Thu.May 01, 2025

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Sedative ‘dex’ is replacing ‘tranq’ in illegal drug supply and causing excruciating withdrawal

STAT

The era of “tranq” may be ending. But tranq, as the powerful veterinary tranquilizer xylazine is known in the illicit drug supply, is being replaced at least in part by a dangerous new sedative: medetomidine. In the past year, the anesthetic has become an increasingly common element in the drug supply, with cities and states including Philadelphia, Pittsburgh, Chicago, and San Francisco reporting cases of medetomidine-involved overdoses.

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What will hub and spoke changes mean for independents?

The Pharmacist

From October, new legislation will enable pharmacies across separate legal entities to take advantage of hub and spoke dispensing, pending parliamentary approval. NHS England modelling has previously suggested that hub and spoke dispensing will increase 2% each year, freeing up workforce capacity to deliver more clinical services. But some sector leaders have raised concerns about […] The post What will hub and spoke changes mean for independents?

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STAT+: CVS Health’s Aetna to abandon Affordable Care Act insurance marketplaces, again

STAT

CVS Health will not sell its Aetna health plans in the Affordable Care Act’s individual marketplaces in 2026, marking the second time in the past decade that Aetna has given up on ACA coverage. CVS expects to lose up to $400 million this year in its ACA plans. The conglomerate set aside $448 million in the first quarter to cover medical claims from ACA members that won’t be covered by insurance premiums.

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Can real-world evidence bear some of the burden left by NIH cuts? This CEO sees an opportunity.

PharmaVoice

Turmoil at the NIH has led to handwringing among researchers and drugmakers who rely on public funding.

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Navigating Payroll Compliance: Future-Proofing Payroll in an Evolving Regulatory Landscape

Speaker: Jennifer Hill

Payroll compliance is a cornerstone of business success, yet for small and midsize businesses, it’s becoming increasingly challenging to navigate the ever-evolving landscape of federal, state, and local regulations. Mistakes can lead to costly penalties and operational disruptions, making it essential to adopt advanced solutions that ensure accuracy and efficiency.

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STAT+: Eli Lilly shares fall as competitor Novo notches coverage win for obesity drug

STAT

Shares of Eli Lilly dropped in pre-market trading Thursday, as competitor Novo Nordisk secured a major win on insurance coverage of its obesity drug and as Lilly reported first-quarter earnings that fell short of what investors wanted to see. CVS Caremark, the largest pharmacy benefit manager in the U.S., announced Thursday that starting in July, Novo’s weight loss treatment Wegovy will be the preferred GLP-1 medicine on its largest commercial formularies, likely making Wegovy more access

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Neogap chosen for Innovate Nordics 2025 Acceleration Programme

Pharmafile

Swedish biotech company Neogap Therapeutics has been chosen to join Innovate Nordics 2025 acceleration programme, a prestigious initiative designed to help Nordic growth companies expand into the US market. Organised by the Swedish-American Chamber of Commerce in New York (SACCNY) in partnership with EY, the programme provides selected companies with access to US investor networks, […] The post Neogap chosen for Innovate Nordics 2025 Acceleration Programme appeared first on Pharmafile.

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Tozaro appoints Jason Slingsby as CEO to lead commercial strategy in cell and gene therapy sector

Pharmafile

Tozaro, a technology provider specialising in cell and gene therapy (CGT) manufacturing, has appointed Jason Slingsby (pictured left) as its new chief executive officer (CEO). This supports Tozaros intent to accelerate the commercialisation of its Smart Polymer technology, which aims to enhance downstream viral vector manufacturing in CGT. Slingsby succeeds interim CEO Guy Leaver, who […] The post Tozaro appoints Jason Slingsby as CEO to lead commercial strategy in cell and gene therapy se

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Opinion: RFK Jr.’s synthetic dye bans miss a much bigger problem

STAT

As a professor of physiology, I study how scientific evidence gets translated, sometimes clumsily, from the lab to real life. Whether it’s scaling dietary supplements to humans or using biomimicry to mitigate sports concussion , my work often centers on the fine line between meaningful evidence and misleading extrapolation. That’s why I was immediately skeptical when the Food and Drug Administration announced its decision to ban synthetic food dyes like the controversial red dye No

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New $1.7b Novartis acquisition to advance novel microRNA inhibitor

European Pharmaceutical Review

Novartis AG has agreed to acquire the biopharmaceutical company Regulus Therapeutics Inc. This deal has potential total equity value of up to approximately $1.7 billion. It involves supporting advancement of Regulus’ lead product candidate, farabursen (RGLS 8429), a microRNA-17 (miR-17) inhibitor being developed to treat autosomal dominant polycystic kidney disease (ADPKD).

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Opinion: Why NIH’s policy on grants to universities with DEI programs is not cause for widespread alarm

STAT

The recent news that the NIH will require universities to certify their diversity programs comply with federal civil rights law created understandable anxiety in the academic community. The confusion is partly due to coverage that suggested NIH is terminating support for any universities that operate diversity, equity, and inclusion (DEI) programs. But reading the actual NIH notice carefully provides clarity — and perhaps some reassurance.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Leading the Charge in Equine Veterinary Care: An Innovative Treatment for Equine Gastric Disease

epicur

Veterinary professionals specializing in equine medicine have been treating equine gastric disease in horses for decades. This common and often debilitating condition has traditionally been treated orally. While traditional treatments are effective, the current treatment advice can be complex and time-consuming, making compliance more difficult for horse owners.

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STAT+: M&A is back, but nothing in biotech is neat or simple

STAT

This story first appeared in Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up  here  to get it delivered to their inbox. Biotech mood check: Happy Two acquisitions. Strong drug launches. FDA drug approvals. A rebounding XBI now 18% higher from its recent low.  All in, a very pleasant week so far.

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Nice recommends first AI medical device for skin cancer diagnosis in the NHS

Pharma Times

Approval marks milestone for AI use in frontline care

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CDC’s annual HIV report is missing crucial data

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning. It’s Liz here again, subbing for Theresa on this first day of May. Happy International Workers Day , Beltane , or Mayday to all who celebrate.

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Why Every Small Business Needs an HCM Solution: A Comprehensive Guide

Managing HR tasks like payroll, compliance, and employee data can overwhelm small businesses. That’s where a Human Capital Management (HCM) solution comes in. Our eBook, Why Every Small Business Needs an HCM Solution: A Comprehensive Guide , shows how an HCM system automates tedious processes, ensuring your business stays compliant and efficient. You’ll learn how to simplify payroll, eliminate costly errors, and empower your employees with self-service tools.

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AstraZeneca quietly exits neuroscience

BioPharma Dive

The company removed experimental drugs for Alzheimer’s, migraine and pain from its pipeline to focus more resources on “core therapeutic areas” and “high value” programs.

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US is planning $500m project on 'universal vaccines;' WSJ

pharmaphorum

The US will spend $500m to develop universal vaccines to protect against multiple virus variants, while changes to testing rules are raising concerns

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Clinigen announces executive appointments to drive growth and investor value

Pharmafile

Clinigen, the global pharmaceutical services group, has announced key leadership changes to accelerate its growth and strengthen its position in the expanding biopharma services market. Nihad Hasagic (pictured left) has been appointed senior vice president (SVP) of Clinigen Lifecycle Services (CLS), reporting directly to CEO Jerome Charton. CLS supports pharmaceutical and biotech clients across the […] The post Clinigen announces executive appointments to drive growth and investor value ap

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J&J scores FDA OK for immune drug touted as future blockbuster

PharmaVoice

The company has predicted that Imaavy — now approved for myasthenia gravis — could eventually earn more than $5 billion in annual sales at its peak.

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Best Practices to Streamline Compensation Management: A Foundation for Growth

Speaker: Joe Sharpe and James Carlson

Payroll optimization can be one of the most time-consuming and complex factors of small business management. Yet, organizations that crack the code on streamlining employee compensation often discover innovative avenues for growth. With the right strategies in place, outsourcing and streamlining payroll processes can result in substantial time and resource savings.

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CVS strikes Wegovy deal with Novo Nordisk

BioPharma Dive

The deal could expand access to its in-demand obesity drug at the expense of Eli Lilly, whose shares fell by double digits on Thursday.

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GSK sets up Nucala and Dupixent showdown in COPD

pharmaphorum

GSK has said new data leads it to believe Nucala will be "highly competitive" with rival biologic Dupixent in COPD if it gets approved by the FDA

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Siren, a gene therapy startup, tests unconventional alternative to venture funding

BioPharma Dive

Siren Biotechnology is trying to raise $5 million via the type of crowdfunding round that’s rarely used by young drugmakers.

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Leqembi dosing proposal for Alzheimer’s treatment validated by MHRA

Pharma Times

Application seeks reduced infusion frequency to support patient flexibility

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Enhance Healthcare Efficiency With Top Payroll & HCM Services

Running a healthcare facility requires precision and care, not just for patients but also for your staff. Our guide, "A Buyer’s Guide to Payroll & HCM Services," helps healthcare providers choose the best provider. Efficient payroll management ensures timely, accurate payments, critical for maintaining staff morale and trust. Compliance support helps navigate complex healthcare regulations and avoid costly fines.

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FDA approves J&J’s Imaavy for generalised myasthenia gravis

Pharmaceutical Technology

J&J's Imaavy (nipocalimab-aahu) has received US Food and Drug Administration (FDA) approval for treating generalised myasthenia gravis.

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New analysis: Fewer treatments and cures under the IRA’s pill penalty

PhRMA

Patients in the U.S. will soon be left with fewer new, affordable and convenient treatments, if Congress fails to fix a harmful provision in the Inflation Reduction Act (IRA) referred to as the “pill penalty.

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Madrigal’s MASH drug sales again top Wall Street projections

BioPharma Dive

Rezdiffra sales reached $137 million for the quarter, beating consensus analyst estimates by more than $20 million and continuing a faster-than-expected drug launch.

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When hospitals have free rein to mark up drug prices, who pays the price?

PhRMA

The 340B hospital markup program continues to skyrocket every year. Yet there is little to no evidence that this immense growth is benefiting the uninsured and low-income patients that the program was designed to serve. If the money isn’t going to help patients, where is it going?

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Skin Analytics' dermatology AI backed for NHS use

pharmaphorum

An AI-powered tool for triaging patients with suspicious skin lesions, developed by Skin Analytics, will be used by the NHS to reduce waiting times

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A candidate drug dismantles a metabolic barrier to anti-tumor immunity

World Pharma News

A Ludwig Cancer Research study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune responses. Harnessing that insight, researchers led by Ludwig Lausanne's Ping-Chih Ho and Yi-Ru Yu - along with Sheue-Fen Tzeng and Chin-Hsien Tsai, former post-docs in the Ho lab who now lead their own labs at Taipei Medical University in Taiwan - have developed a humanized antibody to dismantle that barrier as a potential can

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J&J's 'Swiss army knife' drug gets first FDA approval

pharmaphorum

Johnson & Johnson has its first regulatory approval for FcRn blocker Imaavy, getting a green light in the US for generalised myasthenia gravis (gMG)

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Arvinas, Entrada cut staff; Merck builds US hub for Keytruda

BioPharma Dive

Arvinas is laying off about a third of its workforce, while Entrada is focusing more on Duchenne research. Elsewhere, Biogen talked down tariff impacts and Merck earmarked $1 billion for a biologics production plant.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.