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Mesoblast pummelled as Novartis exits COVID deal

pharmaphorum

In COVID-19, the drug was being tested in patients with acute respiratory distress (ARDS), which like GvHD is caused by over-stimulation of inflammatory cytokines, which causes the immune system to attack the patient’s own body. It has made cumulative loses of almost $650 million since being founded in 2004.

Immunity 101
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Reconfiguring COVID and influenza vaccines for long-term effectiveness

pharmaphorum

When exposed to a virus, one’s immune system develops antibodies in response to foreign antigens, with or without a vaccine. However, a vaccine trains the immune system to recognise that familiar virus and kill it more rapidly. Osivax’s technology, oligoDOM, trains the T-cell immune response to recognise the nucleoprotein.

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Sugemalimab plus chemo boosts lung cancer survival, trial reveals

pharmaphorum

Some cancer cells contain large amounts of PD-L1, which helps them to evade the body’s immune system. Lung cancer prevalence rates have risen by 23% since 2004, notes the BLF: “The earlier part of this trend may have been affected by changes in the way data were collated and incentivised.

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The Febrile Infant: Incorporating the 2021 American Academy of Pediatrics guidelines

ALiEM - Pharm Pearls

2004 Mar 10;291(10):1261-2. Febrile infants 29-60 days old may be sent home after a negative workup with close follow-up. References: Roberts KB. Young, febrile infants: a 30-year odyssey ends where it started. PMID: 15010450. Biondi EA, Lee B, Ralston SL, et al.

Hospitals 360
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The future of targeted alpha therapy development and manufacture

European Pharmaceutical Review

Firstly, alpha particles exhibit greater biological effectiveness by inducing irreparable DNA double-strand breaks, minimising the risk of resistance or immune escape in tumour cells. He then worked at BCG from 2004 to 2011, where he developed expertise in the energy, engineering, and high-tech sectors.

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Strategies to Overcome Anxiety with Hashimoto’s

The Thyroid Pharmacist

A study in 2004 found an association between the presence of a mood or anxiety disorder, and the presence of anti-TPO antibodies. [1] In the early stages of Hashimoto’s, the thyroid is under attack by the immune system. Thyroid antibodies are a marker that lets us know that the immune system is destroying thyroid tissue.

Immunity 105
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Top 20 Radiopharma Companies Based on Market Cap

PharmaShots

Market Cap: $8.46M Founded Year: 2004 Total Employees: ~4 Headquarters: Texas, United States Stock Exchange: OTCMKTS QSam Biosciences is a clinical-stage biotech company focused on developing and commercializing targeted therapeutic radiopharmaceutical products for treating cancer and related diseases.

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