European Pharmaceutical Review

JUNE 28, 2022

These molecules are proven to be effective at much smaller dosage levels than traditional APIs. During the last decade demand for analytical chemistry on HPAPIs has grown rapidly, mainly due to advances in clinical pharmacology and oncology research. Some examples of HPAPIs are cytotoxic compounds and hormones such as oestrogen.

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Dosage Clinical Pharmacology Compounding 72

ALiEM - Pharm Pearls

NOVEMBER 1, 2023

[1,2] Severe symptoms such as hypovolemia, shock, metabolic acidosis Persistent and severe GI symptoms Lethargy or toxic appearance Serum iron level greater than 500 mcg/dL What is the dosage of deferoxamine for iron toxicity? [1] Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson’s disease.

Clinical Pharmacology 161

Clinical Pharmacology Dosage Compounding 161

Big Molecule Watch

SEPTEMBER 25, 2023

indication(s), dosing regimen(s)), strength(s), dosage form(s), and route(s) of administration) described in its Full Prescribing Information.” Biosimilarity of [BIOSIMILAR OR INTERCHANGEABLE BIOSIMILAR PRODUCT’S PROPRIETARY NAME] has been demonstrated for the condition(s) of use (e.g.,

Labelling 62

Labelling Biosimilars Adverse Reactions Dosage 62

Pharmacy Joe

JANUARY 10, 2021

In 1989, a study in the Journal of Clinical Pharmacology compared 10, 30, and 90 mg of IM ketorolac with placebo in 126 patients with cancer pain. Either FDA approval of a lower dosage size or an automatic substitution policy would likely be required to get IV ketorolac doses down to 10 mg routinely.

Clinical Pharmacology 40

Clinical Pharmacology Inpatient Dosage Documentation 40

RX Note

JANUARY 21, 2023

Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)

Compounding 40

Compounding Community Pharmacies Clinical Pharmacology Dosage 40

Pharmaceutical Technology

FEBRUARY 17, 2023

In January, amidst calls to improve patient safety by optimizing licensed drug formulations, the FDA released a draft guidance that signalled a departure from the most commonly used method of identifying a new therapy’s ideal dosage. The focus on identifying the ideal drug dosage is not new. What is drug dose optimisation?

Dosage 115

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