Sat.Feb 10, 2024 - Fri.Feb 16, 2024

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STAT+: In ‘major milestone,’ FDA approves first cell therapy for solid tumors

STAT

Nearly four decades after its first conception, the first TIL therapy, an immunotherapy that harvests cancer-fighting immune cells from the patient’s own body, received accelerated approval from the Food and Drug Administration for advanced melanoma. The therapy, called Amtagvi or lifileucel from Iovance, is the first cell therapy approved for a solid tumor.

Immunity 363
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Pharma CFOs need vigilance in tough economic times

PharmaVoice

Belt tightening and streamlined portfolios are critical in 2024 amid continued economic uncertainty.

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Trending Sources

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Positive results for MAIA’s SCLC treatment published in Nature Communications

Pharma Times

The aggressive type of cancer accounts for 13% of all lung cancer cases worldwide

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SAEM Clinical Images Series: An Ultrasonographic Rabbit Hole

ALiEM - Pharm Pearls

An 86-year-old man with a past medical history of coronary artery disease, hypertension, hyperlipidemia, chronic kidney disease, COPD, choledocholithiasis requiring ERCP and sphincterotomy 2 years ago presented with five days of feeling unwell. History was limited due to cognitive impairment. His daughter had reported to staff he had been feeling unwell for five days, intermittently having nausea and generalized abdominal pain, subjective fevers, chest pain, and shortness of breath.

Hospitals 161
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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Opinion: Independent doctors like me are becoming an endangered species

STAT

More than 100,000 doctors have  left private practice  and become employees of hospitals and other corporate entities since 2019. Today, nearly  three in four physicians  are employees of larger health care entities or other corporations — a record high. As an independent physician, I know exactly why so many are making that choice.

Hospitals 363
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3 questions hanging over the Novo-Catalent deal

PharmaVoice

As backlash builds for the recently announced matchup, critical questions remain over its impact.

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MHRA agrees licence change for Pfizer-BioNTech’s Comirnaty vaccine

Pharmaceutical Technology

The UK MHRA has granted approval for a variation in licence of Pfizer-BioNTech’s Comirnaty XBB.1.5 vaccine targeting Omicron variant.

Vaccines 142
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Juul’s internal playbook opens a rare window into influence in Washington

STAT

WASHINGTON — A new trove of internal emails and other documents from the e-cigarette maker Juul reveals the company’s extensive behind-the-scenes efforts to promote its interests in Washington — a rare insight into the otherwise opaque methods corporations use to influence the government. It’s well documented that Juul spent significant sums on registered lobbyists and political donations back in 2018 and 2019, when the head of the Food and Drug Administration declare

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A new (old) mind-opening tool in the fight against Alzheimer’s disease

PharmaVoice

A new use for an existing ultrasound technology is seeing early success in getting medications past the blood-brain barrier.

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Closed Loop Medicine shares results of proprietary technology for hypertension

Pharma Times

CLM-HT01 improved blood pressure and minimised adverse reactions in patients

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Mounjaro weight loss service hoped to ease supply issues

The Pharmacist

Hundreds of community pharmacies have begun offering a tirzepatide injection as part of a new weight loss service beginning this week. The move follows the approval of a new four-dose version of Mounjaro last month. It is hoped that the new service will expand the availability of private weight-loss treatments amid ongoing shortages of alternatives […] The post Mounjaro weight loss service hoped to ease supply issues appeared first on The Pharmacist.

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STAT+: A flurry of research misconduct cases has universities scrambling to protect themselves

STAT

There was a time when an allegation of data mishandling, scientific misconduct, or just a technical error felt like a crisis to Barrett Rollins, an oncologist and research integrity officer at Dana-Farber Cancer Institute. Now, it’s a Tuesday. The renowned cancer treatment and research center is in the midst of a lengthy review of possible discrepancies involving around 60 papers co-authored by four of its top researchers over a period of over 15 years, including CEO Laurie Glimcher and C

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FDA inches closer to defining its regulatory role in AI

PharmaVoice

Commissioner Dr. Robert Califf signals how the FDA will consider AI in drug development and how the agency may use the emerging technology in the future.

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NIHR awards over £20m to eight new global health research projects

Pharma Times

The projects will focus on healthcare in LMICs in the event of extreme weather

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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GPhC announces five new council members

The Pharmacist

The General Pharmaceutical Council (GPhC) has announced the appointment of five new members to its governing council, including a community pharmacist. Adeyemi (Ade) Williams, superintendent pharmacist and director of M J Williams Pharmacy, and lead pharmacist at the Bedminster Pharmacy, Bristol, will begin his term on 1 April 2024. Joining him will be Professor Dianne […] The post GPhC announces five new council members appeared first on The Pharmacist.

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Stem cell study offers clue to South Asians’ increased risk of cardiovascular disease

STAT

A growing body of data show that South Asians are at greater risk of developing heart disease than white people, and they tend to get complications at younger ages, but it’s not been fully clear what explains this disparity. A new study suggests one potential reason is that South Asians have a decreased ability to repair blood vessels that get injured from cardiovascular problems.

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‘Hey, AI: Is Zoloft effective for me?’ Tech’s foray into predictive prescribing

PharmaVoice

Researchers are unleashing the powers of AI for precision medicine, drug development and more.

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Scientists develop micofluidic chip to make cell therapy safer

Pharma Times

The chip removes cells, which could become tumours, before they are implanted in a patient

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Transforming drug development with AI

pharmaphorum

Discover how artificial intelligence (AI) is revolutionising the drug development process and transforming the way FDA-approved drugs are produced, ensuring compliance and optimising the supply chain. Learn more about the future of AI in pharmaceuticals.

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STAT+: For unlucky mountaineers, tundra explorers and the unhoused, a new drug could avert the ravages of frostbite

STAT

Two days after his right hand froze, Hart Bezner realized for the first time that he might lose it.  The retired physics professor was sitting in an emergency room in Whitehorse, the capital of Canada’s Yukon territory, where two doctors and a pharmacist were taking an unusual amount of interest in the appendage and the pink blisters that now covered it.

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‘I wish I could see the end of the day’ — a Pfizer exec on the fight for health equity

PharmaVoice

The pharma giant’s leader of a collective devoted to health equity discusses how companies can put their money where their mouth is to reach communities in need.

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Phesi’s AI-driven Trial Accelerator platform contains over 100 million patients

Pharma Times

The platform delivers digitalised patient data to improve clinical trials and development

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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Alnylam change to heart drug trial sparks doubts, sinking shares

BioPharma Dive

Analysts pressed Alnylam executives on the reasons for the changes to HELIOS-B, a Phase 3 study in ATTR amyloidosis with cardiomyopathy that is important to the company’s future.

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Smoking impairs immune response, even after quitting, new study says

STAT

Public health messages have told us for decades that if you smoke, you should quit. And if you don’t smoke, don’t start. But a new study suggests smoking may be even worse than we thought. The study , published Wednesday in Nature, underscores the importance of never lighting up that first cigarette, based on its conclusion that smoking has much longer harmful effects on immune responses than previously understood.

Immunity 361
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Quarter of all Covid vaccines administered in community pharmacies

The Pharmacist

Almost two-thirds (62%) of Covid-19 vaccines were administered in community pharmacies in December 2023, according to the Company Chemists’ Association (CCA). The CCA’s analysis, based on data from NHS England and Freedom of Information requests, found that community pharmacy had administered more than 40 million Covid-19 vaccinations by the end of 2023 – a quarter […] The post Quarter of all Covid vaccines administered in community pharmacies appeared first on The Pharmacist.

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Researchers investigate new technique for diagnosing cardiac conditions

Pharma Times

Cardiac quantitative susceptibility mapping successfully visualised iron deposits in patients

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Women’s health is a priority not a charity

pharmaphorum

Investing in women's health research and funding is not a charity, but a priority. Discover the importance of allocating resources and supporting initiatives that promote women's health and well-being.

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Covid-19 vaccine confidence soured by officials’ messaging, Republicans argue

STAT

WASHINGTON — A House hearing on vaccine safety claims sought to pierce through Americans’ falling confidence in routine shots and the spread of Covid-19 misinformation — sometimes from people in the room. The latest hearing before the House Select Subcommittee on the Coronavirus Pandemic comes amid a global drop in vaccinations, even routine childhood inoculations.

Vaccines 360
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Sage offers details on launch of new postpartum depression pill

BioPharma Dive

The company and partner Biogen say signs from payers and doctors suggest the launch of Zurzuvae, the first oral therapy for PPD, is off to a good start.

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Neurona secures $120m to advance lead cell therapy candidate for epilepsy

Pharma Times

NRTX-1001 is being assessed for drug-resistant mesial temporal lobe epilepsy

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.