European Pharmaceutical Review

MARCH 19, 2024

With a wider focus on sustainability in the industry, continuous bioprocessing aligns with these goals due to its ability to require less resources when compared to batch processing, the research stated. These advancements “aim to optimise productivity, increase yield, and enhance product quality while reducing overall production costs.”

Documentation 67

Documentation 67

European Pharmaceutical Review

NOVEMBER 16, 2023

Could centrifugal bioreactor accelerate cell-therapy manufacturing? This can be particularly beneficial for small and mid-sized manufacturers who may have limited resources, the author shared.

73

73

Syner-G

SEPTEMBER 15, 2023

Upstream processing advancements encompass fed-batch processes , improved cell culture media, advanced feeding strategies, and tailored bioreactor control. Regulators will oversee the process through clinical trials and commercialization and are valuable resources themselves.

Drug Development 59

Drug Development Documentation Process Improvement Compounding 59

European Pharmaceutical Review

AUGUST 29, 2022

Lastly, if capacity or resources are the limiting factors, full-service media development and testing can be conducted at FUJIFILM Irvine Scientific facilities. Finally, the media can be optimised for culture in bioreactors, with the goal of identifying several candidates for confirmation at the client’s site.

Process Improvement 85

Process Improvement 85

Pharmaceutical Technology

MARCH 22, 2023

Process intensification can loosely be described as making more product with the same or fewer resources. For example, running a bioreactor in perfusion mode instead of batch, or using continuous instead of batch chromatography. Existing technologies could also be run in a different way.

Documentation 52

Documentation Communication 52

European Pharmaceutical Review

DECEMBER 26, 2023

Achieving cost optimisation requires identifying opportunities for process simplification, improving productivity and optimising resources Gene therapy products are very complex and manufactured with a cellular host substrate, which makes analytical characterisation far more challenging.

Drug Pricing 82

Drug Pricing Packaging Vaccines Drug Development 82