article thumbnail

Guest Post: Legislation Needed to Improve Access to Vital Treatment for Medicare Rare Disease Patients

Putting Patients First Blog

While there are no cures for CIDP or MMN, there are fortunately some effective therapies, most notably immune globulin (IG), which replaces the malfunctioning antibodies with healthy antibody proteins isolated from donated human plasma. Adrian Smith (R-NE) and John Garamendi (D-NC). more times each year than non-enrollees and were 12.5%

article thumbnail

SAEM Clinical Images Series: Rapidly Spreading Rash

ALiEM - Pharm Pearls

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): An Interplay among Drugs, Viruses, and Immune System. 2013 Jun;6(6):31-7. Int J Mol Sci. 2017 Jun 9;18(6):1243. doi: 10.3390/ijms18061243. PMID: 28598363; PMCID: PMC5486066. Choudhary S, McLeod M, Torchia D, Romanelli P. J Clin Aesthet Dermatol.

Immunity 177
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

GSK Sues Pfizer for Patent Infringement over RSV Vaccine

Big Molecule Watch

Food and Drug administration in May 2023 for use in adults over age 60, becoming the world’s first approved RSV immunizations for adults. According to the complaint, AVREXY and ABRYSVO were approved by the U.S. GSK describes the four asserted patents, U.S. Patent Nos.

article thumbnail

BioNTech to set up mRNA manufacturing site in Singapore

pharmaphorum

Together the pair had managed to find a way to get the human body to accept strands of mRNA without an immune reaction, by tinkering with the chemical make-up of the molecule. BioNTech is run by husband-and-wife team Ugur Sahin and Ozlem Tureci and in 2013 hired the expertise of Kariko.

Vaccines 129
article thumbnail

mRNA researchers awarded 2023 Nobel Prize

European Pharmaceutical Review

The discoveries by the two Nobel Laureates have revolutionised science’s understanding of how messenger RNA (mRNA) interacts with the immune system. Key developments: mRNA vaccines and therapeutics Katalin Karikó In 1989, Katalin Karikó was appointed Assistant Professor at the University of Pennsylvania, where she stayed until 2013.

Vaccines 103
article thumbnail

Moderna Litigation Against BioNTech and Pfizer Stayed Pending IPR

Big Molecule Watch

Pfizer and BioNTech’s IPR petitions allege that the ‘127 and ‘600 patents are directed to “the use of mRNAs encoding any spike protein or spike protein subunit of any betacoronavirus, formulated in a broadly claimed lipid delivery system, to induce an immune response.”

article thumbnail

Chickenpox

RX Note

Use varicella zoster immune globulin (VariZIG) as postexposure prophylaxis in immunocompromised patients, pregnant women, premature infants, and neonates born to mothers with evidence of infection if able to give within 96 hours of exposure to varicella (preferably within 48 hours). Give antiviral medication (e.g.