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Kyowa Kirin gets approval in Japan for calcimimetics agent Orkedia Tablets 4mg

Pharmaceutical Business Review

Since the launch in May 2018, its low dosage forms, Orkedia Tablets 1mg and Orkedia Tablets 2mg have helped many patients in the country, stated the company. In March 2018, Orkedia was granted approval in Japan to treat secondary hyperparathyroidism in dialysis patients and was later launched in the country in May 2018.

Dosage 52
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ACMT Toxicology Visual Pearl: Who Doesn’t Like a Nice Rosé?

ALiEM - Pharm Pearls

[1,2] Severe symptoms such as hypovolemia, shock, metabolic acidosis Persistent and severe GI symptoms Lethargy or toxic appearance Serum iron level greater than 500 mcg/dL What is the dosage of deferoxamine for iron toxicity? [1] 22 Aug 2018. 1] Initial dosing starts at 5 mg/kg/hr intravenously. 2000 Jun;59(6):1233-50.

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Rx Guide

RX Note

In Jan 2018, I decided to compiled the notes that I once tabulated into a short series of PDFs. Working life is not as rosy as I once thought. After 8 hours of work, I often found I am "dead" at the end of day. However, at the same time, I have learned so much in this journey. Please refer to more reliable resources whenever in doubt.

Dosage 40
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Securing every dose with an edible security technology for safe medicines

European Pharmaceutical Review

On- or in-dose authentication means that a security measure or anticounterfeit feature is integrated with the dosage form itself, offering product verification and traceability embedded into each medicine, rather than on the secondary package” WHO estimates that >50 percent of the drugs for sale on the internet are fake. References.

Dosage 86
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Therapeutic Drug Monitoring (TDM)

RX Note

If the drug level is found to be below or above the range, it will serve as a guide for dosage adjustment. Objectives For simplistic purpose, there are 3 different occasions where we choose to do a TDM: To ensure the narrow therapeutic window drug level is within therapeutic range.

Dosage 52
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Recommended Medical Reference

RX Note

Regardless, this post is solely created as a collection of recommended reference.

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Statins

RX Note

NOTE: The FDA recommends rosuvastatin dosage reductions in Asian patients to maximum 20 mg daily because pharmacokinetic studies have demonstrated an approximate two-fold increase in median exposure to rosuvastatin in Asian subjects when compared to Caucasian controls. Stopping Statins?

Dosage 52