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Texas dairy farm worker’s case may be first where bird flu virus spread from mammal to human, scientists say

STAT

A new report on the first human bird flu case tied to the outbreak in cows in the United States suggests that the Texas man may be the first detected case of the H5N1 virus transmitting from a mammal to a person. Nearly 900 people in 23 countries have been infected with the H5N1 bird flu virus since it started spreading from Southeast Asia in late 2003.

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Takeover target? Activist investor believes Novavax tech would be in ‘better hands’ with Big Pharma

PharmaVoice

With its next earnings report looming, pushback from an investor is adding pressure on Novavax to boost performance.

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As AI proliferates in pharma, regulators look to catch up in clinical trials

PharmaVoice

The FDA’s newly launched Center for Clinical Trial Innovation potentially opens the door for more efficient and expanded AI use, but leaves pharmas wanting more guidance.

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AstraZeneca admits Covid-19 vaccine may cause blood clots in “very rare” cases

Pharmaceutical Technology

AstraZeneca has maintained that while the vaccine may, in “very rare” cases, cause TTS, the casual mechanism for this effect remains unknown.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Amgen shares soar as executives outline obesity drug push

BioPharma Dive

The company said data for its Wegovy competitor was promising enough to move the drug into late-stage testing, triggering a stock jump that added billions to Amgen’s market value.

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Have your say on PCN pharmacy and you could win a £200 voucher

The Pharmacist

Together with our sister publications, The Pharmacist has launched a survey to hear what pharmacists think about the last five years of change in primary care. The State of Primary Care Survey asks how the changes to the NHS — the launch of primary care networks (PCNs) in 2019 and the shift to integrated care systems (ICSs) in 2022 […] The post Have your say on PCN pharmacy and you could win a £200 voucher appeared first on The Pharmacist.

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Angle signs AstraZeneca deal to develop prostate cancer assay

Pharmaceutical Technology

UK liquid biopsy company, Angle, has agreed a supplier agreement with AstraZeneca to develop a Parsotix-based Androgen Receptor (AR) assay for use in prostate cancer studies.

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GSK raises forecasts on strong vaccine, HIV drug sales

BioPharma Dive

Sales of the shingles vaccine Shingrix and the RSV shot Arexvy helped fuel quarterly revenue totals that surpassed analyst expectations, though the company warned momentum could slow in the months ahead.

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Walmart retreats from healthcare, closing clinics across US

pharmaphorum

For the last few years, Walmart has been promising to disrupt the US healthcare sector with a national network of clinics providing low-cost care and telehealth services. Now, it is reining back on those plans.

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Scientists spot an orangutan using a plant to treat his own wound in the wild

STAT

When male Sumatran orangutans let out a long call, they’re usually trying to grab female attention. But the sounds — a booming blend of roars and grunts — can end up attracting unwanted attention from other males, too. Things can get tense. Which is likely how Rakus, an adult male orangutan frequently seen in Gunung Leuser National Park in South Aceh, Indonesia, acquired a face wound in June 2022.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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‘Our culture is dying’: vulture shortage threatens Zoroastrian burial rites

The Guardian - Pharmaceutical Industry

Inadvertent poisoning of scavengers across Indian subcontinent is forcing some communities to give up ancient custom Traditional Zoroastrian burial rites are becoming increasingly impossible to perform because of the precipitous decline of vultures in India, Iran and Pakistan. For millennia, Parsi communities have traditionally disposed of their dead in structures called dakhma, or “towers of silence”.

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Pharmacy First: Top tips for managing shingles

The Pharmacist

CLINICAL UPDATE The Pharmacy First service in England enables pharmacists to diagnose and treat seven specific conditions, with the aim of reducing current pressures on general practice. This series of guides assumes that pharmacists are familiar with the clinical pathways and requirements for Pharmacy First. The articles explore some key aspects of each service to […] The post Pharmacy First: Top tips for managing shingles appeared first on The Pharmacist.

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Enlaza gets JP Morgan, Regeneron backing for covalent biologics

BioPharma Dive

The funds will help the cancer-focused startup Enlaza bring “several development candidates” towards human testing in the next few years, its CEO said.

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ESCMID 2024: Using AI in infection prevention and control

Pharmaceutical Technology

Artificial intelligence tools can be used for infection control through facial recognition systems designed to identify proper face mask use within hospitals.

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Tracking bird flu virus changes in cows is stymied by missing data, scientists say

STAT

Another upload of genetic sequence data from the H5N1 bird flu outbreak in dairy cattle has exacerbated the scientific community’s frustration with the U.S. Department of Agriculture after the agency again failed to include basic information needed to track how the virus is changing as it spreads. Like a large tranche of sequences that the USDA uploaded to a public database on April 21, this week’s data dump did not include information about where and when the sequenced samples wer

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SSRIs In Pregnancy

Med Ed 101

Depression is one of the top three health disorders in adults ages 18-34 with approximately 21.3% of these adults having depression. This means that many women suffer from depression during their peak childbearing years and will begin medication to treat it. Uncontrolled depression or anxiety may lead to issues in pregnancy. Thus, there is always […] The post SSRIs In Pregnancy appeared first on Med Ed 101.

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Jacobio plans bid for China’s KRAS market with safety edge

pharmaphorum

China's Jacobio Pharma is preparing to file its KRAS inhibitor glecirasib for approval, saying it could offer a safety advantage over current drugs in the class

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Reunion raises over $100M to build a better psychedelic drug

BioPharma Dive

The funding will help Reunion pay for a mid-stage study testing its most advanced medicine — essentially a synthetic version of the hallucinogenic psilocin — in women with postpartum depression.

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MHRA publishes strategy on AI regulation

European Pharmaceutical Review

The Medicines and Healthcare products Regulatory Agency (MHRA) has published a policy paper on its strategic approach to artificial intelligence (AI). It summarises the MHRA’s view on the UK government’s white paper on AI regulation published in 2023. Following publication of this white paper, the government requested that the MHRA outline the steps the agency is working on in relation to its expectations.

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Pasteurization inactivates H5N1 bird flu in milk, new FDA and academic studies confirm

STAT

Extensive testing of pasteurized commercially purchased milk and other dairy products from 38 states has found no evidence of live H5N1 bird flu virus, Food and Drug Administration officials said at a press briefing Wednesday. The results confirmed findings of earlier testing of a more limited number of samples and add weight to the FDA’s conclusion that pasteurized milk products are safe for consumption despite a widespread outbreak of cows infected with H5N1.

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The Relationship Between Cold Chain Logistics and Cell & Gene Therapies

Pharmaceutical Commerce

A one-on-one with Thermo Fisher’s Wilfredo Marin, who dives into the value of ultra-low temperature storage, the need for flexibility in the cold chain logistics space, and more.

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Merck, Huma alliance bears fruit with UK bladder cancer app

pharmaphorum

A partnership between Huma Therapeutics and Merck KGaA to develop digital support tools for cancer patients has borne fruit with the launch of a bladder cancer app in the UK

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Lilly hikes revenue forecast by $2B as GLP-1 drug sales climb

BioPharma Dive

Supply continues to be tight, however, and the company anticipates further sales growth to be limited by how quickly it can bring on additional production capacity.

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What is the future of biologic medicines?

European Pharmaceutical Review

Recent developments in the biologic therapies sector include the authorisation of Pyzchiva ® (biosimilar ustekinumab) by the European Commission, and promising 12-month data for Roche’s subcutaneous injection of OCREVUS ® (ocrelizumab) for relapsing or primary progressive multiple sclerosis. The biologics market is expected to continue its fast growth despite the slowdown in funding observed in the past year.

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After private equity firms gobbled up wheelchair makers, users pay the price in long repair times

STAT

When Maureen Amirault purchased her first electric wheelchair in 2020, she had been living with muscular dystrophy for decades. Braces and a cane helped, but walking became too arduous, so she got a chair through a company called Numotion. The first few months were great. The headrest fell off, but Numotion fixed it in a matter of days.

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Bayer secures full ownership of Bayer Zydus Pharma, acquires remaining 25 per cent stakes

Express Pharma

Bayer Pharmaceuticals and Zydus Lifesciences announced the successful conclusion of their joint venture (JV) – Bayer Zydus Pharma. The 50:50 joint venture was established on January 28, 2011, for the sales and marketing of pharmaceutical products in India. Bayer is now securing full ownership of the entity, as per pre-agreed JV terms. A press statement from Bayer informed, “The JV successfully leveraged the strengths of both companies to better serve the fast-growing Indian market.

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The top pharmaceutical companies by R&D expenditure

Pharmaceutical Technology

From Merck & Co to Sanofi, Pharmaceutical Technology lists the leading pharmaceutical companies spending the most on R&D in 2023.

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Pfizer’s strong Vyndaqel sales draw attention to rare disease drug’s patent life

BioPharma Dive

Sales of the transthyretin amyloidosis treatment widely beat Wall Street forecasts in the first quarter. The company aims to extend its patent exclusivity.

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12 Questions with Dr Jay Shah

pharmaphorum

Get to know Dr Jay Shah, a prominent figure in the field of cardiovascular medicine, as he answers 12 intriguing questions about his role as Chief Medical Officer at Aktiia and his insights into the field.

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What we’re starting to learn about H5N1 in cows, and the risk to people

STAT

The H5N1 bird flu virus has been around for decades, and the damage it wreaks on chickens and other poultry is well documented. But the recent discovery that the virus has jumped into dairy cattle — whose udders seem to be where the virus either infects or migrates to — has dumbfounded scientists and agricultural authorities. Questions for which there are pretty clear answers when it comes to birds are suddenly unsettled science in cows.

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Latus Bio secures $54m for CNS gene therapy development

Pharmaceutical Business Review

The financing round is co-led by 8VC and DCVC Bio, with contributions from Samsung Life Science Fund, The Children’s Hospital of Philadelphia Foundation, Benjamin Franklin Technology Partners, Modi Ventures, and Gaingels. Latus Bio, emerging from the lab of co-founder professor Beverly Davidson at the Children’s Hospital of Philadelphia, is utilising proprietary technologies to develop CNS gene therapy candidates.

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Cambridge study finds AI more accurately assesses eye problems compared to doctors

Pharma Times

GPT-4 is trained on datasets to offer eye-related advice, diagnosis and management suggestions

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Tiffany Capps: A (CPESN) Beacon of Excellence

PioneerRx

“There's just so many things out there for pharmacies to maximize,” says Tiffany Capps, a pharmacy tech and CPESN’s Pharmacy Operations and Communications Lead.

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Prevention revolution: How digital tools can help us get ahead of health problems

pharmaphorum

Discover how digital tools can provide insights to help us. Digital technology could be a game-changer that offers the elusive promise of tackling the root cause, not just the conditions themselves, when it comes to human health.

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With younger women getting breast cancer, national panel lowers mammogram screening age to 40

STAT

A national advisory panel significantly lowered the age recommendations for screening mammography on Tuesday, saying that all women should start breast cancer screening at age 40, rather than 50, and continue every other year until age 74. The previous recommendations from the panel, the United States Preventive Services Task Force, suggested that women make an individual choice on getting mammography from ages 40 to 49.

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