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Using Tolerance Intervals for Evaluation of Uniformity of Dosage Units Data in Routine Batch Release

PharmaTech

This article introduces that the basic technique for tolerance interval is implemented using the conventional range 85–115% LC where the proposed range in the PF is not taken into account.

Dosage 98
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ebook: Twin-screw extrusion for pharmaceutical applications

European Pharmaceutical Review

Various dosage forms can be produced with a twin-screw extruder and corresponding downstream equipment. These include solid oral dosage forms such as buccal and transdermal, as well as new delivery systems like subcutaneous implants and transmucosal applications. Interested to know more? Register your details now!

Dosage 59
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Enhancing intestinal drug delivery with Quality by Design

European Pharmaceutical Review

the QbD method applied in the study is a robust tool for designing controlled-release dosage forms for oral administration such as colonic release formulations” According to the data, “batches with a 10 percent weight increase and varied HPMC viscosity grades and coating polymers [attained] ∼50 percent drug release at 24 [hours]”.

Dosage 98
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Episode 864: Why Did ISMP Remove the Do Not Crush List from Their Website?

Pharmacy Joe

Subscribe on iTunes , Android , or Stitcher If you navigate to the page on the website for the Institute for Safe Medication Practices that once hosted the document titled “Oral Dosage Forms That Should Not Be Crushed” you will instead find a notice that the list has been removed from the ISMP website.

Dosage 111
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Episode 575: Novel dosage forms that should not be crushed (but look like they can be)

Pharmacy Joe

In this episode, I’ll discuss novel dosage forms that should not be crushed but look like they can be. Episode 575: Novel dosage forms that should not be crushed (but look like they can be) Subscribe on iTunes , Android , or Stitcher Two relatively new dosage form technologies are nanocrystals and amorphous solid dispersions.

Dosage 40
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Roller Compaction: New Trends, Challenges and Solutions

PharmaTech

When developing a tablet or capsule formulation, three widely used technologies are often considered to produce solid dosage forms: direct compression, wet granulation and dry granulation (including roller compaction). This article discusses why roller compaction is a robust option.

Dosage 52
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Application of F Charts in Continued Process Verification of OSD Forms

PharmaTech

This article introduces a control chart technique using F statistic for continued process verification of oral solid dosage forms.

Dosage 52