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In some cases, reduced dosage or suspension of chemotherapy may be necessary to alleviate symptoms, leading to a clinical effect on the patient’s prognosis. After consultation with Japan’s Pharmaceuticals and Medical Devices Agency (PDMA) regarding potential clinical development, Asahi Kasei Pharma initiated the Phase III study.
It’s human instinct to want to destroy cancer as fast as possible. Cancer is this bug. To overcome that hurdle, Immuneering is testing an approach that slows cancer down rather than rushing to destroy it. And if you can do that, cancer becomes a chronic, manageable disease, like diabetes, cardiac disease or HIV.
Based on the FDA clearance, the company anticipates the commencement of Phase I clinical trials for ALX2004 in mid-2025. Its overexpression is associated with multiple tumour types, including colorectal carcinoma, breast cancer, non-small cell lung cancer and head and neck squamous cell carcinoma.
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At the 2025 Oncology Pharmacists Connect (OPC) meeting, Courtney Cavalieri, PharmD, BCOP, presented clinical trial findings in gastrointestinal (GI) cancers—including colon, gastric, pancreatic, and metastatic colorectalcancer—that highlight the expanding role of immunotherapy and targeted treatments.
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