Tue.Mar 05, 2024

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How the U.S. is sabotaging its best tools to prevent deaths in the opioid epidemic

STAT

The opioid overdose epidemic has burned through the U.S. for nearly 30 years. Yet for all that time, the country has had tools that are highly effective at preventing overdose deaths: methadone and buprenorphine. These medicines are cheap and easy to distribute. People who take them use illicit drugs at far lower rates, and are at far lower risk of overdose or death.

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ACMT Toxicology Visual Pearl: The Bark with Some Bite

ALiEM - Pharm Pearls

Which medication can be derived from the bark of the pictured tree? Aspirin Atropine Colchicine Quinine Reveal the Answer 1. Aspirin Background The photo shows a weeping willow, a member of the Salix genus of trees. Willow tree bark contains salicin from which aspirin (acetylsalicylic acid) can be derived. For over 3500 years, willow bark has been used as a traditional medicine to treat fevers and pain [1].

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Watch: Why fentanyl withdrawal is agony and how medication can prevent it

STAT

Over 2 million Americans have opioid use disorder, according to some estimates. Illicit opioids such as heroin and fentanyl were responsible for over 80,000 U.S. overdose deaths in 2023. Despite the known risks, these drugs are notoriously hard to stop using — due in large part to how debilitating withdrawal can be.

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HIV isn’t ‘solved,’ but a doctor who treated some of the first patients hopes to finally deliver a cure

PharmaVoice

From San Francisco in the 80s to a gene therapy prospect, Dr. Marcus Conant looks back on his long fight against the virus — and if the industry is close to ending the epidemic.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Harvard longevity scientist sparks furor with claim about reversing aging in dogs

STAT

Renowned Harvard University geneticist and longevity researcher David Sinclair recently made an astonishing assertion: Scientists had developed the first pill — well, a soft, beef-flavored chew — “proven to reverse aging” in dogs. Which miracle molecules delivered this supposed scientific breakthrough, he didn’t say.

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Biotech IPOs heated up to start 2024. Will the surge last?

PharmaVoice

Following the sector’s best IPO start in three years, industry insiders shared what they expect to see in the months ahead.

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More Trending

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Manifesto for community pharmacy launched ahead of general election

The Pharmacist

Several pharmacy bodies have joined forces to launch a joint manifesto for community pharmacy ahead of the general election expected this year. The document calls on election candidates to back a six-point plan to ‘unleash the potential of community pharmacy’ and highlights the need for more funding, workforce support, a review of the medicines supply […] The post Manifesto for community pharmacy launched ahead of general election appeared first on The Pharmacist.

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STAT+: FDA clears first over-the-counter continuous glucose monitor

STAT

For the first time, anyone in the United States will soon be able to buy a continuous glucose monitor without a prescription. The Food and Drug Administration authorized Dexcom on Tuesday to start selling a new product, called the Stelo, to adults who do not use insulin. The product is scheduled to hit the market this summer.    The Stelo product is explicitly designed for people with type 2 diabetes who are not reliant on insulin, or people without diabetes who are curious about

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Surprise Enhertu rejection follows NICE process change

pharmaphorum

NICE has rejected the use of AstraZeneca and Daiichi Sankyo’s Enhertu as an NHS treatment for advanced HER2-low breast cancer, a decision that the companies have described as “devastating”.

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It’s time to stop treating menopause like a disease, researchers argue in series of Lancet articles

STAT

One in eight people is postmenopausal, and about 50 million women enter menopause every year. A new essay published on Tuesday in The Lancet argues that it’s time to stop treating them like patients suffering from a disorder. The article calls for a reframing of menopause and a management approach that is not simply focused on medical interventions that relieve symptoms.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Alnylam, Roche blood pressure drug scores in second mid-stage trial

BioPharma Dive

The study results further validate Roche’s recent decision to acquire rights to the drug, which is being developed for people with a stubborn form of hypertension.

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FDA advisory panel recommends a streamlined flu vaccine for next fall

STAT

When Americans line up for flu vaccines next fall, they will almost certainly be getting vaccines that no longer contain protection against a family of flu viruses that appears to be extinct. Experts who advise the Food and Drug Administration on vaccine-related issues voted unanimously on Tuesday to recommend that the FDA approve trivalent flu vaccines for the 2024-2025 season, instead of the quadrivalent, or four-in-one, shots that have been the industry standard for the past decade or so.

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NICE backs frontline use of Jemperli in endometrial cancer

pharmaphorum

GSK’s PD-1 inhibitor Jemperli has been cleared for use by the NHS as a first-line treatment for a specific type of endometrial cancer, making it an option for around 580 women across England, Wales and Northern Ireland.

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Q&A: Microsoft research head explains how generative AI could help doctors be more human

STAT

Generative AI is having a moment. Peter Lee, who oversees Microsoft’s approach to health care and co-authored the 2023 book “ The AI Revolution in Medicine: GPT-4 and Beyond, ” calls it “the most transformative tool ever developed in all aspects of health care and medicine.” Microsoft has been collaborating with the organization OpenAI for several years, so when OpenAI released ChatGPT in November 2022, Lee quickly realized there was a need to educate the medic

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Opportunities for cell and gene therapy landscape remain high but so does challenges: GlobalData

Express Pharma

Cell and gene therapies (CGTs) have been gaining traction within the medical community as treatment options that are expected to replace lifelong management of chronic diseases with fewer number of doses, which could offer significant benefits for both patients and strained healthcare systems. However, alongside these opportunities, regulatory barriers and cost concerns pose challenges to their widespread adoption, according to GlobalData.

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STAT+: WTO proposal for Covid diagnostics and therapeutics waiver is abandoned

STAT

After 18 months of debate, the World Trade Organization failed to adopt a controversial proposal to waive intellectual property protection for Covid-19 diagnostics and treatments, ending a furious attempt by civil society groups to bolster global access to needed medical products. The failure was not a surprise. Since the proposal was introduced, the pharmaceutical industry — and several key countries where large drugmakers are headquartered, including the U.K. and Switzerland — su

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Pharmacist Movie Roles You Might Not Know About

PioneerRx

“My life is a movie.” That saying is usually reserved for winning the Super Bowl or finally going to a concert of your favorite artist. Maybe you felt that way.

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Air quality improvements belie rising racial and ethnic disparities in pollutant-related deaths, study finds

STAT

The U.S. is making progress in reducing the public health consequences of air pollutants and fine particulate matter. But these improvements have not benefited everyone equally, according to a new study published on Wednesday in the journal Environmental Health Perspective. Researchers found an overall drop from 2010 and 2019 in death and disease linked to nitrogen dioxide (NO2), an air pollutant produced from fossil fuel burning, and fine particulate matter (PM2.5) pollution.

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Clerkenwell Health calling for volunteers with PTSD to trial new psychoactive drug

Outsourcing Pharma

Clerkenwell Health, a company that delivers clinical trials for the treatment of complex mental health volunteers for trials into the use of psychoactive medications for treating PTSD, is in search of 40 ex-military volunteers.

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Opinion: How ideas from ancient Greece like ‘a bun in the oven’ continue to affect reproductive health policy

STAT

On Jan. 22, 1973, the U.S. Supreme Court handed down its decision in Roe v. Wade, declaring a Texas law prohibiting abortion, and similar laws in other states, to be unconstitutional. Not quite 50 years later, on June 24, 2022, the Supreme Court overturned the Roe decision. In Dobbs v. Jackson Women’s Health Organization, the court declared: “The Constitution does not confer a right to abortion.

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Can creative analytics solve your D2C paid search headache?

pharmaphorum

Learn how creative analytics can help solve your Direct-to-Consumer paid search challenges. Discover how data-driven insights can optimise your performance with HCPs.

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STAT+: Large insurers say up to one-quarter of claims run through Change Healthcare

STAT

Some of the country’s biggest health insurers said Tuesday that up to one-quarter of their claims are run through Change Healthcare, UnitedHealth Group’s technology company that sustained a massive cyberattack two weeks ago. Speaking at investor conferences, executives from Humana, Elevance Health, and CVS Health, which owns Aetna, said the biggest impact they’re seeing is fewer bills coming in from providers.

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Novo Nordisk looks set to add another string to Ozempic bow

pharmaphorum

Novo Nordisk’s GLP-1 agonist Ozempic has shown efficacy in yet another indication, achieving a 24% reduction in kidney disease-related events in people with type 2 diabetes and chronic kidney disease (CKD) in the FLOW trial.

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Where’s Lilly’s Alzheimer’s approval?

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here. I’d like to heartily recommend you  check out Part 1 of The War on Recovery , a yearlong STAT investigation into how the U.S. denies lifesaving medications to people with opioid addiction.

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Transitioning from traditional surgical methods to the innovative use of stem cells

pharmaphorum

In today’s podcast, host Nicole Raleigh welcomes Dr Jeffrey Gross, founder of ReCELLebrate, neurological surgeon, and expert in the field of regenerative medicine, to discuss the recent appetite for the use of stem cells for longevity and explores the ‘health span’ notion that is being ever more frequently spoken of.

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STAT+: Q&A: Nora Volkow on how to get ‘at least 50% less people dying’ from opioid overdose

STAT

In 2003, the year Nora Volkow was appointed director of the National Institute on Drug Abuse, roughly 4,000 Americans died of opioid overdose. In the two decades since, the overdose crisis has morphed into a full-fledged public health emergency, with 80,000 Americans dying from opioid overdoses each year. But in that stretch, relatively little has changed about the way the U.S. treats opioid addiction.

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New BeiGene Head of Europe, Global Clinical Operations appointed

European Pharmaceutical Review

BeiGene has appointed Pilar de la Rocha as its new Head of Europe, Global Clinical Operations. The biotech’s new appointment underlines its commitment to advancing clinical development initiatives in the European region. The company highlighted that 35 percent of patients enrolled in its clinical trials are based in Europe. Pilar de la Rocha brings more than two decades of experience in oncology clinical development to the role, according to Beigene.

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Ransom speculation as US reels from health cyberattack

pharmaphorum

As healthcare facilities and pharmacies try to recover from one of the most disruptive cyberattacks in US history, reports have emerged that the perpetrators may have received a hefty ransom payment.

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Dragons' Den investment spurs innovation in dementia-friendly finance

Outsourcing Pharma

Jayne Sibley, the mastermind behind Sibstar, a debit card and mobile app aimed at those with dementia has secured a substantial Â125K investment from BBC Dragonsâ Den investors Sara Davies and Deborah Meaden.

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Venus Remedies gets first incentive of Rs.7.50 crore under PLl scheme

Express Pharma

Venus Remedies has received its first disbursement of Rs 7.5 crore under the Central government’s Production Linked Incentive (PLl) scheme for the financial year 2022-23, which covers 75 per cent of the total incentive due to the company for the year. Selected under the PLl scheme in December 2021, Venus Remedies is amplifying its manufacturing infrastructure and expanding its product portfolio.

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Analytica 2024 in overview

European Pharmaceutical Review

International participation and trending topics With over 900 exhibitors, analytica 2024 promises an impressive lineup. Both national and international market leaders are represented, with a noticeable increase, particularly from China. Innovative startups and smaller companies show great interest in the fair, which has established itself as a springboard for new developments and products.

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Expert Speak | Dr Raktim Chattopadhyay, Founder & CEO, Esperer Nutrition; Member of Task Force, Nutraceutical Council to PSA office, Government of India

Express Pharma

In this episode of the Express Pharma – Nutrify Today Boardroom series, Dr Raktim Chattopadhyay, Founder & CEO, Esperer Nutrition speaks on the need for in-depth clinical research and validation backing all products from Esperer Nutrition, which sets them apart as disease-specific nutritional interventions to help patients and doctors manage and recover from cancer, and non-communicable diseases (NCDs).

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Pharma’s Medicare counteroffers are all in, says HHS

pharmaphorum

HHS says all pharma companies affected by Medicare price negotiations have filed counteroffers, trumpeting the milestone as a sign the process is working

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Drug Channel Implications of the Inflation Reduction Act (NEW Live Video Webinar)

Drug Channels

Dr. Adam J. Fein, president of Drug Channels Institute (DCI) and the author of Drug Channels , invites you to join him for DCI’s latest live video webinar: Drug Channel Implications of the Inflation Reduction Act This event will be broadcast live on Friday, April 5, 2024, from 12:00 p.m. to 1:30 p.m. ET This post describes the event and explains how to purchase a registration.

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Words matter: The power of language in cancer discussions

pharmaphorum

Explore the impact of language in cancer discussions and how it can influence patients' perceptions of therapy and oncology treatments. Understand the power of words in the context of cancer care.

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