Sat.Mar 11, 2023 - Fri.Mar 17, 2023

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Polio cases derived from new oral vaccine reported for first time

STAT

Experts have long understood that a new polio vaccine developed to try to minimize the risks associated with the oral polio vaccine made by Albert Sabin might also cause the problem it was created to sidestep. It’s now clear that theoretical risk is a real one. The Global Polio Eradication Initiative announced Thursday that six children in the Democratic Republic of the Congo and one in Burundi have been paralyzed by viruses from the new vaccine, which is referred to as novel oral polio v

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A rising oncology powerhouse in China, BeiGene looks to strengthen its international punch

PharmaVoice

To expand its reach, Christiane Langer, the company’s head of medical affairs, is leaning on connections and singularity over fitting in a box.

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LEO Pharma and ICON enter a Strategic Partnership on clinical trial mission

LifeProNow

March 10, 2023 : “LEO Pharma, a global leader in medical dermatology, and ICON plc announced a strategic partnership that will enable LEO Pharma to scale clinical trial execution that is patient-centric and cost effective, and which will support the company’s overall ambition of building one of the most effective and efficient clinical portfolio execution organisations in the industry.

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Owlstone Medical collaborates with Bicycle Therapeutics

Pharma Times

Duo team up for the development of antigen-targeted probes for early cancer detection

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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Denied by AI: How Medicare Advantage plans use algorithms to cut off care for seniors in need

STAT

An algorithm, not a doctor, predicted a rapid recovery for Frances Walter, an 85-year-old Wisconsin woman with a shattered left shoulder and an allergy to pain medicine. In 16.6 days, it estimated, she would be ready to leave her nursing home. On the 17th day, her Medicare Advantage insurer, Security Health Plan, followed the algorithm and cut off payment for her care, concluding she was ready to return to the apartment where she lived alone.

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Babson aims to shed Theranos curse with new blood testing tech

PharmaVoice

Babson Diagnostics is trying to create a less invasive blood testing technology — can it gain trust in the post-Theranos era?

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Immutep reveals initiation of pivotal Efti study

Pharma Times

The clinical trial also involves paclitaxel in the treatment of metastatic breast cancer

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JAMA’s new editor settles in, bringing open access and other changes

STAT

ST. LOUIS — It’s been eight months since Kirsten Bibbins-Domingo, a general internist, cardiovascular researcher, and epidemiologist became the 17th editor in chief of the Journal of the American Medical Association and its network of journals. Bibbins-Domingo, who previously worked at the University of California, San Francisco, was named this week as a member of the 2023 STATUS List of people making a difference in health care and life sciences.

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Across therapy areas, GoodRx’s POS rebates improve access and affordability for cash-paying patients

PharmaVoice

Across therapy areas, GoodRx Assist is a proven point-of-sale rebate program for cash-paying patients.

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Sanofi to acquire Provention Bio, adding to portfolio TZIELD for type diabetes (T1D)

LifeProNow

March 13, 2023 : “Sanofi and Provention Bio, Inc., a U.S.-based, publicly traded biopharmaceutical company focused on intercepting and preventing immune-mediated diseases including type 1 diabetes (T1D), have entered into an agreement under which Sanofi has agreed to acquire Provention Bio, Inc., for $25.00 per share in cash, representing an equity value of approximately $2.9 billion.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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iOnctura reveals roginolisib research results

Pharma Times

Therapy prevents tumour proliferation while breaking immune tolerance among cancer patients

Immunity 137
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‘I’m terrified’: Patients scramble for treatment after 13 ketamine clinics shut down

STAT

Around 4:30 p.m. last Friday, Ketamine Wellness Centers CEO Kevin Nicholson sent an email: In 30 minutes, the company would no longer be in business, he said. The message went out to some patients and to all of the employees of his company’s clinics across nine states — what had, up until moments before, been one of the largest ketamine clinic chains in the country.

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A biopharma CEO’s quest for global health equity has put him in the running for a Nobel Prize

PharmaVoice

Dr. Ryan Saadi, CEO of Tevogen Bio, is making good on a lifelong goal of bringing T cell therapies to people who need them.

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FDA reversal sets up high-stakes hearing on Sarepta gene therapy

BioPharma Dive

The regulator will convene a panel of advisers to consult on an approval decision for the biotech’s Duchenne treatment, a change from just a few weeks ago when Sarepta had said a meeting wouldn’t be held.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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NICE approves funding for Novartis gene therapy

Pharma Times

Funding is for onasemnogene abeparvovec and concerns babies with spinal muscular atrophy

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FDA offers radio silence on question of spring Covid boosters, as other countries push ahead

STAT

Are you six months out from your Covid-19 bivalent booster and wondering when you’ll be able to get another shot? If you live in the United Kingdom or Canada, you already have your answer. The Canadian and U.K. governments, acting on recommendations from expert committees, plan to offer spring booster shots for people at highest risk of getting severely sick from Covid.

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In the fallout from Aduhelm, Biogen’s leadership shakeup continues

PharmaVoice

The recent departure of neurodegenerative development head Samantha Budd Haeberlein is just the latest sign of a changing tide among Biogen’s post-Aduhelm leadership.

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Top 10 Journal Articles To Read During Your Infectious Diseases Pharmacy Rotation

ID Stewardship

In this post a top 10 list of journal articles to read during an infectious diseases pharmacy rotation is provided. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article Posted 12 March 2023 As a pharmacist serving as a preceptor to students and residents in the area of infectious diseases since 2010, I have always been on the hunt for good infectious diseases journal articles for my learners to read.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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PBD Biotech reveals vital update to TB test

Pharma Times

Lyophilized PCR reaction bead reduces the cost of transport and extends shelf life for the test

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Opinion: The staggering financial burden of a proposed HIPAA rule

STAT

The already beleaguered U.S. health care system is facing a new and costly threat that will affect patient care and ultimately may lead to hospital closures : paying for and processing a torrent of medical record requests. While the news media in 2022 focused on hospitals’ billions of dollars of losses , negative operating margins, and other daunting post-pandemic challenges , a set of costly modifications to the HIPAA Privacy Rule proposed by the Department of Health and Human Services m

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Return of the megadeal: Pfizer’s Seagen buy has the industry asking if super-sized M&A is back

PharmaVoice

A $43 billion deal that doubles the pharma giant's cancer pipeline shows that M&A is back on the table in pharma.

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Pfizer to acquire Seagen for $43 billion

European Pharmaceutical Review

Pfizer has announced it will acquire Seagen Inc. for a total enterprise value of $43 billion. “Together, Pfizer and Seagen seek to accelerate the next generation of cancer breakthroughs and bring new solutions to patients by combining Seagen’s antibody -drug conjugate (ADC) technology… with Pfizer’s capabilities and expertise,” shared Dr Albert Bourla, Pfizer Chairman and Chief Executive Officer.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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IIH headaches could be treated with exenatide

Pharma Times

The type 2 diabetes therapy is being tested on patients in a phase 2 clinical trial

Diabetes 137
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Large network of clinics offering ketamine for depression shuts down

STAT

One of the largest operators of ketamine clinics in the country abruptly closed its facilities this week, leaving patients in the dark and out of treatment for depression and other chronic conditions. Ketamine Wellness Centers spanning nine states were shuttered, leaving laid-off employees and patients with more questions than answers. Interest in ketamine to treat depression and other conditions has grown in recent years.

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The PharmaVoice 100 — Who makes the cut

PharmaVoice

What we’re looking for in each new class of honorees.

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GOSH and Leucid to manufacture novel CAR T therapy

European Pharmaceutical Review

In a first-of-its-kind commercial agreement, Great Ormond Street Hospital NHS Foundation Trust (GOSH) will work with Leucid Bio to manufacture LEU011, a lateral Chimeric Antigen Receptor (CAR) targeting NKG2D ligands. The CAR T therapy will be used in clinical studies for solid tumours and haematological malignancies. Under the agreement the parties will work together at state-of-the-art cleanroom facilities at the Zayed Centre for Research into Rare Disease in Children.

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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Acesion announces positive atrial fibrillation study

Pharma Times

Candidate AP30663 is an inhibitor for the conversion of atrial fibrillation to a normal sinus rhythm

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STAT+: U.K. trade group suspends Novo Nordisk for ‘serious breaches’ in promoting obesity drug

STAT

In a rare move, a U.K. pharmaceutical industry trade group suspended Novo Nordisk for two years due to “serious breaches” involving the promotion of a weight-loss drug that violated a code of practice and discredited the entire sector. The Association of the British Pharmaceutical Industry took this step after receiving a complaint alleging the company had sponsored courses on weight management on LinkedIn for health professionals, without making clear that it was involved in the s

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Woman of the Week: Novartis Gene Therapies’ Chris Fox

PharmaVoice

Welcome to the Woman of the Week podcast, a weekly discussion that illuminates the unique stories of women leaders who are catalyzing change throughout the life sciences industry. You can check out all our podcast episodes here. When Novartis acquired AveXis and its spinal muscular atroph.

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Brazil’s ANVISA approves Takeda’s dengue vaccine candidate Qdenga

Pharmaceutical Technology

The National Health Surveillance Agency (ANVISA) in Brazil has granted approval for Takeda ’s dengue virus vaccine candidate, Qdenga (Dengue Tetravalent Vaccine [Live, Attenuated]) (TAK-003). The vaccine has received approval for preventing dengue disease in people aged four years to 60 years. Qdenga has been developed based on a live-attenuated dengue serotype 2 virus that offers the genetic backbone for four dengue virus serotypes and is designed to provide protection against any of these.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.