Sun.Jun 04, 2023

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STAT+: Immunogen drug prolongs survival of women with advanced ovarian cancer

STAT

CHICAGO — An antibody that delivers chemotherapy directly to tumor cells extended the lives of women with a form of advanced ovarian cancer in a large study, researchers reported Sunday. The drug, called Elahere, is made by the biotech company Immunogen. It was granted conditional approval in the U.S. last November based on preliminary evidence showing it shrank tumors.

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Brexpiprazole For Alzheimer’s Agitation – Is The Juice Worth The Squeeze?

Med Ed 101

Earlier this month the FDA approved Rexulti (Brexpiprazole) for the treatment of agitation in patients with dementia due to Alzheimer’s. Originally approved as an atypical antipsychotic used for schizophrenia, or an adjunct therapy for major depressive disorder, Rexulti finds itself alone as the only medication for this indication. In the clinical trials, the Cohen-Mansfield Agitation […] The post Brexpiprazole For Alzheimer’s Agitation – Is The Juice Worth The Squeeze?

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STAT+: Targeted drug greatly slows progression of a brain cancer

STAT

CHICAGO – An experimental drug dramatically slowed the growth of glioma, a type of brain cancer, if the tumor carried a specific type of genetic alteration, researchers said Sunday, potentially sparing patients exposure to radiation and chemotherapy. The drug, vorasidenib, is made by Servier Pharmaceuticals, a privately held drugmaker based in France.

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Leading innovators with viral vectors for the pharmaceutical industry

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Viral vectors.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Biotechs face challenges as the industry’s annual bash returns to Boston

STAT

The world has changed since 2018 when the Biotechnology Innovation Organization last brought its annual road show to Boston, complete with entrepreneurial boot camps, beer-flowing receptions, and four days of nonstop networking. Since then, a global pandemic showcased the industry’s prowess in rushing out lifesaving vaccines — elevating scientists to the status of saviors, at least for a fleeting moment.

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ASCO 2023: Keytruda becomes a new option in perioperative NSCLC  

Pharmaceutical Technology

Early-stage non-small cell lung cancer (NSCLC) is typically treated with surgery followed by adjuvant therapy (chemo ± radiation) in patients deemed to be at higher risk. The use of a pre-surgical course of drug treatment (neoadjuvant), is not well established thus far and can differ substantially between countries and even hospitals within the same country.

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Episode 823: Quantitative Neuromuscular Monitoring To Guide Sugammadex Use

Pharmacy Joe

In this episode, I’ll discuss the Management of muscle relaxation with rocuronium and reversal with neostigmine or sugammadex guided by quantitative neuromuscular monitoring. Episode 823: Quantitative Neuromuscular Monitoring To Guide Sugammadex Use Subscribe on iTunes , Android , or Stitcher Sugammadex is an effective but expensive neuromuscular blocking reversal agent compared with the previous standard of care, neostigmine.

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Innovation in immuno-oncology: Leading companies in T-cell culturing

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Immuno-oncology in Pharmaceuticals: T-cell culturing.

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ASCO: AZ gets a practice-changing win in lung cancer

pharmaphorum

ASCO: AZ gets a practice-changing win in lung cancer Phil.

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Leading innovators in transcription factors for genetically modified cells for the pharmaceutical industry

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Innovation in Pharmaceuticals: Transcription factors

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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ASCO: Can Imfinzi bring immunotherapy to ovarian cancer?

pharmaphorum

ASCO: Can Imfinzi bring immunotherapy to ovarian cancer? Phil.

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Developing and Executing a Campaign to Boost Web Traffic by 85%

PharmaTech

Read about how we helped The Clinician increase users to their website by 85%, new users by 92%, and sessions by 94%

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What Is Quercetin? Overview, Benefits, Sides Effects, Uses And Properties

Welltopia Pharmacy

Quercetin is commonly utilized to treat heart and blood vessel conditions and as a preventive measure against cancer.

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The Life Science Marketer's Checklist

PharmaTech

A robust marketing strategy is key to building brand equity and an effective, efficient sales pipeline—the overall goal. And the best way to develop that all-important strategy is to take stock of where you’re at and assess your resources. To aid in this self-assessment, we’ve developed The Life Science Marketer’s Checklist of must-haves for marketing professionals in the industry.

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Gilead and Arcus Present P-II Study (ARC-7) Results of Domvanalimab as 1L Treatment of Non-Small Cell Lung Cancer at ASCO 2023

PharmaShots

Shots: The interim analysis from the P-II study evaluating domvanalimab + zimberelimab (doublet) & domvanalimab + zimberelimab and etrumadenant (triplet) vs zimberelimab monotx. in a ratio (1:1:1) in 150 patients with PD-L1 TPS ≥50% and no EGFR or ALK mutations As the time of data cutoff of Feb 2023, improvement in PFS vs zimberelimab monotx. with a median follow-up time of ~18mos., 33% reduction in risk of disease progression or death for doublet & 28% for triplet Zimberelimab monotx

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Supporting Biotech and Pharma Companies Using Imaging Endpoints in Clinical Trials

PharmaTech

Medical imaging is a key factor in successful clinical trials. At Bracken, our experts bring storied experience from the intersection of medical imaging and clinical research. Our imaging consultants can serve as an intermediary between you and and an imaging CRO to launch a complete and accomplished clinical trial.

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Stock Handling

RX Note

Introduction The Good Distribution Practice guidelines are designed to ensure the quality, safety and integrity of products throughout the supply chain. These guidelines help prevent the introduction of substandard or falsified products into the market. Receiving Upon receipt, each incoming delivery should be checked against the relevant documentation and physically verified by Label description Type and quantity (subdivided according to the supplier's lot number if necessary) Relevant purchase

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New FGFR Inhibition Therapies Show Promise in Intrahepatic Cholangiocarcinoma

Pharmacy Times

Biliary tract cancers have become the model for precision oncology because of its complex molecular landscape.

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Pharmaceutical Thermal Packaging 4.0: Sonoco ThermoSafe

Pharmaceutical Commerce

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Addition of Pembrolizumab to Chemotherapy Can Significantly Improve Survival Outcomes in Patients with Cervical Cancer

Pharmacy Times

Expert discusses the long wait for an effective therapeutic option for persistent, recurrent, or metastatic cervical cancer and the potential widespread benefits of antibody drug conjugates like pembrolizumab.

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Which pharmaceutical companies have the most SPCs in Italy?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Italy. SPCs are used in European Union and select others to encourage pharmaceutical innovation by compensating… The post Which pharmaceutical companies have the most SPCs in Italy? appeared first on DrugPatentWatch - Make Better Decisions.

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With Perioperative Pembrolizumab, Event-Free Survival for Early-Stage Lung Cancer Was 62% at the Interim Analysis of Phase 3 KEYNOTE-671

Pharmacy Times

Expert said these striking results, coupled with benefits across all subgroups and potential overall survival, suggests efficacy for adults with early-stage non-small cell lung cancer.

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Leading innovators in transcription factors for AAV for the pharmaceutical industry

Pharmaceutical Technology

The pharmaceutical industry continues to be a hotbed of innovation, with activity driven by the evolution of new treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 633,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on on Innovation in Pharmaceuticals: Transcription facto

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Targeting Folate Receptor Alpha is Ideal for Ovarian Cancer Treatment

Pharmacy Times

FR alpha expression is limited on normal cells, but upregulated on cancers such as ovarian, endometrial, and triple-negative breast cancers.

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Drug Storage

RX Note

Introduction Once, I received a query from a ward nurse: If a product label mentioned that "Do not store over 25°C", is it fine for us to keep the medication in fridge? What does a cool place on the product label mean? Tips for Patients Storing medication properly is important to ensure it works as intended to prevent poisoning accidents. Read the label to know the recommended storage temperature range.

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Connecticut Favorites – Beauty

The Luxe Pharmacist

Hi friends, I get so many questions about where I get my hair, lashes, nails, etc done in Connecticut so I figured I’d do a round up blog post of all my favorites places! This version is all things beauty in CT, but I hope to expand to restaurants, coffee shops and more in the future so let me know in the comments if there’s anything specific you want to see in a future CT round up!

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Dr Reddy’s completes Phase I study of DRL_TC, a tocilizumab biosimilar candidate

Express Pharma

Dr Reddy’s Laboratories announced that its tocilizumab biosimilar candidate, DRL_TC, successfully met its primary and secondary endpoints in a Phase I study. This Phase I study used an intravenous (IV) formulation to evaluate the pharmacokinetic equivalence, safety and immunogenicity of Dr Reddy’s tocilizumab biosimilar candidate in comparison to reference products.

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Drug Complaint

RX Note

Introduction Once, a senior pharmacist asked me a very thoughtful question: other than complaining on the current situation, what actions have you taken to improve it? Healthcare Professionals At workplace, have you ever received complaints from patients that: The new MDI canister is empty? The new generic brand of a drug is not as effective as the old generic brand?

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Organic Foods

RX Note

Introduction Organically grown foods are foods that are grown or processed without the use of synthetic fertilizers or pesticides. Organic farmers attempt to protect the environment by using natural matter (e.g., aged manure, humus, and compost) for fertilizer and biologic methods of pest control (e.g., crop rotation and natural insect predators like lady bugs).