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Scientists from the Institute of Cancer Research London, Imperial College London and the Netherlands Cancer Institute have researched a gene test which can select which advanced bowel cancer patients will respond the best to chemotherapy. read more
GSK has announced that the European Medicines Agency (EMA) has validated the company’s Type II Variation for a new indication for Jemperli (dostarlimab) alongside chemotherapy for the treatment of adult patients with mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) primary advanced or recurrent endometrial cancer.
Results of the pilot in 45 patients with non-small cell lung cancer (NSCLC) treated with Tecentriq with and without chemotherapy were published in 2020. The data showed that patients as well as physicians and nursing staff found the digital tool allowed “more efficient and focused communication” as well as time savings.
AstraZeneca has announced positive high-level results from an interim analysis of the DUO-O phase 3 trial assessing a combination of Lynparza (olaparib) and Imfinzi (durvalumab) alongside chemotherapy and bevacizumab. read more
It could be used for T-Cell Acute Lymphoblastic Leukaemia (T-ALL) treatment in patients for whom bone marrow transplantation and chemotherapy failed to work. The Spanish Association Against Cancer (AECC) provided funding for the new STAb therapy development.
Clinical evidence shows Bristol Myers Squibb’s nivolumab, with chemotherapy, could help extend the lives of patients with untreated HER2-negative, advanced or metastatic gastric, gastroesophageal junction, or oesophageal adenocarcinoma, if the tumours express PD-L1. read more.
Since the first ADC was approved by the EMA in 2012, they have generated a great deal of interest in the oncology field because of their potential to address many of the challenges of traditional chemotherapy options. Teams must also accept the variety of analytical procedures these regulatory agencies prefer.
AstraZeneca and MSD have announced that the MHRA has granted marketing authorisation for Lynparza (olaparib) in the UK, when used in combination with abiraterone and prednisone or prednisolone, to treat metastatic castration-resistant prostate cancer (mCRPC) in patients for whom chemotherapy is not recommended. read more
The antibody treatment was previously used as an additional layer of protection against the virus for those with compromised immune systems, such as those undergoing chemotherapy, or organ-transplant patients. read more
Peer teaching has been shown to improve learners’ communication skills, 2 confidence and interest in teaching, 3 and academic performance. Additionally, I developed a nonsterile compounding formulation for lidocaine popsicles to pair with the hazardous sterile chemotherapy for the oncology week.
The central hubs are located in larger communities, such as Fargo, N.D., These hubs offer surgical care, diagnostic procedures, radiation, chemotherapy and immunotherapy. The smaller, more rural community sites offer diagnostic imaging, chemotherapy, immunotherapy and some surgical care. and Duluth.
Traditionally, cancer patients are treated using “one size fits all” interventions like chemotherapy, radiotherapy and surgery. Visual communication. These tools not only make it easier to understand the service, but they can also help simplify communication and increase alignment between the many individuals engaged in the project.
This type of hearing loss can cause significant communication problems, particularly in noisy environments, and can affect an individual's personal and professional life. Medications: Some medications, such as antibiotics and chemotherapy drugs, can cause hearing loss as a side effect.
First and foremost, I always recommend having a good communication plan so that if an item goes on backorder, you can immediately alert your team. What is their communication or customer service like? What is your strategy for teaching somebody about finding a medication they can’t find but need to get for their practice?
The current standard of care for many cancers is cisplatin chemotherapy or platinum therapy. Additionally , loss of hearing at a young age is associated with impaired communication, cognitive impairment, poorer mental health and quality of life. The therapeutic landscape.
Designated as BG01-2202, this latest trial will be an open-label, randomised, controlled clinical study of UTD1 versus chemotherapy drug docetaxel. A Phase III study to evaluate UTD1 versus docetaxel in patients that have failed chemotherapy with a platinum-containing regimen is also currently underway in China. ORR, 81.0%
They state that newer drugs like monoclonal antibodies and kinase inhibitors may benefit from a drug optimisation approach due to their different dose escalation profiles, compared to the cytotoxic chemotherapy drugs. Please check your email to download the Report.
The journey that followed—filled with the courses of chemotherapy, surgeries, and radiation—tested me in ways I could never have imagined. The company’s mission to save lives by improving communication has become Nataliya’s personal guiding principle. Yet, throughout this tumultuous journey, I never once contemplated giving up.
Chemotherapy used to treat blood cancer results in increased intestinal permeability, making E. Subjects were dosed over seven days, and reportedly only experienced mild to moderate side effects with no withdrawals. coli a frequent cause of bloodstream infections that carries a 15-20% fatality rate.
In 2021, as part of the same Keynote-811 trial, the US Food and Drug Administration (FDA) granted accelerated approval to Keytruda for treating locally advanced unresectable or metastatic HER2-positive gastric or GEJ adenocarcinoma, in combination with trastuzumab and chemotherapy containing fluoropyrimidin and platinum.
In results presented at the ongoing American Society of Clinical Oncology (ASCO) Annual Meeting , Summit reported an overall response rate (ORR) of 67% in NSCLC patients with squamous histology treated with its lead drug ivonescimab plus chemotherapy. The treatment had an acceptable safety profile in combination with chemotherapy.
To close out the year, the FDA also approved on an accelerated basis Jazz Pharmaceuticalss ZIIHERA (zanidatamab-hrii), the first and only dual HER2-targeted bispecific antibody and chemotherapy-free treatment for patients living with biliary tract cancer; Merus N.V.s
Now, people living with particular types of lymphoma have individualised options beyond chemotherapy for the first time.”. We’ve learnt how best to communicate with people, their care partners and families, so they’re fully informed and able to take part in the conversation.
The company is focused on its planned first-in-human trial designed for assessing DNase, along with immune checkpoint inhibitors or chemotherapy. The collaboration will also support the development of XCART, a DNase-armoured personalised chimeric antigen receptor (CAR) T cell technology for the treatment of B-Cell lymphomas.
Current standard treatment involves chemotherapy and immunotherapy to shrink the tumour, before surgical removal. Uniquely, the Phase II/III trial added chemotherapy and oral olaparib pre-surgery. Patients had 48 hours between being given chemotherapy and olaparib. The study results were published in Nature Communications.
Chemotherapy agents: Chemotherapy agents can lead to constipation in a variety of ways such as slowing the movements of the intestinal tract or creating inflammation that disrupts digestive function. Chemotherapy-Induced Constipation and Diarrhea: Pathophysiology, Current and Emerging Treatments. 2020;12(1):205. Front Pharmacol.
government is testing a new way to prevent treatment disruptions for seven pediatric cancer drugs by improving communication between hospitals, nonprofits, and wholesalers. Low margins on cheap, generic drugs including chemotherapies have resulted in a fragile supply chain.
Go deeper with GlobalData Reports Chemotherapy in Pharmaceuticals: Platinum-based cancer drug composi. Sign up Share Copy Link Share on X Share on Linkedin Share on Facebook Go deeper with GlobalData Reports Chemotherapy in Pharmaceuticals: Platinum-based cancer drug composi. Sign up for our daily news round-up!
Go deeper with GlobalData Reports LOA and PTSR Model - Denosumab Biosimilar in Bone Metastasis Reports LOA and PTSR Model - Denosumab Biosimilar in Chemotherapy Effects Data Insights The gold standard of business intelligence. Find out more Sign up for our daily news round-up! Give your business an edge with our leading industry insights.
In June 2025, the European Commission authorised Takeda’s Adcetris (brentuximab vedotin), an antibody-drug conjugate, combined with chemotherapy for treating adults who are newly diagnosed with Stage IIb Hodgkin’s lymphoma with risk factors or at Stage III/IV. Sign up for our daily news round-up!
Dizal has received US Food and Drug Administration (FDA) approval for Zegfrovy (sunvozertinib) to treat adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations (exon20ins), following progression on or after receiving platinum-based chemotherapy.
Atara Biotherapeutics stated that the prior therapy for solid organ transplant patients includes chemotherapy unless chemotherapy is not suitable. The regulatory approval follows the Committee for Medicinal Products for Human Use (CHMP) of European Medicines Agency’s (EMA) positive opinion on Ebvallo in October.
Mok : Right now, we have a lot of chemotherapy being used, but there are many more novel treatments being studied, especially in earlier lines of treatment. Bispecifics are moving up in the lymphoma space, and these newer therapies may have some synergistic effects with chemotherapy. REFERENCES 1. Updated August 18, 2021.
The findings highlight that there remain communication gaps between oncology providers and patients and that opportunities exist for pharmacists to counsel newly diagnosed oncology patients on their fertility preservation options.
These job duties each require different skill sets, from writing and verbal communication to process development, technical aptitude, and deep clinical expertise. And we need people to work side by side with prescribers to manage complex drug interactions, drug toxicities, and the financial implications of treatment selection.
I think it’ll be chemotherapy—maybe their cells being given outpatient—and then, as we hit their hardest time or their highest risk for either febrile neutropenia or mucositis or even some of the toxicities from the chemotherapy, we have them inpatient until we feel comfortable, and then transition it so that it could be all outpatient.
CALD is associated with six major functional disabilities (MFDs) which severely compromise the ability to function independently, including loss of communication, need for tube feeding and complete loss of voluntary movement. The two patients from ALD-102 who have not reached month 24 have also shown no evidence of MFDs.
The ADC is already approved in the metastatic setting after chemotherapy or in the case of disease recurrence during or in six months after adjuvant chemotherapy. Baxter Biopharma Solutions has been contracted for the ADC’s parenteral manufacture and packaging. Please check your email to download the Report.
The first three years I was with Patterson Veterinary Supply, I was on the technology sales team, where I was responsible for selling practice management software and client communication tools that veterinary offices use daily. Epicur pretty much has everything taken care of one way or another.
Common treatment options for the condition include bladder removal surgery, chemotherapy and/or administration of the BCG vaccine in the bladder. Non-muscle invasive bladder cancer is characterised by cancer cells that remain only in the lining of the bladder. Please check your email to download the Report.
If a discrepancy is found, the pharmacy nurses will hold the shipment, and a clinical intervention will be communicated to the provider. The nurses complete a reassessment care plan prior to medications being shipped. During this time frame, the pharmacy documented 152 interventions.
Stéphane Thiroloix, CEO of AlgoTx Alongside erythromelalgia, the company is testing ATX01 in a Phase II study in chemotherapy-induced peripheral neuropathy (CIPN). Afterwards, the patients will receive a placebo or an active drug for three weeks before undergoing a three-week follow-up, adds Thiroloix.
Find out more J&J’s drug is an option for patients where medical or surgical treatment to lower testosterone levels has not worked, and in those who have BRCA 1/2 mutations – a subset of homologous recombination repair (HRR) mutations – in whom chemotherapy is not indicated. Give your business an edge with our leading industry insights.
Imfinzi is now approved to treat adult patients with resectable muscle-invasive bladder cancer (MIBC) in combination with chemotherapy drugs gemcitabine and cisplatin as neoadjuvant treatment, and as a monotherapy after bladder removal surgery. Imfinzi is a major revenue driver for AstraZeneca, generating around $4.7bn in sales in 2024.
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