ALiEM - Pharm Pearls
MARCH 5, 2024
The active compound, salicin, is metabolized to salicylic acid in the body providing analgesic and antipyretic effects [2]. European Journal of Clinical Pharmacology. European Journal of Clinical Pharmacology. Willow tree bark contains salicin from which aspirin (acetylsalicylic acid) can be derived.
European Pharmaceutical Review
JUNE 28, 2022
Some examples of HPAPIs are cytotoxic compounds and hormones such as oestrogen. A new compound of unknown potency and toxicity. Over 25 percent of total drugs worldwide are classified as containing HP compounds and 30 percent of product candidates in the development pipeline are also HPAPIs, showing that this trend will continue.
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ALiEM - Pharm Pearls
NOVEMBER 1, 2023
 Deferoxamine binds with ferric iron (Fe3+) to form ferrioxamine, a water-soluble compound excreted in the urine. As Hypersensitivity reactions to rifampin: Pathogenetic mechanisms, clinical manifestations, management strategies, and review of the anaphylactic-like reactions. Medicine (Baltimore) 1999;78(6):361-9.
European Pharmaceutical Review
JULY 13, 2023
While this is essential in the interrogation of novel compounds for which we know very little about their efficacy and safety, it is also true that some biomedical research is highly wasteful. Cannabis complications There are notable complexities to researching medical cannabis using a linear approach to clinical translation.
RX Note
JUNE 11, 2023
IWK Compounding Formulas USP-NF WHO Pharmacopoeia Pregnancy Australia TGA Best Use of Medicines in Pregnancy Pregnancy and Breastfeeding Medicines Guide
RX Note
JANUARY 21, 2023
Adverse Drug Reaction Drug Induced Diseases, 2018 Meyler's Side Effects of Drugs, 2015 Antibiotics The Sanford Guide to Antimicrobial Therapy, 2022 Breastfeeding Briggs' Drugs in Pregnancy and Lactation, 2021 Hale's Medications and Mothers' Milk, 2021 Clinical Practice Applied Therapeutics, 2018 Conn’s Current Therapy, 2022 Current Medical Diagnosis (..)
Eye on FDA
JANUARY 5, 2022
Here is where FDA currently has vacancies: Bone, Reproductive and Urologic Drugs Advisory Committee – 4 vacancies Gastrointestinal Drugs Advisory Committee – 1 vacancy Pharmaceutical Science and Clinical Pharmacology Advisory Committee – 4 vacancies Pharmaceutical Compounding Advisory Committee – 1 vacancy.
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