Mon.Jun 12, 2023

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Obesity impairs brain responses to nutrients, even after weight loss, study finds

STAT

Brain responses to nutrients in the gut are impaired in people with obesity, and that doesn’t change even after they lose weight through changes in diet, a new study finds, adding to mounting research showing the complexity and persistence of the biological effects of obesity. Using brain imaging, researchers saw that when people without obesity received nutrients, they experienced reduced activity in areas of the brain involved in food intake, suggesting the brain is signaling to them th

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Is America ready for a new kind of opioid?

PharmaVoice

Tris Pharma’s CEO is “betting the company” on a pain reliever with the power of an opioid and a lower chance of addiction.

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STAT+: The inside story of how data integrity issues roiled a biotech seen as ‘Moderna 2.0’

STAT

In February 2022, Diego Miralles, then-CEO of a buzzy new biotech called Laronde, gathered his employees in the company’s shiny new Somerville, Mass., headquarters to relay some unsettling news. An internal investigation had uncovered a “bad assay” and poor note-taking in some of the core research being conducted at the company, Miralles told Laronde’s roughly 130 staffers.

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May 2023 Newsletter

Safe Biologics

Coming Soon: ASBM/GaBI Webinar on IRA’s Medicare Price Negotiation Provisions ASBM and the Generics and Biosimilars Initiative (GaBI) are in the final planning stages for the first of two webinars examining the implications for patients and healthcare providers of the recently-passed Inflation Reduction Act (IRA). The webinars will focus on unintended consequences for patient access that may result from the implementation of IRA provisions.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Fed up with exorbitant health costs, employers and workers are taking insurers to court

STAT

Companies, unions, and workers are at a breaking point over how much they pay for health coverage. And some are so exasperated that they’re fighting their own health insurance carriers in court. A string of new lawsuits and judge orders highlights employers’ frustration with health insurers, who they believe are allowing hospitals, doctors, and other entities to charge flagrantly high prices with little to no pushback — knowing that employers and workers will ultimately pick

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First-party data: The answer to a cookie-less future

PharmaVoice

While online cookies revolutionized online advertising and are a big part of a $600 billion dollar industry, targeting consumer/patient behavior is about to get much more difficult

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More Trending

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Zai Lab looks to expand beyond China and make a global impact in oncology

PharmaVoice

Focused on making a “transformational” impact, the company is developing targeted treatments driven by specific cancer mutations.

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Ro pauses advertising of weight loss drug Wegovy amid shortages

STAT

Telehealth company Ro has paused advertising of the obesity drug Wegovy as the drug suffers shortages, a reversal in aggressive promotional efforts by the provider that involved splashy ads in subway stations. Novo Nordisk, the maker of Wegovy, said last month it would limit its starting doses for new patients and pause advertising of the drug to avoid stimulating further demand.

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May 2023 Newsletter

Safe Biologics

Coming Soon: ASBM/GaBI Webinar on IRA’s Medicare Price Negotiation Provisions ASBM and the Generics and Biosimilars Initiative (GaBI) are in the final planning stages for the first of two webinars examining the implications for patients and healthcare providers of the recently-passed Inflation Reduction Act (IRA). The webinars will focus on unintended consequences for patient access that may result from the implementation of IRA provisions.

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Decentralized clinical trials (DCTs): protect your data to reduce risk

BioPharma Dive

Decentralized clinical trials (DCTs) bring many benefits to the clinical research process, and more importantly, the patients. However, it is important to remember the risks if there is no data security process in place.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Op-ed: IRA Drug Price Controls Will Hurt Cancer Drug Development

Safe Biologics

Op-ed: IRA Drug Price Controls Will Hurt Cancer Drug Development On May 18th, an op-ed by ASBM Steering Committee Member Andrew Spiegel ran in the Reading Eagle. Mr. Spiegel is a founding member of ASBM and Executive Director of the Global Colon Cancer Association. In the op-ed, Spiegel highlights the importance of small-molecule drugs in cancer therapy, and notes how the IRA disincentivizes their development: The rate of colorectal cancer in Americans under 55 has nearly doubled since the 1

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Cardiff University begins study of schizophrenia therapy

Pharma Times

The treatment candidate, known as MDI-26478, is a positive allosteric modulator of the AMPA receptor - News - PharmaTimes

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Op-ed: IRA Drug Price Controls Will Hurt Cancer Drug Development

Safe Biologics

Op-ed: IRA Drug Price Controls Will Hurt Cancer Drug Development On May 18th, an op-ed by ASBM Steering Committee Member Andrew Spiegel ran in the Reading Eagle. Mr. Spiegel is a founding member of ASBM and Executive Director of the Global Colon Cancer Association. In the op-ed, Spiegel highlights the importance of small-molecule drugs in cancer therapy, and notes how the IRA disincentivizes their development: The rate of colorectal cancer in Americans under 55 has nearly doubled since the 1

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Illumina CEO Francis deSouza resigns weeks after surviving Icahn board battle

BioPharma Dive

DeSouza is departing unrepentant about his decision to close the Grail deal, telling colleagues his belief in the merger “remains unshakeable.

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Call for inquiry as medicine recalls and alerts increase

The Pharmacist

Pharmacy bodies have spoken out against an increasing number of medicine recalls and notifications that pharmacy teams are having to deal with. This included the Association of Independent Multiple Pharmacies (AIMp), which has called for an inquiry into the cause of the issue. The number of medicine recalls and patient safety alerts have increased in […] The post Call for inquiry as medicine recalls and alerts increase appeared first on The Pharmacist.

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Lotus Pharmaceuticals and Teraju Pharma link for marketing in Malaysia

Pharmaceutical Technology

Lotus Pharmaceuticals and Teraju Pharma have entered a strategic partnership to market Lotus’s products in a range of therapeutic areas in Malaysia. Teraju Pharma will be responsible for marketing and promoting the products using its relationships and infrastructure. The company is a specialised pharmaceutical wholesaler and holds a licence, issued by the country’s ministry of health, to import non-registered pharmaceutical products, orphan drugs and other life-saving medicines.

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Novo Nordisk invests €2.1bn in Hillerød manufacturing expansion

European Pharmaceutical Review

Novo Nordisk intends to invest 15.9 billion Danish kroner (€2.1 billion) to expand an existing active pharmaceutical ingredient (API) production facility in Hillerød, Denmark. The investment, which begins in 2023, will create additional production capacity and increase Novo Nordisk’s ability to meet future market demands. “This important investment will ensure the continuous development of our late-phase pipeline into deliveries of important medicines for treatments to patients worldwide,” state

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AstraZeneca announces agreement with Quell Therapeutics to develop, manufacture and commercialise engineered T-regulatory cell therapies for autoimmune diseases

World Pharma News

AstraZeneca has entered into an exciting collaboration, exclusive option and license agreement with Quell Therapeutics to develop multiple engineered T-regulator (Treg) cell therapies that have the potential to be curative in Type 1 Diabetes (T1D) and Inflammatory Bowel Disease (IBD) indications. Under the terms of the agreement, Quell's proprietary toolbox of Treg cell engineering modules, including its innovative Foxp3 Phenotype Lock will be leveraged to develop autologous multi-modular Treg c

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Kite’s Yescarta and Tecartus therapies show promise

Pharma Times

Objective response rate and complete response rates were encouraging for both treatments - News - PharmaTimes

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Pfizer and GSK to battle for share of new RSV vaccine market: GlobalData

Express Pharma

The European Commission (EC) recently approved GSK’s novel vaccine, Arexvy, for the prevention of lower respiratory tract infections (LRTI) caused by respiratory syncytial virus (RSV) in adults 60 years of age and older, making it the first RSV vaccine available across the EU. Arexvy was also approved by the FDA in May, becoming the first RSV vaccine authorized for use in the US.

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Novartis to acquire kidney disease biotech Chinook for up to $3.5B

BioPharma Dive

The Swiss pharma is betting that two experimental drugs the biotech has developed for IgA nephropathy will succeed in late-stage testing, one of which will deliver results later this year.

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Driving improved and equitable outcomes for IBD patients across all stages of life

pharmaphorum

Driving improved and equitable outcomes for IBD patients across all stages of life Mike.

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Novo Nordisk to invest over $2B in drug ingredient production

BioPharma Dive

The company said the spending will help it manufacture future treatments for chronic diseases, adding to a string of recent plant investments.

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Veeva R&D and Quality Summit: Delivering next-generation innovation for patients

pharmaphorum

Veeva R&D and Quality Summit: Delivering next-generation innovation for patients Mike.

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USFDA inspects JB Pharma’s manufacturing facility at Panoli, Gujarat

Express Pharma

JB Pharma’s formulations manufacturing facility – T20 located at Panoli, Gujarat was inspected by the USFDA. The inspection was conducted from June 5-9, 2023. The company informed that at the end of the inspection, the facility received “No Observations” and thus no Form 483 was issued. A statement from JB Pharma said, “The company remains committed to producing quality products, embedding a quality culture across the organisation and continuously investing in systems, processes and

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Healthware Group, Digital Therapeutics Alliance launch DTx policy report and website

pharmaphorum

Healthware Group, Digital Therapeutics Alliance launch DTx policy report and website Nicole.

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Eccogene raises funds for clinical-stage metabolic pipeline development

Pharmaceutical Technology

Clinical-stage biotechnology firm Eccogene has raised $25.23m (CNY180m) in a Series B financing round to support the development of its clinical-stage metabolic pipeline. Co-led by Zhangjiang Healthcare Venture Capital and New Alliance Capital, the financing round has seen participation from existing investors Qingsong Capital, Delos Capital and Oriza Seed Capital.

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The rise of tech bio: Powering life science innovation

pharmaphorum

The rise of tech bio: Powering life science innovation Mike.

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Novartis to acquire Chinook Therapeutics for $3.5bn

Pharmaceutical Technology

Novartis will buy US-based clinical-stage biopharmaceutical company Chinook Therapeutics in a $3.5bn deal. Chinook common stockholders will receive $3.2bn and $0.3bn in cash through contingent value rights upon achieving certain regulatory milestones. The deal is a merger of a newly formed subsidiary of the company with Chinook, which has two late-stage medicines currently under development to treat IgA nephropathy (IgAN), a rare, progressive chronic kidney disease.

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Beacon debut sheds light on Syncona’s gene therapy plans

pharmaphorum

Beacon debut sheds light on Syncona’s gene therapy plans Phil.

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Potential and Challenges of the APAC Pharmaceutical Industry

Viseven

The global pharmaceutical market is becoming more digitalized, insight-driven, and consumer-centric. Though we’re witnessing fundamental changes all over the world, each region has its peculiarities dictated by multiple local factors. In this article, we’ll focus on a pharmaceutical market in the APAC region, go through the differences between pharma in APAC and pharma in other parts of the world, and see the current state of the APAC pharma market.

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How To Safely Use Hydrocortisone Cream For Acne: Dosage And Precautions.

Welltopia Pharmacy

Discover the benefits and proper usage of hydrocortisone cream for acne treatment. Learn how it reduces inflammation, calms breakouts, and improves the appearance of acne-prone skin.

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CVS’ departure highlights challenges, opportunities for retail clinical trials

BioPharma Dive

CVS Health was one of the first retailers to launch a clinical trials business. But a number of other competitors followed, arguing they could provide easier access and more diverse studies.

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Thank you for the payment

PharmaState Academy

Thank you for the payment. Please check your email id (Inbox/spam/other folders) for the payment reciept. You will be added to a WhatsApp group within 1 day. Happy Learning! - PharmaState Academy #FromYouToYou+ The post Thank you for the payment appeared first on PharmaState Academy.

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Who’s saying what? Internet of Things mentions in company filings of pharmaceutical industry increased by 120% in Q1 2023

Pharmaceutical Technology

The global pharmaceutical industry experienced a 120% rise in company filings mentions of internet of things in Q1 2023 compared with the previous quarter, with the highest share accounted for by Moderna, according to GlobalData’s analysis of over 61 pharmaceutical company filings. The growing application of Internet of Things will prove to have a transformative impact across the Healthcare sector.