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Will Novartis provide new oral option for chronic hives?

European Pharmaceutical Review

As a highly selective BTK inhibitor, remibrutinib “has the potential to be a first-in-class, oral treatment for people living with CSU whose symptoms are refractory despite use of antihistamines,” stated Dr Shreeram Aradhye, President of Global Drug Development and Chief Medical Officer at Novartis.

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Povetacicept by Alpine Immune Sciences for Systemic Lupus Erythematosus: Likelihood of Approval

Pharmaceutical Technology

Povetacicept is under clinical development by Alpine Immune Sciences and currently in Phase I for Systemic Lupus Erythematosus. According to GlobalData, Phase I drugs for Systemic Lupus Erythematosus have a 76% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. Buy the report here.

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Digital innovation drives vaccine development

pharmaphorum

The digital transformation is allowing pharmaceutical companies to expand their drug discovery capabilities and accelerate drug development. Partly as a result of these developments, vaccine innovation has grown by leaps and bounds in just the past year. Innovation at Pfizer.

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Data-crunching specialist CytoReason signs $110m Pfizer alliance

pharmaphorum

The two companies have been talking to each other since 2017 and formally working together since 2019, when Pfizer started using CytoReason’s biological models in research aimed at developing new drugs for immune-mediated diseases and cancer immunotherapies.

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Country focus: China & APAC’s growing medical needs bring opportunities and challenges

pharmaphorum

“But we are glad to see the situation for innovative drugs in Asian markets improving, especially in mainland China and South Korea, where policies, societies and regulations are actively promoting innovation. “At At the same time, lots of people with experience at multinational pharmaceutical companies have chosen to return home.

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Rare diseases, repurposing and the role of AI

pharmaphorum

The repurposing of drugs is becoming more common, especially in the field of rare diseases. Now, as part of lifecycle management, pharmaceutical companies are looking more closely at drugs they have on their shelves. In the past, repurposing has mostly been driven by academics looking for new possibilities in generics.

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MP-0310 by Molecular Partners for Cervical Cancer: Likelihood of Approval

Pharmaceutical Technology

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.