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Episode 547: How to predict the pharmacotherapy needs of your patient and team during an inpatient medical emergency

Pharmacy Joe

In this episode, I’ll discuss how to predict the pharmacotherapy needs of your patient and team during an inpatient medical emergency. This is when you do regular pharmacist things like drawing up and labeling medications, and calculating doses. This work is valuable because it frees a nurse up to be hands-on with a patient.

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Episode 863: Does This Randomized Trial Settle the Increased AKI from Piperacillin-Tazobactam Question?

Pharmacy Joe

The ACORN randomized trial sought to compare rates of AKI and neurotoxicity in patients hospitalized with acute infection who were randomized 1:1 in an open-label fashion to receive either piperacillin-tazobactam or cefepime for gram-negative coverage. However, other studies have examined a link between increased neurotoxicity with cefepime.

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Episode 863: Does This Randomized Trial Settle the Increased AKI from Piperacillin-Tazobactam Question?

Pharmacy Joe

The ACORN randomized trial sought to compare rates of AKI and neurotoxicity in patients hospitalized with acute infection who were randomized 1:1 in an open-label fashion to receive either piperacillin-tazobactam or cefepime for gram-negative coverage. However, other studies have examined a link between increased neurotoxicity with cefepime.

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Episode 561: Rivaroxaban, mitral valves, and atrial fibrillation

Pharmacy Joe

To improve the data available in this patient population, investigators in Brazil completed a multicenter, randomized, open-label, noninferiority trial with 1000 patients comparing rivaroxaban with warfarin for patients with atrial fibrillation and a bioprosthetic mitral valve.

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Episode 741: Is it safe to use early antibiotic discontinuation in hematology patients with fever of unknown origin during chemotherapy-induced neutropenia?

Pharmacy Joe

Recently published in Lancet was a non-inferiority, open-label, multicentre, randomized trial that sought to clarify the safety of early antibiotic discontinuation in hematology patients with fever of unknown origin during chemotherapy-induced neutropenia.

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Episode 869: Three Recent Studies About Haloperidol and ICU Delirium

Pharmacy Joe

Adverse event rates were similar between groups. Secondary outcome measures were numerically favorable for haloperidol including the need for open-label haloperidol or other antipsychotics, and self-extubation or invasive device removal. However none of these secondary outcomes reached statistical significance.

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Episode 869: Three Recent Studies About Haloperidol and ICU Delirium

Pharmacy Joe

Adverse event rates were similar between groups. Secondary outcome measures were numerically favorable for haloperidol including the need for open-label haloperidol or other antipsychotics, and self-extubation or invasive device removal. However none of these secondary outcomes reached statistical significance.