STAT

JANUARY 9, 2023

Wall Street had been watching sales figures closely, for fear that competition from biosimilars — a form of generic — and new medicines from rival drugmakers could cut into the sales that have fueled Regeneron’s growth since Eylea was approved in 2011. Continue to STAT+ to read the full story…

Biosimilars 219

Biosimilars 219

STAT

NOVEMBER 18, 2022

Amid ongoing concerns over the use of medically important antibiotics given to food-producing livestock and farmed fish, sales of veterinary medicines across Europe dropped by nearly half between 2011 and 2021, which regulators reported is the biggest drop ever recorded and a sign that campaigns to reduce use are working.

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STAT

OCTOBER 19, 2022

In 2011, the same year that Makena received accelerated approval from the FDA, I was a member of a similar FDA advisory committee hearing in which we considered withdrawing the breast cancer indication for the drug Avastin. We’ve been here before.

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STAT

FEBRUARY 21, 2024

Founded in 2011, Dario started with a diabetes app targeted at consumers before expanding it to hypertension and weight management. The move is a bet that a consolidated offering can attract a critical mass of large customers in a market where profits have been elusive.

Diabetes 232

Diabetes 232

STAT

AUGUST 3, 2023

In 2011, President Obama signed the National Alzheimer’s Project Act into law, establishing a national goal of preventing and effectively treating the disease by 2025. Medicare’s policies are creating obstacles that make it more difficult for patients who are highly likely to benefit to obtain access to diagnosis and treatment.

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ALiEM - Pharm Pearls

JANUARY 22, 2024

2011 Oct 18;183(15):E1152. Epub 2011 Sep 12. Curr Infect Dis Rep. 2009 Jan;11(1):66-72. doi: 10.1007/s11908-009-0010-x. PMID: 19094827. Shiao CC, Lin SY. Eschar: a clue to scrub typhus. doi: 10.1503/cmaj.101929. PMID: 21911554; PMCID: PMC3193135.

Documentation 156

Documentation Hospitals 156

STAT

APRIL 18, 2023

A February 2023 report from Chartis , a health care consulting firm, found that 217 labor and delivery units have closed across the nation since 2011. The trend of rural hospitals shuttering perinatal services is not new. When these facilities close, the care of both pregnant people and their newborns must occur elsewhere.

Hospitals 243

Hospitals 243

RX Note

JUNE 11, 2023

Mobile Application Mobile application for Medscape was released in 2009 and 2011 for iOS and Android system respectively. External Links Medscape - The First 5 Years, 2005 The most popular iPhone medical app, Medscape, is now on Android, 2011 Do not forget to download the database for offline usage.

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Express Pharma

NOVEMBER 30, 2023

In the dynamic landscape of pharmaceutical contract manufacturing, the year 2022 witnessed unprecedented growth in revenues, marking the highest surge since 2011. This growth rate is the highest recorded since 2011 for commercial contract dose manufacturing revenues, and surprisingly exceeds the strong growth experienced in 2021.

Vaccines 92

Vaccines Drug Pricing 92

RX Note

JANUARY 25, 2024

External Links MyHEALTH - Food-Drug Interaction Dangerous Food-Drug Interactions, 2008 Food-Drug Interactions, 2011 On the other hand, we shall educate patients on potential drug-food interactions to minimize the risk.

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Pharmafile

AUGUST 24, 2022

The West African nation has successfully eliminated dracunculiasis (Guinea worm disease), elephantiasis (lymphatic filariasis), human African trypanosomiasis (sleeping sickness) and trachoma, in an effort spanning between 2011 and 2022. read more.

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The Guardian - Pharmaceutical Industry

MARCH 3, 2023

It was patented in 1993, eventually approved in 2011 and is now one of the leading treatments of advanced prostate cancer, branded as Zytiga. In the early 1990s, he and his colleagues at the Institute of Cancer Research in London designed the hormone therapy drug abiraterone acetate.

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Express Pharma

MARCH 21, 2024

Since Roche ‘s Zelboraf gained (vemurafenib) FDA approval in 2011, significant strides have been made in BRAF-targeted cancer therapies, underscoring the significance of combating BRAF mutations in melanoma.

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Pharma in Brief

FEBRUARY 8, 2023

Dr. Levine was originally appointed as a Member and Vice-chairperson of the Board in 2011 and served two full terms, becoming Chairperson in February 2018. Under the Patent Act , the Chairperson and other Board Members can serve a maximum of two five-year terms. Mr. Digby replaces the Board’s previous Chairperson, Dr. Mitchell Levine.

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European Pharmaceutical Review

MARCH 1, 2024

MHRA confirmed that this new marketing authorisation was granted to Amgen Limited, as a line extension of the original marketing authorisation for XGEVA 120mg solution for injection, which was granted on 13 July 2011. The post New antibody drug formulation wins novel MHRA approval appeared first on European Pharmaceutical Review.

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Express Pharma

FEBRUARY 1, 2024

The R21/Matrix-M vaccine was designed in 2011 as a potential improvement on the RTS, S/AS01 malaria vaccine designed in the 1980s. A phase II trial in Burkina Faso, reporting in 2021, was the first to show that R21/Matrix-M could reach the WHO-specified target of 75 per cent efficacy in African children.

Vaccines 99

Vaccines Immunity Immunization 99

Pharmaceutical Business Review

SEPTEMBER 11, 2023

The US regulator granted orphan drug designation to Lymphir to treat peripheral T-cell lymphoma (PTCL) and CTCL in 2011 and 2013, respectively. “We do not expect these efforts will impact our cash runway.” The treatment obtained regulatory approval in Japan for these two indications in 2021.

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Pharmaceutical Technology

JUNE 19, 2023

Novartis and Incyte Corp’s Jakafi was the first FDA-approved drug for the treatment of myelofibrosis in November 2011. First-in-line treatment for myelofibrosis currently involves treatment with Jakafi (ruxolitinib) in combination with other drugs such as danazol.

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European Pharmaceutical Review

DECEMBER 14, 2023

Between 1999 and 2001, it supported 17 percent of withdrawals, between 2002 and 2011, it supported 26 percent of withdrawals and by 2012 to 2016, 80 percent of withdrawals were supported by observational studies (cohort, case-control, or other epidemiologic design). Meta-analyses contributed least frequently (31.4 EMA/95098/2010.

Medical Records 113

Medical Records Vaccines Hospitals Drug Development 113

Pharmaceutical Business Review

AUGUST 7, 2023

The subsidiary, Daiichi Sankyo RD Novare (RD Novare), with nearly 400 employees was initially named as Daiichi Sankyo RD Associe in 2006 and was changed to the current one in 2011. In the end of March next year, it is claimed to complete its business as a corporate entity.

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RX Note

DECEMBER 11, 2023

External Links Systemic Drugs with Ocular Side Effects, 2011 The ocular adverse effects of oral drugs, 2021 Common Drugs Known to Cause Vision Changes or Damage Eye inflammation Bisphophonates (e.g. tamsulosin) Colour discrimination Digoxin (with toxicity) - yellow/green vision PDE-5 inhibitors (e.g.

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Express Pharma

APRIL 6, 2023

The drug was granted accelerated approval in 2011 but ensuing studies did not verify the clinical benefit of the drug. Makena and its generic versions are the only approved treatments for reducing the risk of preterm birth, which affects one in every 10 babies in the US.

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pharmaphorum

JANUARY 25, 2023

BMS’ lawsuit claims that Imjudo (tremelimumab) infringes two patents covering its own CTLA4 drug Yervoy (ipilimumab), which has been on the market since 2011 and is a key component of combination therapies for cancer with BMS’ PD-1 inhibitor Opdivo (nivolumab).

Chemotherapy 52

Chemotherapy 52

RX Note

MARCH 28, 2023

Feeding Analgesia Sedation Thromboembolic prophylaxis Head-up Ulcer prophylaxis Glycaemic control Spontaneous breathing trial Bowel movement Indwelling catheter Drug de-escalation External Links Give your patient a fast hug (at least) once a day, 2005 Critically ill patients need "FAST HUGS BID" (an updated mnemonic), 2009 A Standardized, Structured (..)

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The Guardian - Pharmaceutical Industry

JULY 6, 2022

UK pharmaceutical firm to spin off Haleon – which will include brands such as Sensodyne and Panadol – in largest listing since 2011 Investors in the British pharmaceuticals giant GSK have voted to approve a demerger of its consumer brands into a new company, Haleon , firing the starting gun on the largest London stock market listing in a decade.

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ALiEM - Pharm Pearls

NOVEMBER 27, 2023

Gynecol Surg 8, 129–134 (2011). Ultrasonographic findings in Fitz-Hugh-Curtis syndrome: a thickened or three-layer hepatic capsule. Yeungnam Univ J Med 35(1), 127-129 (2018). Theofanakis, C.P., Kyriakidis, A.V. Fitz-Hugh–Curtis syndrome. link] van Dongen PW. Diagnosis of Fitz-Hugh-Curtis syndrome by ultrasound. 1993 Jul;50(2):159-62.

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PharmaShots

APRIL 26, 2023

The therapy also showed a reduction in need or eligibility for SRT Ref: Businesswire | Image: Bristol Myers Squibb Related News:- BMS’ Camzyos (mavacamten) Receives the US FDA’s Approval for the Treatment of Symptomatic New York Heart Association Class II-III Obstructive HCM

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Pharmaceutical Technology

APRIL 7, 2023

Makena was approved by the FDA under the accelerated approval pathway in 2011 to reduce the risk of preterm birth in women with a singleton pregnancy who have a history of spontaneous preterm birth. The decision was made after studies did not prove the effectiveness of the drug in preventing preterm birth.

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Pharmaceutical Technology

APRIL 7, 2023

Makena was approved by the FDA under the accelerated approval pathway in 2011 to reduce the risk of preterm birth in women with a singleton pregnancy who have a history of spontaneous preterm birth. The decision was made after studies did not prove the effectiveness of the drug in preventing preterm birth.

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pharmaphorum

FEBRUARY 23, 2021

Any changes to AMNOG will likely be a worry to industry as there has already been a toughening in AMNOG assessments since 2011.”. The AMNOG (Act on the Reform of the Market for Medicinal Products) was implemented on the 1 January 2011. Figure 1: AMNOG procedures and findings, 2011-2019. Tougher pricing?

Biosimilars 70

Biosimilars Medical Records 70

European Pharmaceutical Review

AUGUST 23, 2022

To achieve this objective, the regulation amends Directive 2011/24/EU on the application of patients’ rights in cross?border Directive 2011/24/EU had the merit of drawing attention to the need for an appropriate and centralised assessment of health technologies but failed to ensure effective harmonisation on the issue. Lorgelly PK.,

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ALiEM - Pharm Pearls

JUNE 5, 2023

2011 Dec;1(6):496-501. Anthrax: A disease of biowarfare and public health importance. World J Clin Cases. 2015;3(1):20-33. doi: 10.12998/wjcc.v3.i1.20 Kamal SM, Rashid AK, Bakar MA, Ahad MA. Anthrax: an update. Asian Pac J Trop Biomed. doi: 10.1016/S2221-1691(11)60109-3. PMID: 23569822 ; PMCID: PMC3614207. Simonsen KA, Chatterjee K.

Vaccines 254

Vaccines 254

Pharmaceutical Technology

NOVEMBER 3, 2022

A Quantitative View on Award Criteria in Tenders in the EU5 from 2011 to 2020 , Genane C, Trenti S In-Person and Virtual Poster Session 3 Date: Tuesday 8 November 2022 Poster Session Time: 10:00–13:15 HPR150: P&R Policies and Macro-Trends Pertinent to CGTs: Where Are the Main Barriers and Who Leads the Efforts to a Greater Access?

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Pharmaceutical Technology

APRIL 20, 2023

Initially reported in 2011, CircRNA is a naturally occurring class of RNA. Targovax has unveiled plans to rebrand as Circio , reflecting its strategic shift to focus on expediting the development of its innovative circular RNA (circRNA) platform.

Vaccines 96

Vaccines 96

RX Note

APRIL 1, 2024

Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents, 2023 External Links DynaMed - Attention Deficit Hyperactivity Disorder (ADHD) in Children and Adolescents Patterns of comorbidity, functioning, and service use for US children with ADHD, 2011 Mortality, ADHD, and psychosocial adversity (..)

Labelling 40

Labelling 40

pharmaphorum

MAY 23, 2022

The results generated in the study will be combined with data from Tohoku’s Medical Megabank Project (TMM), a wide-ranging national project that is tracking the health of the Japanese population, originally set up in response to the 2011 earthquake and tsunami.

Pharmaceutical Manufacturing 90

Pharmaceutical Manufacturing 90

pharmaphorum

OCTOBER 7, 2020

She published her findings in 2011, and later that year started collaborating with Doudna, a biochemistry specialist. In 2011, Emmanuelle Charpentier and Jennifer Doudna had no idea that their first meeting, in a café in Puerto Rico, would be life-changing. — The Nobel Prize (@NobelPrize) October 7, 2020.

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