Wed.Jul 19, 2023

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Stanford president to resign after investigation finds he failed to ‘decisively and forthrightly’ correct research

STAT

In an abrupt turn, Stanford president and renowned neuroscientist Marc Tessier-Lavigne announced Wednesday that he will step down as the university’s leader. His resignation came after he learned the results of an extensive investigation into his past research, which confirmed data-manipulation in scientific papers that he co-authored and found that he took insufficient steps to correct them.

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As biologics boom, here’s how manufacturers are keeping up

PharmaVoice

Stevanato’s focus on biologic-related vials and delivery devices has put it in a unique position amid a quickly growing market.

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Cancer drug shortages deliver ‘gut punch’ to patients unsure if their survival odds will be undercut

STAT

Mairéad McInerney will never know if changes in her treatment plan have undercut her odds of surviving stage 3 triple-negative breast cancer. Critical shortages in cancer drugs have forced her to change course not once, but twice. The first time, her physicians flipped the order of her drug regimen because Taxol (paclitaxel), one of two drugs she was supposed to take, was not available, said McInerney, who was diagnosed in December 2022.

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AI’s great expectations

PharmaVoice

With AI expectations riding high, here’s a look at some areas where the technology could be most useful in drug development.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Genetic cheat code might explain why some people catch Covid but never get sick

STAT

In the earliest days of the Covid-19 pandemic, when the new coronavirus still appeared to be confined to China, public health authorities were divided over whether to declare the outbreak a global emergency. That changed once it became clear that the virus was silently spreading farther and faster than anyone realized — fueled by transmission among contagious people who didn’t feel sick.

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Engaging Communities through High-Impact Healthcare Sponsorships in the Pharmaceutical Industry 

Pharma Marketing Network

Sponsorships can be a powerful tool for pharmaceutical companies to engage with communities and make a positive impact on health and wellness. When done right, sponsorships can help pharmaceutical companies connect with their target audience, build relationships with key stakeholders, and promote their brand in a meaningful way. Here are some examples of how pharmaceutical companies can use sponsorships to engage communities: Sponsoring community health events: Pharmaceutical companies can s

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Content Marketing as a Sales Driver: Unlocking Your Business Potential in the Pharmaceutical Industry

Pharma Marketing Network

Content Marketing as a Sales Driver: Unlocking Your Business Potential in the Pharmaceutical Industry Content marketing is a long-term strategy that can help businesses of all sizes generate leads, increase brand awareness, and drive sales. By creating and distributing valuable content, businesses can attract and engage their target audience, position themselves as experts in their field, and build trust with potential customers.

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The kidney, in all its complexity, is captured in an atlas that could aid disease research

STAT

The kidneys are some of the most architecturally complex organs in the human body — intricate in a way that becomes frustrating when, for millions of people each year, they lose function.  It’s only in recent decades that scientists have been able to leverage new techniques, like the ever-growing list of “-omics,” to peer deep inside human cells.

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Creating Synergy: Aligning Brand Values with High-Impact Healthcare Sponsorships in the Pharmaceutical Industry 

Pharma Marketing Network

Sponsorships can be a powerful way for businesses to connect with their target audience, build relationships with key stakeholders, and promote their brand in a meaningful way. But in order to be truly effective, sponsorships must be aligned with a company’s brand values. For pharmaceutical companies, this means aligning sponsorships with causes that are related to health and wellness.

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TikTok cracks down on users posting about popular weight loss drugs

STAT

As the demand for GLP-1 based drugs grows, content about the new class of weight loss drugs on TikTok has fueled the flames of its popularity. Now, the social media platform has taken action against many of the users who post frequently about the medications. Dozens of accounts were suspended from TikTok in early July, many belonging to content creators who talk about their weight loss and monetize the platform via partnerships with telehealth companies that prescribe GLP-1s and other weight los

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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GPhC recruiting for chief pharmacy officer

The Pharmacist

The General Pharmaceutical Council (GPhC) is recruiting for a chief pharmacy officer to ‘bring a new pharmacy professional voice and presence’ to the regulator. The new role, which could be filled by a GPhC-registered pharmacist or pharmacy technician, will sit within the regulator’s senior leadership team and ‘will be the most senior member of the […] The post GPhC recruiting for chief pharmacy officer appeared first on The Pharmacist.

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STAT+: To get better heart data from wearables, researchers train AI to separate the signal from the noise

STAT

As wearable health devices grow more popular in the U.S., there’s a growing opportunity to track the broader adult population’s heart health. But it’s much harder for an Apple Watch to accurately detect the heart’s electrical signals and rhythm than a set of hospital-grade electrodes. Its readings are messier, often because of poor contact with the skin.

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Choosing the Right Sponsorships for Maximum Impact in the Pharmaceutical Industry 

Pharma Marketing Network

Sponsorships can be a powerful tool for pharmaceutical companies to engage with their target audience, build relationships with key stakeholders, and promote their brand in a meaningful way. But with so many different healthcare organizations and causes to choose from, it can be difficult to know where to start. Here are some tips for choosing the right sponsorships for maximum impact in the pharmaceutical industry: Start with your goals: What do you hope to achieve through your sponsorship?

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STAT+: Stanford president’s departure begs the question: Who takes the credit — or blame — in team science?

STAT

The resignation of Marc Tessier-Lavigne as president of Stanford University following an investigation into irregularities in his past research marks more than just the startling downfall of the leader of one of the nation’s top research powerhouses. The case is likely to have broader repercussions, signaling a tipping point in an ongoing and often contentious debate about how to assign blame and credit in the increasingly collaborative world of research.

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Digital Disruption in Pharma: Harnessing Technology for Effective Marketing Campaigns 

Pharma Marketing Network

The pharmaceutical industry is constantly evolving, and digital technology is playing an increasingly important role in marketing campaigns. In the past, pharmaceutical companies relied heavily on traditional marketing methods such as print ads, TV commercials, and direct mail. However, these methods are becoming less effective as consumers are increasingly turning to digital channels for information and research.

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STAT+: App developer Twill hunts for pharma partner to market its digital depression treatment

STAT

In another sign of the business headwinds facing prescription mental health apps, developer Twill will shop around for a pharmaceutical company to market Aspiro, its cognitive behavioral therapy treatment for both generalized anxiety and major depression. Twill executives told STAT the company hopes that a drugmaker developing or currently marketing a product for generalized anxiety, or GAD, and major depressive disorder, or MDD, will be interested in adding a digital therapeutic to boost the ef

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Efficacy of novel drug proven in MDD study

European Pharmaceutical Review

Phase II study results for navacaprant (NMRA-140), a novel kappa opioid receptor (KOR) antagonist for major depressive disorder (MDD) demonstrated significant and clinically meaningful improvement in depression for participants. The data “are compelling, particularly the significant improvements observed in both depressive and anhedonic symptoms,” stated Dr Roger S McIntyre, FRCPC, Professor of psychiatry and pharmacology, University of Toronto and Executive Director of the Brain and Cogni

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STAT+: House committee probes FDA inspections of pharma plants in China and India

STAT

A congressional committee is demanding the U.S. Food and Drug Administration provide detailed information about pharmaceutical plant inspections in China and India, two countries whose significant production of generic drugs and active pharmaceutical ingredients has caused concern about an overreliance on foreign manufacturers. Chinese and Indian manufacturers receive the largest number of warning letters about quality control issues from the FDA, including carcinogens in medicines, destroyed or

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Members of the Alliance for Genomic Discovery revealed

Pharma Times

Illumina and Nashville Biosciences’ have announced AbbVie, Amgen, AstraZeneca, Bayer and Merck as founding members - News - PharmaTimes

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STAT+: A new explanation for why some stubborn cancer cells resist treatment

STAT

Cancer drugs can burn through tumors like a wildfire, killing off the vast majority of malignant cells. But a few stubborn cells often end up surviving, seeding a recurrence of the disease. The prevailing theory behind this drug resistance is built on natural selection: Among the vast and genetically diverse population of cancer cells in a tumor, some have random mutations that help these cells survive an onslaught.

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Novartis acquires DTx Pharma

Express Pharma

Deal includes DTx-1252, a potential therapy for the neuromuscular disorder Charcot-Marie-Tooth disease type 1A (CMT1A), and two additional preclinical programs for other neuroscience indications Novartis has announced that it has acquired DTx Pharma, a San-Diego based, preclinical stage biotechnology company focused on leveraging its proprietary FALCON platform to develop siRNA therapies for neuroscience indications.

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Opinion: Listen: Dance helped this nurse heal from trauma. Now she’s bringing it to others

STAT

“Y ou can’t pour from an empty cup” is what registered nurse Tara Rynders learned the hard way after two decades of work and one heartbreaking, life-threatening experience of being a critical care patient herself. Before that experience, she’d always found found that dance, play, and other types of movement helped her express and heal from the trauma she encountered and held in her body every day.

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Wilson Bryan, former FDA gene therapy leader, joins consulting firm

BioPharma Dive

The agency veteran, who led the Office of Tissues and Advanced Therapies during a boom in gene and cell therapy research, retired in March.

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STAT+: States increasingly look to regulate hospital facility fees

STAT

Unexpected “facility fees” charged by hospitals have become a growing source of rage for patients, and more states are taking steps to rein them in. A new report, published by Georgetown University’s Center on Health Insurance Reforms and West Health, examined 11 states that regulate facility fees and conducted interviews with numerous government officials, patient advocates, health insurers, hospitals, and billing experts.

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EMA prepares for winter antibiotic shortages

European Pharmaceutical Review

The European Commission, the Heads of Medicines Agencies (HMA) and the European Medicines Agency have published recommendations for avoiding antibiotic shortages in the autumn/winter 2023-2024 season. These suggested actions have been developed through the Executive Steering Group on Shortages and Safety of Medicinal Products (MSSG). They complement the process to develop an EU list of critical medicines, of which a first version is anticipated to be released by the end of 2023.

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STAT+: DOJ, FTC primed for more aggressive scrutiny of health care mergers

STAT

Health care companies trying to merge can expect tougher policing from the top federal antitrust agencies, according to a set of new draft guidelines released Wednesday. The Department of Justice and Federal Trade Commission laid out 13 proposed guidelines detailing how they will judge whether proposed mergers and acquisitions are anticompetitive and should be challenged.

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Is the risk of ovarian cancer really greater in some jobs?

The Pharmacist

According to a recent study, accountants, hairdressers and beauticians are at an increased risk of developing ovarian cancer. So should they consider changing jobs? Rod Tucker delves deeper, in the latest in our Review series. The estimated lifetime risk of ovarian cancer among women born after 1960 in the UK is 2%. The causes of […] The post Is the risk of ovarian cancer really greater in some jobs?

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Twist and Cancer Research Horizons sign antibody library platform deal

Pharmaceutical Technology

Twist Bioscience and CRUK innovation arm Cancer Research Horizons have signed an agreement for licensing a library of libraries.

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Glaucoma therapy Roclanda launched by Santen

Pharma Times

By combining both netarsudil and latanoprost treatment, Roclanda reduces intraocular pressure - News - PharmaTimes

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Novartis builds on neuroscience pipeline and xRNA platform capabilities with acquisition of DTx Pharma

World Pharma News

Novartis has acquired DTx Pharma, a San-Diego based, preclinical stage biotechnology company focused on leveraging its proprietary FALCON platform to develop siRNA therapies for neuroscience indications. DTx’s lead program, DTx-1252 targets the root cause of CMT1A - the overexpression of PMP22, a protein that causes the myelin sheath that supports and insulates nerves in the peripheral nervous system to function abnormally.

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Five Career Alternatives for New PharmD Graduates

The Script

Have you recently earned your PharmD? Rx relief breaks down five career alternatives you can also consider.

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US DoD enlists VitriVax to develop one-shot vaccine for melioidosis

Pharmaceutical Technology

B. pseudomallei is resistant to many antibiotics and, without treatment, can be lethal to those infected.

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USFDA approves Sanofi-AstraZeneca’s preventive RSV therapy for babies

Express Pharma

The companies plan to make Beyfortus available in the United States ahead of the upcoming RSV season, Sanofi said, adding that it plans to share more information about the therapy’s price closer to the season The therapy, branded Beyfortus, was approved for preventing lower respiratory tract disease in infants born during or entering their first RSV season, and in children up to 24 months of age who remain vulnerable to severe RSV disease through their second such season.

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Women in Science: Inato's Liz Beatty and her aim to combat underrepresentation in clinical trials

Outsourcing Pharma

Liz Beatty is co-founder and chief strategy officer at Inato, a clinical trials platform which flips the traditional model and allows community sites to participate in the trials that are best aligned with their interests and that of their patients.

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Alzheimer’s drug donanemab ‘effective’ but ‘a way off’, says expert

The Pharmacist

There is likely to be ‘big demand’ from patients interested in Alzheimer’s drug donanemab following the results of a clinical trial published this week, but the public must be aware that access is likely to be some way off, an expert in psychiatric pharmacy has suggested. Full results from the donanemab clinical trial, released this […] The post Alzheimer’s drug donanemab ‘effective’ but ‘a way off’, says expert appeared first on The Pharmacist.

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