Contain LACTOSE?

Drug Patent Watch

LACTOSE-Free Medicines, 2024 is part of DrugPatentWatch’s deep library of business intelligence on biopharmaceutical drugs. Buy Lactose-Free Medicines from Amazon This guide is designed to provide information for healthcare providers to… The post LACTOSE-Free Medicines: Which Drugs Contain LACTOSE? appeared first on DrugPatentWatch - Make Better Decisions.

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Alnylam, Roche blood pressure drug scores in second mid-stage trial

BioPharma Dive

The study results further validate Roche’s recent decision to acquire rights to the drug, which is being developed for people with a stubborn form of hypertension.

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Florida health officials provide scant details on measles cases, worrying health experts

STAT

On Sunday, public health officials in two Michigan counties warned their residents that they may have been exposed to measles. In Wayne County , an adult who had contracted the virus abroad had been in health-related settings in Dearborn on two days last week — two urgent care clinics, a CVS pharmacy, and a hospital emergency department. Health officials in neighboring Washtenaw County issued a similar alert about a different case — also an adult, also infected abroad —

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Bridging the gap: Uniting stakeholders through a digital ecosystem for holistic maternity care

pharmaphorum

Discover how a digital ecosystem can unite stakeholders in providing holistic maternity care, enhance maternal and postpartum care outcomes, and bridge the gap in healthcare services.

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High ADHD comorbidity rates offer opportunity for pipeline products to capture market: GlobalData

Express Pharma

Attention-deficit/hyperactivity disorder (ADHD) is a clinically heterogenous neurodevelopmental disorder with high rates of comorbidity with other childhood-onset psychiatric disorders as well as learning disorders. As a result, pipeline products capable of targeting both ADHD and comorbid symptoms will have a competitive edge to capture a highly saturated ADHD market, says GlobalData.

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Bayer pays $310M to buy into BridgeBio heart drug

BioPharma Dive

The deal gives the German pharma partial rights to a closely watched medicine for transthyretin amyloidosis cardiomyopathy that analysts expect to become a multibillion-dollar product.

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Microplastics found in blood vessels linked to greater risk of heart problems, study finds

STAT

Micro and nanoplastics, tiny pieces of plastic scattered throughout the environment, have been increasingly found to be able to enter the body, raising questions about where they end up and how they affect people’s health. In a new study, researchers say they have for the first time detected these plastic pieces inside fatty plaques that accumulate in blood vessels and linked them to an increased rate of heart problems.

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Women in life sciences: Angie Franks

pharmaphorum

Angie Franks is a prominent female figure in the life sciences industry and perfect to highlight on International Women's Day. Learn more about her contributions and achievements in healthcare and technology.

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GELATIN-Free Medicines: Which Drugs Contain GELATIN?

Drug Patent Watch

GELATIN-Free Medicines, 2024 is part of DrugPatentWatch’s deep library of business intelligence on biopharmaceutical drugs. Buy Gelatin-Free Medicines on Amazon This guide is designed to provide information for healthcare providers to… The post GELATIN-Free Medicines: Which Drugs Contain GELATIN? appeared first on DrugPatentWatch - Make Better Decisions.

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Oncology emerges as dominant therapy area for CRISPR technology

Pharmaceutical Technology

In late 2023, the Medicines and Healthcare products Regulatory Agency approved Vertex’s Casgevy, which became the inaugural clustered regularly interspaced short palindromic repeats (CRISPR)-based drug for the haematological indications beta thalassemia and sickle cell disease (SCD).

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Opinion: Free tuition won’t fix medicine’s diversity problem without admissions reform

STAT

Medical students at Albert Einstein School of Medicine in New York City gathered last week to hear a life-changing announcement: Ruth Gottesman revealed she would be donating $1 billion, ensuring no student at Einstein will pay tuition ever again. Leadership at Albert Einstein School of Medicine celebrated the donation as a means to attract a more diverse student body.

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12 Questions with Jorge Reis-Filho

pharmaphorum

Get to know Jorge Reis-Filho, Vice President of Cancer Biomarker Development at AstraZeneca, through this exclusive interview featuring 12 insightful questions. Gain insights into his role, career journey, and the latest advancements in cancer biomarker development.

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Oncology dominates CRISPR landscape: GlobalData

Express Pharma

The Medicines and Healthcare products Regulatory Agency (MHRA) approved Vertex ’s exagamglogene autotemcel (Casgevy) in late 2023. Subsequently, it became the inaugural CRISPR-based drug for the hematological indications beta thalassemia and sickle cell disease (SCD). Despite this approval, the CRISPR landscape is dominated by oncology, which accounts for 30 per cent of all active CRISPR drugs.

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FDA approves J&J’s Rybrevant with chemotherapy for NSCLC treatment

Pharmafile

Johnson & Johnson have announced that the US Food and Drug Administration (FDA) has approved Rybrevant (amibantamab-vmjw) following a priority review. The drug has been approved in combination with chemotherapy (carboplatin-pemetrexed) for the first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 […] The post FDA approves J&J’s Rybrevant with chemotherapy for NSCLC treatment appe

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STAT+: Amylyx ALS drug failure leaves patients, advocates, and researchers reeling — and wondering what’s next

STAT

The latest disappointment in amyotrophic lateral sclerosis research brought crushing news for patients and physicians, forcing the community to consider just what to do with an approved medicine that doesn’t appear to work. Amylyx Pharmaceuticals’ announcement Friday that its drug, marketed as Relyvrio, failed to beat placebo in a pivotal study marks “a sad day for us, but we have to believe the data,” said Mary Catherine Collet, an ALS advocate.

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How natural language processing can make a difference in pharma

pharmaphorum

On today’s podcast, host Jonah Comstock welcomes Jane Reed, director of life sciences at IQVIA NLP, the new name for recent IQVIA acquisition Linguamatics. Reed talks through some of these different technologies and use cases and describes how natural language processing has exciting potential in translating real-world conversations on social media into pharmaceutical adverse event reports.

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New patent expiration for Takeda Pharms drug ULORIC

Drug Patent Watch

Annual Drug Patent Expirations for ULORIC Uloric is a drug marketed by Takeda Pharms Usa and is included in one NDA. It is available from one supplier. There are three… The post New patent expiration for Takeda Pharms drug ULORIC appeared first on DrugPatentWatch - Make Better Decisions.

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NodThera says inflammation drug has positive effect in Parkinson’s

BioPharma Dive

The results from the privately held biotech add to early evidence supporting the potential of an increasingly popular drug target known as NLRP3 inflammasomes.

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How the U.S. is sabotaging its best tools to prevent deaths in the opioid epidemic

STAT

The opioid overdose epidemic has burned through the U.S. for nearly 30 years. Yet for all that time, the country has had tools that are highly effective at preventing overdose deaths: methadone and buprenorphine. These medicines are cheap and easy to distribute. People who take them use illicit drugs at far lower rates, and are at far lower risk of overdose or death.

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GSK scores again with Blenrep in multiple myeloma

pharmaphorum

GSK continues to build the case for its multiple myeloma therapy Blenrep, which was pulled from the US market last year, with another positive phase 3 trial. The BCMA-targeted antibody-drug conjugate (ADC), given in a regimen with pomalidomide plus dexamethasone (PomDex), was shown to be more effective at preventing disease progression or death than Johnson & Johnson’s $10 billion-a-year anti-CD38 antibody Darzalex (daratumumab) with PomDex in the head-to-head DREAMM-8 trial.

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Navigating the Current Funding Slowdown While Securing Capital

Pharmaceutical Commerce

In this Pharmaceutical Commerce video interview, Emma Banks, CEO of ramarketing, discusses the biggest roadblocks to the widespread adoption of novel modalities, and how new biotech companies can navigate the current funding slowdown while securing the capital crucial for their success.

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Boundless Bio, a Bayer-backed cancer biotech, seeks an IPO

BioPharma Dive

The startup, which has raised nearly $254 million privately, is in early testing with drugs designed to target particularly tough-to-treat tumors.

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