Wed.Nov 22, 2023

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Opinion: Physician and Rep. Raul Ruiz: The infectious disease doctor shortage threatens future pandemic preparedness

STAT

In 2009, I was practicing in the emergency department when the H1N1 pandemic emerged. Then, I saw firsthand the vital role infectious disease physicians played in not only facilitating a coordinated public health response, but also helping patients, providers, and the public navigate the uncertainty that comes with confronting a novel virus. While on the frontlines of that pandemic, I depended on our community’s infectious disease specialists as I worked in real-time to provide patients w

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ACMT Toxicology Visual Pearl: Poison Dart Frog

ALiEM - Pharm Pearls

The toxin from the golden poison dart frog most resembles which of the following in its mechanism of action? Botulinum toxin Bufotoxin Grayanotoxin Palytoxin Tetrodotoxin Photo adapted from Wilfried Berns (Wikimedia Commons) Reveal the Answer 3. Grayanotoxin – a sodium channel opener Background The golden poison dart frog ( Phyllobates terribilis ), often considered one of the most poisonous animals on the planet, secretes onto its skin the lipophilic alkaloid batrachotoxin , which irreversibly

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Trending Sources

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Overdose deaths during pregnancy spiked over the past few years, study says

STAT

Overdose deaths among pregnant or postpartum people skyrocketed between 2018 and 2021, according to new research published Wednesday in JAMA Psychiatry. The study, conducted by the National Institute on Drug Abuse (NIDA) and the National Institutes of Health, compared the incidence of maternal deaths for overdose of commonly misused psychotropic drugs (such as heroin and other opioids, including synthetic ones, or cocaine) among girls and women aged 10 to 44.

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Organon’s chief medical officer wants to change how the world sees women’s health

PharmaVoice

Dr. Juan Camilo Arjona Ferreira joined Organon in September and says the company is “like a lighthouse in women’s health” in its visibility and focus.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: U.S. Anesthesia Partners, Welsh Carson face class action over monopoly allegations

STAT

Union health plans that represent electricians and plumbers in Texas have filed a class-action lawsuit against physician group U.S. Anesthesia Partners and private equity firm Welsh, Carson, Anderson & Stowe. The lawsuit builds on the Federal Trade Commission’s complaint filed in September, which argued USAP and Welsh Carson illegally bought up anesthesia practices across Texas as a way to concentrate market power, gain negotiating leverage over health insurance companies, and raise p

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Meet the Pharmacist of the Year Award shortlist: Mohammad M Rahman

The Pharmacist

We speak to the Pharmacist/Pharmacy Team of the Year Award shortlist ahead of this year’s General Practice Awards, to be held on 8 December in London. The first entry under the spotlight from this year’s shortlist of six is Mohammad M Rahman, principal pharmacist and head of medicines management at Lewes Primary Care Network and […] The post Meet the Pharmacist of the Year Award shortlist: Mohammad M Rahman appeared first on The Pharmacist.

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More Trending

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Strides gets USFDA approval for generic Suprep Bowel Prep Kit

Express Pharma

Strides Pharma Science announced that its step‐ down wholly owned subsidiary, Strides Pharma Global Pte., Singapore, has received approval for Sodium Sulphate, Potassium Sulphate and Magnesium Sulphate Oral Solution 17.5g/ 3.13g/ 1.6g per 6 ounces (Product) from the United States Food & Drug Administration (USFDA). The product is bioequivalent and therapeutically equivalent to the Reference Listed Drug (RLD), Suprep Bowel Prep Kit Oral Solution 17.5g/ 3.13g/ 1.6g per 6 ounces of Braintree La

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What’s behind the urge to scratch that itch? Harvard researchers have a theory

STAT

That itchy feeling isn’t just in your head, in some cases it might actually be all over you. And it may literally get on your nerves. New research published Wednesday in Cell indicates that a common skin bacterium — Staphylococcus aureus — can make you feel itchy by directly acting on nerve cells. Even though itchiness is an everyday sensation, its causes remain mysterious.

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Flagship-backed microbiome biotech Evelo to shut down

BioPharma Dive

The company said it had not found “a viable alternative” to closing down in the months since it hit a clinical setback and laid off staff.

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STAT+: Evelo Biosciences, a microbiome company launched by Flagship, shuts down

STAT

Evelo Biosciences, a startup hoping to use the trillions of microbes in and on the human body to fight disease, is shutting down after running low on cash and seeing multiple drug trial failures. The biotech, which was based in Cambridge, Mass., launched in 2015 and was one of the first companies in the microbiome field, which seeks to treat disease by leveraging bacteria naturally found in and around the body.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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PREDICTOM trial backed by €21m for early Alzheimer’s detection

Pharma Times

The trial will use an AI screening platform to identify those most at risk of dementia - News - PharmaTimes

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Medtronic isn’t afraid of Wegovy’s potential to disrupt

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello, everyone. Damian here with an update on biotech’s silly season, a looming showdown in Washington, and the latest twist in the Ozempic panic. This newsletter is taking the next couple days off in the spirit of the holiday, but we’ll be back in your inbox Monday morning.

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Eli Lilly supports Alto Neuroscience in $45m Series C round

Pharmaceutical Technology

The funding will go towards the development of the company's four CNS candidates, with Phase II study data readouts expected by early 2025.

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Opinion: Listen: Living in cancer limbo

STAT

Fifteen years ago, Mara Buchbinder and colleagues came up with the concept of the “patient in waiting.” The concept described a new category of patients created by cutting-edge testing — say, prenatal diagnostics that alerted parents to potential problems, even though they might not appear. The patient in waiting was, quite literally, someone who was waiting to see if they would become ill.

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Thousands of men to participate in UK trial for prostate cancer

Pharma Times

Prostate cancer is responsible for 12,000 deaths every year in the UK - News - PharmaTimes

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Pharmalittle: European patent agency invalidates a Moderna mRNA patent; pharma ally Eshoo plans to retire

STAT

Good morning! This is Jonathan Wosen, West Coast biotech and life sciences reporter, filling in for Ed Silverman while he’s away from the Pharmalot campus. There won’t be a newsletter this Thursday or Friday because of the Thanksgiving holiday. Speaking of which, if you wake up tomorrow and realize that your turkey hasn’t thawed, never fear, you can safely cook a fully or partially frozen turkey, according to the U.S.

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Talking techbio with NVIDIA: Accelerated computing, NLP, and GenAI in drug discovery

pharmaphorum

Talking techbio with NVIDIA: Accelerated computing, NLP, and GenAI in drug discovery Mike.

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MPs told of ‘huge differences’ pharmacists make in general practice

The Pharmacist

The ‘expertise and safety’ that pharmacists working in general practice can bring to patients has been spotlighted within a parliamentary inquiry. President of the Primary Care Pharmacy Association Dr Graham Stretch was giving evidence to the Health and Social Care Committee’s new inquiry into pharmacy when he highlighted the ‘huge differences’ practice pharmacists have made. […] The post MPs told of ‘huge differences’ pharmacists make in general practice appeared first on The Pharmacist.

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Signal: Moderna mRNA patent revoked by EPO after Pfizer suit

Pharmaceutical Technology

Pfizer and BioNTech countersued Moderna following an initial August 2022 suit alleging that its patents were overly broad.

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Boris Bachmeier appointed new MD of Romaco Pharmatechnik GmbH

Express Pharma

Boris Bachmeier has just been named by Romaco Holding GmbH as the new Managing Director of the Romaco Pharmatechnik business unit in Karlsruhe (Germany). He will take over from Markus Regner, who has managed the company since 2018 and will be leaving at his own request at the end of November. All blister, heat sealing and rigid tube filling machines traded under the brand names Noack and Siebler are manufactured at the Romaco facility in Karlsruhe. “ I’m delighted to welcome Boris Bachmeier as n

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Investigating Industry Involvement in Modern Clinical Trials

Pharmaceutical Commerce

Study aims to find ways industry gets involved in the most influential clinical trials, and how transparent these trials are.

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EC approves first-line ovarian cancer treatment

European Pharmaceutical Review

The European Commission (EC) has authorised a Type II variation for the poly (ADP-ribose) polymerase (PARP) inhibitor Rubraca ® (rucaparib). The small molecule treatment is indicated as a first-line maintenance treatment for individuals with advanced ovarian cancer regardless of their BRCA mutation status, who have responded to first-line platinum-based chemotherapy.

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Navigating the shift from low-cost to highest value

Express Pharma

As we wind up another year and mark Express Pharma’s 29th anniversary, let us review the government’s expectations from the life science segment, which are both aspirational and inspirational. At the recent CII 5th Life Sciences Summit 2023, Arunish Chawla, Secretary, Department of Pharmaceuticals (DoP), Ministry of Chemicals & Fertilizers, said, “India has the potential to grow 3-4 times in value by achieving a shift from 10 per cent share of Pharma and MedTech in the manu

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Skin bacteria can save lives

World Pharma News

Infections with antibiotic-resistant bacteria are a growing global problem. Part of the solution may lie in copying the bacteria's own weapons. The research environment in Tromsø has found a new bacteriocin, in a very common skin bacterium. Bacteriocin inhibits the growth of antibiotic-resistant bacteria that are often the cause of disease and can be difficult to treat.

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Genentech and NVIDIA enter generative AI-powered drug discovery deal

Pharmaceutical Technology

Genentech has entered a research partnership with NVIDIA to expedite the discovery and development of new drugs.

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Promising drug targets to be identified by game-changting technology at MIPS Australia

Outsourcing Pharma

An exciting new instrument that will help identify promising drug targets for academia and the pharma industry has been unveiled in Australia by The Monash Institute of Pharmaceutical Sciences (MIPS).

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US Senate Committee calls pharma giants for another hearing on drug pricing

Pharmaceutical Technology

A US senate committee scheduled a hearing on prescription drug pricing with major pharmaceutical companies.

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AMR could kill 10 million in 2050, but there’s no profit in stopping it

pharmaphorum

AMR could kill 10 million in 2050, but there’s no profit in stopping it Mike.

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Promising drug targets to be identified by game-changing technology at MIPS Australia

Outsourcing Pharma

An exciting new instrument that will help identify promising drug targets for academia and the pharma industry has been unveiled in Australia by The Monash Institute of Pharmaceutical Sciences (MIPS).

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Blow to Moderna as EU nixes mRNA vaccine patent

pharmaphorum

Blow to Moderna as EU nixes mRNA vaccine patent Phil.

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Get to Know the NHC’s Newest Team Member: Shion Chang

Putting Patients First Blog

Get to Know the NHC’s Newest Team Member: Shion Chang November 22, 2023 By: Bhriana Onuoha, Senior Coordinator, Communications and Shion Chang, Director of Policy Every great organization knows that you don’t go as far as your dream — you go as far as your team. The National Health Council (NHC) prides itself on its diligent team, the behind-the-scenes power source that drives the organization towards its mission of providing a united voice for the 160 million people living with chronic diseas

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Boehringer buys cancer immunotherapy firm T3 for $507m

pharmaphorum

Boehringer buys cancer immunotherapy firm T3 for $507m Phil.

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BeiGene to acquire global license to Ensem Therapeutics’ CDK2 inhibitor

Pharmaceutical Business Review

The oral CDK2 inhibitor from Ensem is an investigational new drug (IND) application-ready asset. BeiGene R&D global head Lai Wang said: “We are committed to developing novel molecules with the potential to transform the therapeutic landscape for cancer patients, and this partnership fits well with our strategic focus on breast cancer as an area with tremendous unmet need for innovative treatment options.

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Pharmacy First: Why technology is necessary for safeguarding pharmacies

pharmaphorum

Pharmacy First: Why technology is necessary for safeguarding pharmacies Mike.

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New patent for Eli Lilly drug OLUMIANT

Drug Patent Watch

Annual Drug Patent Expirations for OLUMIANT Olumiant is a drug marketed by Eli Lilly And Co and is included in one NDA. It is available from one supplier. There are… The post New patent for Eli Lilly drug OLUMIANT appeared first on DrugPatentWatch - Make Better Decisions.

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