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STAT+: Cogent Biosciences drug improves symptoms of chronic immune disorder, study results show

STAT

Cogent Biosciences said Monday that its experimental drug reduced the symptoms of a chronic immune disorder called indolent systemic mastocytosis. The results mean the drug achieved the goals of a Phase 3 study, but a comparison to a rival treatment from Blueprint Medicines remains muddled. 

Immunity 231
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Childhood vaccination coverage was falling across the globe even before Covid

STAT

The study, which estimated childhood vaccination coverage between 1980 and 2023 in 204 countries and territories, found that the Covid-19 pandemic significantly intensified existing immunization challenges. Read the rest…

Vaccines 359
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Cassidy calls to delay meeting of CDC’s vaccine panel in challenge to RFK Jr.

STAT

“Although the appointees to [the Advisory Committee on Immunization Practices] have scientific credentials, many do not have significant experience studying microbiology, epidemiology or immunology. Kennedy Jr. to be delayed, citing their lack of experience and potential bias against some vaccines.

Vaccines 364
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Cassidy says RFK Jr. briefed him on HHS job cuts, but reported study on vaccines, autism didn’t come up

STAT

And while the meeting took place two days after a report that the department had tapped vaccine critic David Geier to conduct a study looking for a link between immunizations and autism, the Louisiana senator said that issue did not come up.      Read the rest…

Vaccines 358
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STAT+: Cancer therapy’s new ‘gold rush’:  bispecific antibodies that hit key combination of targets

STAT

Immune checkpoint inhibitors, drugs that can help make the immune system recognize and destroy cancer more aggressively, are one of the most important medicines in cancer treatment today.

Immunity 361
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STAT+: Insurance coverage of vaccines at risk in RFK Jr.’s reshuffling of CDC’s vaccine advisers

STAT

Right now, anyone with health insurance — adults and children alike — who wants a vaccine that is recommended by the Advisory Committee on Immunization Practices can get it for free. It could also take money out of Americans’ wallets.

Vaccines 341
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Osivax publishes phase 2a results supporting dual flu vaccine approach

Pharma Times

The results, now published in Vaccines , show that the combination was well-tolerated with no serious adverse events, and generated strong immune responses. Robust NP-specific humoral and cell-mediated immune responses were observed in all participants given OVX836, whether alone or with Fluarix Tetra.