March, 2024

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GLP-1 generics would be dramatically cheaper than U.S. price of Ozempic, study shows, but still profitable

STAT

Diabetes drugs are too expensive in the U.S., and insulin is infamously six to 13 times more expensive here than in comparable high-income countries. And blockbuster GLP-1 drugs, too, could be a lot less expensive, according to an investigation published this week in JAMA Network Open, with a simple change: robust generic competition. The study, led by Melissa Barber, a Yale postdoctoral fellow, and conducted in collaboration with Doctors Without Borders, a nonprofit medical organization working

Diabetes 363
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SAEM Clinical Images Series: Purple Finger

ALiEM - Pharm Pearls

A 30-year-old female with a past medical history of Crohn’s Disease presented to the ED for evaluation of an acutely bruised right 4th finger. She stated she was typing on a computer keyboard approximately 10 minutes prior to presentation and she noticed a sudden popping sensation at the base of her right ring finger. After the popping sensation, she noticed a cool sensation of the finger and numbness to the entire finger.

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After Amylyx drug failure, what’s next for ALS?

PharmaVoice

The company’s combo treatment Relyvrio was approved in 2022, but after failing a phase 3 trial, may be pulled from the market.

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An open letter: Concerns on electoral bonds and pharma industry

Express Pharma

Chandru Chawla, a pharma veteran writes an open letter to those CEOs of Pharmaceutical companies who have NOT purchased Electoral Bonds and have NOT made political donations through other means Dear Pharma CEO who did NOT make political donations Compliments from an ordinary soon-to-be senior citizen and a consumer of medicines. Recently, ordinary folks like me have been bombarded with this alleged scam being referred to as Chanda Do Dhanda Lo.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Pharmacist in practice: working with community nurses to support heart failure patients

The Pharmacist

Senior clinical pharmacist Brendon Jiang is vice-chair of the Royal Pharmaceutical Society (RPS) English Pharmacy Board and leads North Oxfordshire Rural Alliance (NORA) primary care network (PCN), a large team of eight pharmacy staff working across the Cotswolds. Here he tells The Pharmacist how PCN pharmacists are working with community heart failure nurses to upskill, […] The post Pharmacist in practice: working with community nurses to support heart failure patients appeared first on T

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Cannabinoids show promise in acute migraine clinical trial

pharmaphorum

Inhaled cannabinoids have been shown to perform better than placebo in providing pain relief for people suffering from acute migraine in a clinical trial

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How Women of the CPA are Accelerating Healthcare Progress Across the Commonwealth

Commonwealth Pharmacists Association

International Women’s Day 2024: Invest in women—accelerate progress Leading with Impact: How Women of the CPA are Accelerating Healthcare Progress Across the Commonwealth At the Commonwealth Pharmacists Association, we believe that investing in women leaders is a catalyst for transformative change in healthcare worldwide. Our leadership team, predominantly composed of women, exemplifies this commitment.

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Amylyx ALS drug fails crucial study, putting company’s future in doubt

BioPharma Dive

The results have led Amylyx to pause promotion of Relyvrio and potentially pull it from the market in the coming weeks, a major blow to the company and ALS patients.

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When £17m isn’t enough: FTSE firms plead to pay bosses millions more

The Guardian - Pharmaceutical Industry

Confronted by the huge salaries on offer in the US, London boardrooms are lobbying to be allowed to make their own bosses even wealthier There was a sharp intake of breath last month when the pharmaceuticals group AstraZeneca cemented chief executive Pascal Soriot’s position as the best-paid FTSE 100 boss with a £17m pay package , up from £15.3m a year earlier.

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Pharmacy closures 'could double' without action, contractors warn

The Pharmacist

Pharmacy closures are a 'worry' for patients and could 'double' if action is not taken to prevent them, community pharmacy representatives have said as they gathered outside the Houses of Parliament yesterday before meeting with MPs. Complete with a giant map to illustrate the scale of the closures in regions across England, the event marked […] The post Pharmacy closures 'could double' without action, contractors warn appeared first on The Pharmacist.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Nanoscope preps filing for retinitis pigmentosa gene therapy

pharmaphorum

Nanoscope Therapeutics is on the brink of filing for FDA approval of what could be the first gene therapy for incurable eye disease retinitis pigmentosa (RP) that can be used regardless of underlying genetic mutations.

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Why researchers think human milk could repair the gut microbiome and reduce infections

STAT

For babies who are breastfed, their first source of sustenance is filled with proteins, sugars, hormones, vitamins, and minerals — just the right amount of nutrients for an infant. That milk could also lower the risk of asthma , diabetes, and allergies. And it could make low-birth-weight, preterm babies up to 10 times less likely to develop necrotizing enterocolitis , a common intestinal disorder.

Diabetes 362
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Guest Blog: Kidney Month Marks 31 Days of Action to Equip and Empower People to Prioritize their Kidney Health and Fight Kidney Disease

Putting Patients First Blog

Guest Blog: Kidney Month Marks 31 Days of Action to Equip and Empower People to Prioritize their Kidney Health and Fight Kidney Disease March 18, 2024 LaVarne A. Burton, President and CEO, American Kidney Fund March is Kidney Month , a month in which the American Kidney Fund (AKF) marks 31 days of action that are focused on equipping and empowering people with the tools and knowledge they need to prioritize their kidney health and fight kidney disease.

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Madrigal wins FDA approval of first drug for MASH

BioPharma Dive

Rezdiffra’s clearance is a turning point in the fight against the liver disease. But its sales potential is unclear, and competition could emerge from popular weight loss drugs.

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Pain is reduced by almost half with cannabis-based medicines – report finds

Outsourcing Pharma

On March 7, Celadon Pharmaceuticals plc, a leading UK-based pharmaceutical company specializing in cannabis-based medicines, unveiled promising findings from an early economic analysis of its chronic pain clinical trial, dubbed CANPAIN.

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Women in pharmacy: overcoming imposter syndrome and inspiring inclusion

The Pharmacist

This International Women’s Day focuses on the theme ‘Inspire Inclusion’: championing diversity in leadership and highlighting the experiences of women from all walks of life. The Pharmacist spoke to four female pharmacy leaders to hear how their different experiences of being women and pharmacists have influenced their work and leadership within the profession.

Hospitals 132
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AI in Drug Discovery: Day One

pharmaphorum

There is no denying that artificial intelligence (AI) has captured the imagination of innovators working across the pharmaceutical sector. The drug discovery space is no different, with myriad applications promising to revolutionise the way that researchers and sponsors approach identifying and progressing new drug candidates.

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STAT+: Why the world’s most expensive drug might not be all that overpriced

STAT

The staff of the Institute for Clinical and Economic Review, or ICER, are known as the nerds of the drug industry: bespectacled killjoys who emerge a few times a year to scold drugmakers for pricing their latest cancer or MS advance far beyond reason. But last year, its staff sat down and concluded a forthcoming treatment was worth up to $3.9 million — more than any medicine in history, more than a 45-year supply of Humira, the autoimmune drug often held up as an emblem of America’

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PulmCrit Wee: Propofol induced eyelid opening apraxia – the struggle is real

EMCrit Project

Eyelid opening apraxia refers to a specific inability to open the eyelids. This may result from non-dominant hemispheric strokes. On superficial examination it will mimic unconsciousness, but upon further examination the patient is awake and able to respond to stimuli with their extremities. I've seen a similar phenomena of eyelid opening apraxia a few times […] EMCrit Project by Josh Farkas.

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Biotech stock fundings headed for best quarter in 3 years, Jefferies says

BioPharma Dive

Publicly traded companies raised nearly $10 billion in follow-on stock offerings in January and February, a financing surge that’s driving a “sector recovery,” the investment bank said.

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Swedish researchers develop new AI computer model to detect lymphatic cancer

Pharma Times

In the study, the Lymphoma Artificial Reader System accurately detected 90% of lymphatic cancers

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Mahendra Patel: 'Let’s have the difficult conversations'

The Pharmacist

Working together with other healthcare professions will be crucial to embedding community pharmacy within the future of the NHS, pharmacist and academic Dr Mahendra Patel has told The Pharmacist. And the new cross-sector Independent Pharmacy Professional Leadership Advisory Board is an opportunity for community pharmacy to have an ‘equal voice’ in ‘difficult conversations’ that set […] The post Mahendra Patel: 'Let’s have the difficult conversations' appeared first on The Pharmac

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Why gut bacteria is the next frontier in medicine

pharmaphorum

Discover why gut bacteria are considered the next frontier in medicine in this informative article. Learn about the importance of the microbiome, its impact on health, and how it relates to conditions like Clostridiales difficile.

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STAT+: Steward Health Care has deal to sell doctor network to UnitedHealth

STAT

Troubled hospital operator Steward Health Care, grappling with a financial crisis that’s engulfed its eight Massachusetts hospitals, has moved to shore up its finances by striking a deal to sell its nationwide physician network to insurance giant UnitedHealth’s Optum Care unit. The proposed sale of the doctors group, called Stewardship Health, is part of Steward’s plan to bolster its national system of 33 hospitals after the Dallas-based company last year fell behind in payi

Hospitals 363
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Akums introduces Hydroxyurea oral suspension for sickle cell disease

Pharmaceutical Technology

Akums Drugs and Pharmaceuticals has introduced Hydroxyurea oral suspension, a room temperature-stable drug for treating sickle cell disease.

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Madrigal, FDA approval in hand, outlines plan to sell MASH drug

BioPharma Dive

The company expects initial uptake of Rezdiffra, which costs $47,400 per year, to be slow as doctors and insurers establish the protocols needed to find patients eligible for treatment.

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FDA Approves Semaglutide for New Indication Involving Cardiovascular Disease

Pharmacy Times

Semaglutide (Wegovy; Novo Nordisk) reduces the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and either obesity or overweight when combined with the standard-of-care.

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Five Things To Know: How To Use Artificial Intelligence To Be A Better Clinical Pharmacist

ID Stewardship

In this article a clinical pharmacist with experience and knowledge about using artificial intelligence describes how it can be used to be a better clinical pharmacist. Authored By: Steven Smoke, Pharm.D., BCIDP, BCPT Article Posted 18 March 2024 In healthcare’s evolving landscape, artificial intelligence (AI) promises to redefine pharmacy. AI chatbots like ChatGPT and Gemini offer not-so-subtle hints at AI’s transformative potential.

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Employee experience in healthcare: The importance of EX for patient experience

pharmaphorum

Understanding the employee experience in healthcare is essential for improving the patient experience. Learn more about the importance of employee experience in healthcare and how it impacts patient care.

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Disparities in donor acceptance rates point to need for more equitable heart transplant care

STAT

When a patient is going through end-stage heart failure, the best treatment is to get a heart transplant. The basic steps are familiar: First a patient gets on the waiting list, and then the wait begins for the offers. In recent years, access to donor hearts has gone up thanks to a change in heart allocation policy, but there are still gender- and race-based disparities in the acceptance rate of a donor heart offer by transplant teams, according to new research published Monday in the Journal of

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The growing uses of medicinal cannabis

Pharmaceutical Technology

Demand for medicinal cannabis is increasing globally to treat a range of illnesses and conditions.

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After surprise trial failure, ALS doctors brace for one less treatment option

BioPharma Dive

Physicians are preparing for tough conversations with patients on Amylyx Pharmaceuticals’ drug, Relyvrio, while holding out hope it still may help some with the disease.

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Study: Researchers Identify 25 Air Pollutants Associated With Asthma Symptoms

Pharmacy Times

Investigators found that 1,1,1 trichloroethane; 2-nitropropane; and 2,4,6 trichlorophenol were significantly associated with asthma symptoms for 3 exposure periods.

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STAT+: Some nonprofit hospitals spend less on charity care than they receive in tax breaks, new analysis shows

STAT

A new study of hospitals’ charity care spending suggests nonprofit hospitals really aren’t that different from their for-profit counterparts. One major benefit of being a nonprofit hospital is receiving tax exemptions on property taxes, income taxes, and sales taxes. Experts told STAT that implies a “social contract” with taxpayers, where these hospitals will help take care of the most vulnerable.

Hospitals 362
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STAT+: During the pandemic, were great vaccines bad business? A company-by-company review

STAT

It’s been four years since Covid-19 emerged, igniting a pandemic that killed millions of people and brought the world to its knees. A key factor in taming the pandemic was the creation of effective vaccines , which have saved millions of lives. You’d think developing a successful vaccine would be an unmitigated win, from a financial perspective.

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