Thu.Sep 28, 2023

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Exodus of life scientists from academia reaches historic levels, new data show

STAT

New data released Thursday by the National Science Foundation show the exodus of young life scientists from the Ivory Tower to industry has reached the highest level in nearly three decades, deepening concerns about the future of academic science in the U.S. Among newly minted life science Ph.D.s in 2022 who had firm next steps, roughly 53% planned to pursue postdoctoral research, a temporary period of additional training that is virtually a requirement for those hoping to land a faculty job.

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Pfizer CEO Albert Bourla led Big Pharma bonus payouts over 5 years — but he’s no Elon Musk

PharmaVoice

A recent report showed how pharma’s bonuses pale in comparison to other industries, but several execs still rake in hefty packages.

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Did the government get a bad deal on the Covid-19 boosters?

STAT

WASHINGTON — After Pfizer and Moderna hiked the prices of their Covid-19 vaccines this year, the federal government will now pay nearly three times more than it did previously for each dose. And it’s paying more than countries that did far less to support vaccine development. Health and Human Services Secretary Xavier Becerra glossed over the dramatic increase in the amount the government is paying for vaccines in a public appearance last week, when he got vaccinated at a CVS pharm

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How pharma marketers can reclaim the drug pricing narrative

PharmaVoice

As Medicare negotiations heat up, it’s more important than ever for pharma companies to communicate their value. Here’s how.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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She got off dialysis. Her doctor thinks others with acute kidney injury can too

STAT

SAN FRANCISCO — It was during some of the darkest days of the pandemic — November 2020 — when Melissa Lawson, 36, was helicoptered from an emergency room in Santa Rosa, Calif., to a hospital here, her blood so thick with white blood cells doctors thought she might not survive the night. She did, after undergoing a procedure to clear her blood.

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AstraZeneca and SAS link up on AI and analytics

Pharma Times

Collaboration will enable teams across the organisation to increase clinical research innovation - News - PharmaTimes

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Women in Life Science Denmark launches leadership drive

Pharma Times

Initiative has been designed to support career advancement for women across the life sciences - News - PharmaTimes

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A STAT analysis shows how top drug companies are starting to take action on climate

STAT

This article is adapted from STAT’s exclusive analysis in the STAT Report: “Climate rankings: How top drug companies measure up in combating climate change.” D rug companies are major contributors to climate change, both through direct greenhouse gas emissions and especially through their supply chains. But the pharmaceutical industry has lagged behind others when it comes to understanding and cutting down on its climate impact.

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PulmCrit Hot Take: Aggressive glycemic control is dead (TGC-Fast Trial)

EMCrit Project

background Today the Van de Bergh group in Belgium released a RCT investigating tight versus liberal glycemic control in the ICU. Before diving into this study, let's take a walk down memory lane. Major interest in tight glycemic control in the ICU began in 2001 with an RCT by the same group of investigators, also […] EMCrit Project by Josh Farkas.

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Opinion: Congress could stop free public access to government-funded research

STAT

Have you ever needed to read a research paper, only to find it was locked behind a paywall? Your next step was likely to search on Sci-Hub , an illegal repository created by Kazakh graduate student Alexandra Elbakyan, that provides free access to millions of research papers. While Sci-Hub is controversial, its widespread use points to a crucial question: Shouldn’t taxpayer-funded research be freely and immediately accessible to the public?

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Pharmacy professionals have 'ethical responsibility' to mitigate climate risks to health

The Pharmacist

The International Pharmaceutical Federation (FIP) has called for action on climate change, with a particular emphasis on environmental sustainability within pharmacy. In a policy statement published this week, FIP emphasised that pharmacy practice and medicines cause greenhouse gas emissions and pollution and therefore contribute to climate change and ecological damage and thus threaten human health. […] The post Pharmacy professionals have 'ethical responsibility' to mitigate cl

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STAT+: Brigham and Women’s exec opens up about the Dana-Farber Cancer Institute split, and what it means for the future of cancer care

STAT

The severing of ties between two of Boston’s biggest health care giants has placed one of the nation’s largest health care systems in the position of figuring out how, exactly, to fill a new hole in its oncology services, at a time when cancer care is changing rapidly. Earlier this month, Dana-Farber Cancer Institute surprised the medical community and even its partner, Brigham and Women’s Hospital, when it announced that it would end their nearly 30-year collaboration.

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Generative AI-focused biotech startup Evozyne raises $81m

Pharmaceutical Technology

The company’s algorithms put proteins through millions of years of simulated evolution to identify potential functional candidates.

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Machine learning could help predict risk of preterm birth using wearables data

STAT

For all their potential to drive changes in health, wearables have struggled to gain a foothold in medicine. The dramatic changes during pregnancy are a fertile ground to test their potential, though — and new research shows how applying machine learning methods to streams of data from wearable devices could be used to understand the mystery of premature birth.

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ADHD medicine shortage will prompt supply queries

The Pharmacist

Community pharmacies may be contacted by GPs regarding the availability of medicines used to treat ADHD in the coming weeks, amid a national shortage. A national patient safety alert issued this week said there were ‘supply disruptions’ of various strengths of methylphenidate, lisdexamfetamine and guanfacine. With the issues expected to continue until December for some […] The post ADHD medicine shortage will prompt supply queries appeared first on The Pharmacist.

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STAT+: Drug industry payments to eye docs boosted Medicare spending on pricier treatments

STAT

Ophthalmologists who accepted payments from drug companies were less likely to prescribe a cheaper medicine to treat an eye disease that causes blindness in older people, rather than a pair of more expensive alternatives, according to a new study. This led Medicare to spend an additional $643 million during a recent six-year period. Specifically, physicians who received money prescribed Avastin, an older cancer medicine, 28% of the time for combating age-related macular degeneration.

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Gritstone wins ‘Project NextGen’ funding to run head-to-head COVID vaccine study

BioPharma Dive

In a note to clients, Evercore ISI analyst Jonathan Miller described the Project NextGen contract for Gritstone as “certainly a nice signal of continued government support for COVID research.

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STAT+: What will Novo’s VC do with its influx of cash? Don’t expect obesity investments

STAT

The Danish pharmaceutical company Novo Nordisk has shepherded all kinds of medical innovation in the 110 years since it was founded. But the booming success of its diabetes and obesity drug is unlike anything executives have seen before. The company’s mid-year operating profit jumped from 37.5 billion danish kroner in 2022 to 48.9 billion danish kroner this year — “probably the strongest growth in the history of the company,” Chief Financial Officer Karsten Munk Knuds

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CymaBay launches study into drug for liver scarring in patients with compensated cirrhosis

Outsourcing Pharma

A study to evaluate the effect of seladelparm, a small molecule treatment by CymaBay Therapeutics, Inc. on patients with cirrhosis was announced this month (September 21).

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STAT+: Pharmalittle: FDA advisers vote overwhelmingly against ALS treatment; weight-loss drugs scrutinized over reports of suicidal thoughts

STAT

Top of the morning to you, and a fine one it is. Despite overcast skies, we are enjoying the hustle-bustle of passing cars, barking dogs, and other signs of life as we rev up for another day. The coffee kettle is firing up — maple bourbon is our choice cup of stimulation — and the backing soundtrack is in order. So time to get cracking.

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Driving Dosage Form Developments

PharmaTech

Dosage forms are being shaped by numerous factors, with patient-centricity continuing to be an important driver of decisions in development.

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Listen: Who discovered GLP-1? Plus: BrainStorm at the FDA and biotech’s slump

STAT

When is negative data positive enough? Who gets credit for scientific breakthroughs? And wasn’t biotech supposed to bounce back? We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. Our colleague Elaine Chen joins us to explain the story of Svetlana Mojsov, a chemist who played a vital role in the discovery of GLP-1 who has spent decades fighting for proper recognition.

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European PFAS restriction could jeopardise pharmaceutical manufacturing

European Pharmaceutical Review

According to the European Federation of Pharmaceutical Industries and Associations (EFPIA), more than 600 essential medicines are at risk if a proposed restriction on the use of fluorinated substances, per- and polyfluoroalkyl substances (PFAS) across pharmaceutical manufacturing in the EEA, is implemented. A total ban [of PFAS] would see medicines’ manufacturing in the EU grind to a halt in under three years” EFPIA stated that the EU chemical legislation under The Regulation on the regist

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SPDS announces DRPI 2023 World-Grant finale

Express Pharma

It is a global online dissolution research presentation international competition for Masters/Ph.D students The Society for Pharmaceutical Dissolution Sciences (SPDS) in association with the American Association of Pharmaceutical Scientists (AAPS) has announced the DRPI 2023 World Finals, a global online research presentation competition for pharma students working in the dissolution science and allied areas.

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Counterfeit Meds: Fighting the Forgers

Pharmaceutical Commerce

Questions and considerations for pharmaceutical companies in designing and executing strategies to curb the incidence of fake drugs.

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Guaranteeing resilience in vaccine manufacturing

European Pharmaceutical Review

There has been a steady stream of developments in the vaccine manufacturing space throughout 2023. A notable milestone was Moderna’s announcement in April that it had, following finalisation of a ten-year strategic partnership with the UK Government, commenced construction of its mRNA vaccine manufacturing technology centre. Known as MITC, or the Moderna Innovation and Technology Centre, the facility is located in Harwell, Oxfordshire and is expected to become operational in 2025.

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Reshaped Priorities Pave Cold Chain Path

Pharmaceutical Commerce

How recent advancements in practice and technology have ushered in a new era of pharmaceutical logistics.

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Call for mandatory training on learning disabilities and autism for pharmacists

The Pharmacist

Training on learning disabilities and autism should be compulsory for all pharmacists in England, the Royal Pharmaceutical Society (RPS) has said. The Health and Care Act 2022 introduced a requirement for all health and social care staff registered with the Care Quality Commission (CQC) to receive learning disability and autism training appropriate to their role […] The post Call for mandatory training on learning disabilities and autism for pharmacists appeared first on The Pharmacist.

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Understanding and addressing care disparities in rare cancers

pharmaphorum

Understanding and addressing care disparities in rare cancers Mike.

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Finding New Value in Drugs: Q&A With Darius Lakdawalla, Chief Scientific Officer at EntityRisk

PharmExec

Lakdawalla speaks about how drugs aren’t being properly valued.

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Pfizer's first acute migraine treatment recommended by NICE

Outsourcing Pharma

The first treatment for acute migraine made by Pfizer Ltd has been recommended by the National Institute for Health and Care Excellence (NICE).

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J&J cancer drug combo beats Tagrisso in closely watched trial

BioPharma Dive

Interim results from a study called “Mariposa” found that a regimen of two J&J medicines improved progression-free survival versus AstraZeneca’s widely used therapy.

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CureVac claims advantage in BioNTech patent dispute

pharmaphorum

CureVac claims advantage in BioNTech patent dispute Phil.

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People with HIV offered hope of self-injected drug at home

The Guardian - Pharmaceutical Industry

GSK-controlled company works on developing patient-administered treatment by end of the decade One of the world’s largest commercial developers of HIV drugs is working on a treatment that can be injected by patients at home every two to three months by the end of the decade, saving them frequent visits to the clinic. ViiV Healthcare, a GlaxoSmithKline-controlled joint venture, makes 17 prescription HIV medicines, including the long-acting treatment cabotegravir, which was first approved in the U

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New patent for Maia Pharms drug BORTEZOMIB

Drug Patent Watch

Annual Drug Patent Expirations for BORTEZOMIB Bortezomib is a drug marketed by Accord Hlthcare, Apotex, Baxter Hlthcare Corp, Dr Reddys, Eugia Pharma, Fresenius Kabi Usa, Hospira, Jiangsu Hansoh Pharm, Meitheal,… The post New patent for Maia Pharms drug BORTEZOMIB appeared first on DrugPatentWatch - Make Better Decisions.

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