STAT

MARCH 5, 2024

In 2003, the year Nora Volkow was appointed director of the National Institute on Drug Abuse, roughly 4,000 Americans died of opioid overdose. In the two decades since, the overdose crisis has morphed into a full-fledged public health emergency, with 80,000 Americans dying from opioid overdoses each year. treats opioid addiction.

265

265

STAT

JANUARY 10, 2023

Five studies co-authored by Tessier-Lavigne are now under the microscope for containing alleged altered images: a 1999 Cell study , a 2008 paper in the EMBO Journal, a 2003 Nature study, and two studies published in 2001 in Science.

330

330

STAT

JUNE 1, 2023

billion in 2003 to $42.9 But that could end up hammering the NIH budget, which has steadily climbed over the years as Congress channeled billions of dollars to research on cancer, Alzheimer’s disease, and rare diseases. The NIH’s overall budget nearly doubled from $25.8 billion in 2022.

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239

STAT

MARCH 6, 2023

That was the message Chinese scientists delivered Monday on the opening day of the Third International Summit on Human Genome Editing in London.

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238

STAT

JANUARY 30, 2023

The human genome was sequenced in 2003. The act also created an industry that didn’t exist in the United States before its enactment, enabling the formation of companies to develop and commercialize therapies for rare diseases. That said, a lot has changed in science and drug development since 1983.

Drug Development 228

Drug Development 228

STAT

JULY 5, 2023

Both are run by a husband-and-wife team that has received more than $17 million in NIH funding since 2003, according to the animal rights group. ” The move came more than six months after the People for the Ethical Treatment of Animals notified both the U.S.

Vaccines 231

Vaccines 231

STAT

APRIL 15, 2024

Advisors, a hedge-fund firm run by brothers Felix and Julian Baker, had in 2003 invested in Seagen, a developer of next-generation cancer treatments. Pfizer bought Baker Bros.  Pfizer bought the company for $43 billion last year.

227

227

STAT

JANUARY 27, 2023

biomedical research powerhouse, a role he held from 2003 to 2021, when he was appointed to serve as the White House’s first Cabinet-level science adviser to the president. But the founding director will not be back at the helm of the Cambridge, Mass.,

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224

Express Pharma

APRIL 22, 2024

The group now has 393 approvals and has so far filed over 460* ANDAs since the commencement of the filing process in FY 2003-04. Mirabegron Extended-Release Tablets USP 25mg and 50mg had annual sales of $2.42 billion in the US (IQVIA MAT February 2024). The post Zydus launches Mirabegron ER tablets in US appeared first on Express Pharma.

98

98

STAT

NOVEMBER 1, 2022

The precedent established in 2003, when the court ruled that race, along with other factors, could be given limited consideration in higher education admissions when necessary to achieve student body diversity, is now in jeopardy.

Medical Schools 257

Medical Schools 257

STAT

NOVEMBER 8, 2022

In 2003, Pancho’s life changed forever. That’s when a car crash sent the 20-year-old farm worker into emergency surgery to repair damage to his stomach. The operation went well, but the next day, a blood clot caused by the procedure cut off oxygen to his brain stem, leaving him paralyzed and unable to speak.

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246

Pharmacy Times

FEBRUARY 16, 2024

This marks omalizumab’s fourth FDA-approved indication for allergic and inflammatory conditions, such as severe persistent allergic asthma, with its initial approval being in 2003.

57

57

Express Pharma

FEBRUARY 9, 2024

The group now has 387 approvals and has so far filed over 460* ANDAs since the commencement of the filing process in FY 2003-04. Dexamethasone Tablets USP, 1 mg had annual sales of $1.8 million in the United States (IQVIA Dec. The post Zydus gets tentative USFDA approval for Dexamethasone Tablets USP, 1 mg appeared first on Express Pharma.

Immunity 91

Immunity Immunization 91

cureatr

AUGUST 10, 2023

Two decades after the Medicare Modernization Act of 2003 created Medicare Part D, nearly 50 million Americans are enrolled in a standalone prescription drug benefit program.

Medication Therapy Management (MTM) 78

Medication Therapy Management (MTM) 78

STAT

SEPTEMBER 22, 2023

Yale and the VA agreed in 2003 to share royalties on patents with inventors from both institutions.  Yale and professor John Krystal agreed to pay $1.5 million to resolve claims that they failed to pay the VA its share of royalties for patents covering intranasal ketamine used to treat depression.

Department of Veterans Affairs 224

Department of Veterans Affairs Pharmacy Technician Compounding Pharmacies Compounding 224

Express Pharma

FEBRUARY 8, 2024

The group now has 386 approvals and has so far filed over 448* ANDAs since the commencement of the filing process in FY 2003-04. Dexamethasone Tablets USP, 0.5 mg, 4 mg and 6 mg had annual sales of $22 million and Dexamethasone Tablets USP, 2 mg has annual sales of $6 million in the United States (IQVIA Dec.

101

101

Outsourcing Pharma

JUNE 7, 2021

The US Food and Drug Administration (FDA) has approved Biogenâs Aduhelm (aducanumab) for the treatment of Alzheimerâs: making it the first new treatment approved for the disease since 2003.

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98

Express Pharma

JANUARY 25, 2024

The group now has 384 approvals and has so far filed over 448* ANDAs since the commencement of the filing process in FY 2003-04. Gabapentin Tablets (Once-Daily), 300 mg and 600 mg had annual sales of $85 million in the United States (IQVIA Nov.

81

81

Orsini Pharmacy

FEBRUARY 27, 2023

In 2003, Tommy was diagnosed with Duchenne Muscular Dystrophy (DMD) , a genetic disorder where the body does not maintain muscle mass due to an inborn lack of the protein dystrophin. On Rare Disease Day, we are dedicating this blog to Tommy, a selfless and caring individual we had the opportunity to serve for several years.

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85

NY Times

JUNE 5, 2021

If the agency approves it, aducanumab would be the first new Alzheimer’s treatment since 2003. Patients are desperate for new options, but some scientists say there isn’t enough evidence it works.

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81

Express Pharma

APRIL 19, 2023

The group now has 363 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. Roflumilast Tablets, 250 mcg had annual sales of $34 million in the United States (IQVIA MAT Feb. The post Zydus gets USFDA approval for Roflumilast Tablets, 250 mcg appeared first on Express Pharma.

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92

Express Pharma

NOVEMBER 30, 2023

The group now has 382 approvals and has so far filed over 448* ANDAs since the commencement of the filing process in FY 2003-04. Ivabradine Tablets, 5 mg and 7.5 mg had annual sales of $136.5 million in the United States (IQVIA MAT October,2023). The post Zydus gets US FDA final approval for Ivabradine Tablets, 5 mg and 7.5

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Pharma Mirror

OCTOBER 4, 2021

In 2003 the Human Genome Project provided the first atlas. Despite untold investment by numerous pharmaceutical companies, FDA-approved drugs that target critical brain functions and conditions like anxiety, depression, and sedation continue to present severe and unpredictable side effects, including suicidal ideation.

Pharmaceutical Companies 119

Pharmaceutical Companies Pharmaceutical Companies 119

The Guardian - Pharmaceutical Industry

SEPTEMBER 9, 2023

Now many believe the money might have been better spent on public health interventions After spending 13 years and $2.7bn, the Human Genome Project announced in 2003 that it had successfully mapped our DNA, paving the way for a new era of medicine that would deliver “the right treatment, for the right patient, at the right time”.

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59

Express Pharma

AUGUST 31, 2023

The group now has 378 approvals and has so far filed over 444 ANDAs since the commencement of the filing process in FY 2003-04. Isotretinoin Capsules USP, 10 mg, 20 mg 30 mg and 40 mg had annual sales of $165 million in the United States (IQVIA MAT July 2023).

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93

Express Pharma

APRIL 5, 2023

The group now has 358 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. Acetazolamide Tablets USP, 125 mg and 250 mg had annual sales of USD 16 mn in the United States (IQVIA MAT Dec.

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94

Big Molecule Watch

FEBRUARY 21, 2024

XOLAIR was initially approved by the FDA in 2003. Food and Drug Administration (FDA) approved XOLAIR (omalizumab) for the reduction of allergic reactions, including anaphylaxis, that may occur with accidental exposure to one or more foods in adult and pediatric patients aged 1 year and older with Immunoglobulin E (IgE)-mediated food allergy.

Biosimilars 57

Biosimilars 57

Express Pharma

APRIL 23, 2023

The group now has 365 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. (*as Icosapent Ethyl Capsules, 0.5 g and 1 g had annual sales of $1,316 million in the US (IQVIA MAT Feb. as of 31st December 2022) The post Zydus gets USFDA approval for Icosapent Ethyl Capsules, 0.5

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52

Express Pharma

APRIL 6, 2023

The group now has 359 approvals and has so far filed over 440* ANDAs since the commencement of the filing process in FY 2003-04. Carbidopa and Levodopa Tablets USP, 10 mg/100 mg, 25 mg/100 mg, and 25 mg/250 mg had annual sales of $75 million in the United States (IQVIA MAT Dec.

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79

Express Pharma

FEBRUARY 21, 2024

10 crore, as they are not based in states which enjoyed tax holidays from 2003 to 2017. The remaining 20 per cent would be unable to produce medicines for PMJK or most of the NLEM medicines because the production cost post implementation of the Revised Schedule M would be higher than the permitted MRPs.

Pharmaceutical Manufacturing 95

Pharmaceutical Manufacturing 95

Express Pharma

APRIL 2, 2024

Venkat Kamalakar Bundla, Managing Director, Garphi Biosciences T he Association is assisted by the ABLE Council of Presidents comprising all the past presidents of the Association that was founded in 2003. The Council is currently chaired by Dr P M Murali, Founder of Jananom.

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98

Express Pharma

FEBRUARY 1, 2024

10 crore, as they are not based in states which enjoyed tax holidays from 2003 to 2017. The remaining 20 per cent would be unable to produce medicines for PMJK or most of the NLEM medicines because the production cost post implementation of the Revised Schedule M would be higher than the permitted MRPs.

Pharmaceutical Manufacturing 96

Pharmaceutical Manufacturing 96

Express Pharma

JUNE 27, 2023

Announcing Gagandeep’s appointment, Mohammed Tawil, Regional Managing Director and Head of Human Pharma for India, Middle East, Turkey, and Africa at Boehringer Ingelheim said, “Since inception in 2003, our focus on improving patient outcomes in India remains steadfast.

Communication 89

Communication Pharmaceutical Companies Pharmaceutical Companies 89

RX Note

MAY 27, 2023

Choosing an Appropriate Probiotic Product for Your Patient: An Evidence-based Practical Guide, 2018 Clinical Uses of Probiotics, 2016 Probiotics: Choosing The Right One For Your Needs, 2003 Adverse Effects Adverse effects related to probiotic use may include Mild-to-moderate gastrointestinal complaints (e.g.

Community Pharmacies 52

Community Pharmacies 52

Pharmaceutical Technology

APRIL 11, 2023

Zydus, which currently has 360 approvals, has filed abbreviated new drug applications for more than 440 drugs since 2003-04. Zydus will manufacture the drug at its formulation facility in Moraiya, Ahmedabad, in the Indian state of Gujarat. The company stated that azithromycin tablets generated annual sales of $20m in the US.

Immunity 52

Immunity Immunization Vaccines 52

Express Pharma

APRIL 16, 2024

Between 2003 and 2009, the number of AIDS patients receiving treatment increased 18-fold, thanks to the accessibility of affordable medications. This impact extends beyond borders, with North America emerging as a key market and accounting for 34 per cent of India’s pharmaceutical exports, closely followed by Africa at 19 per cent.

Vaccines 103

Vaccines Generic Medicine Pharmaceutical Companies Pharmaceutical Companies 103

Eye on FDA

JANUARY 26, 2022

Eye on FDA maintains a database that contains the results of Warning and Untitled letters issued by OPDP going back through 2003. Warning Letters can be found performing a search here , while Untitled Letters are listed here. It includes 352 letters covering over 450 communications vehicles and over 1100 violations.

Communication 108

Communication Diabetes 108